Patents by Inventor Lorenz Lehmann

Lorenz Lehmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • System and method for linking data records from different databases
    Patent number: 11386126
    Abstract: Systems and methods for linking HCPs from an MDM system and publication authors from a second source data system. Distances between the HCPs and the publication authors may be determined, and an HCP and a publication author may be connected if their distance is below a threshold. The connected data points may be used to train a machine learning model to determine a probability that an HCP matches a publication author. An upper bound and a lower bound may be set. Data points with the probability over the upper bound may be sent out as matches, data points below the lower bound may be disregarded as not a match, and data points between the upper bound and lower bound may be labeled for manual verification.
    Type: Grant
    Filed: January 31, 2020
    Date of Patent: July 12, 2022
    Assignee: Veeva Systems Inc.
    Inventors: Lorenz Lehmann, Igor Praznik, Alexander Darius Emami-Nemini
  • ABHD5 AND PARTIAL HDAC4 FRAGMENTS AND VARIANTS AS A THERAPEUTIC APPROACH FOR THE TREATMENT OF CARDIOVASCULAR DISEASES
    Publication number: 20220195398
    Abstract: The present invention relates to Abhydrolase containing domain 5 (ABHD5) and N-terminal fragments of HDAC4 (HDAC4-NT) and variants of the aforementioned peptides for the treatment and prevention of heart failure. The present invention further provides vectors for the cardiomyocyte-specific expression of said peptides and a test system comprising ABHD5 for the identification of novel compounds which are useful for the treatment of heart failure.
    Type: Application
    Filed: March 11, 2022
    Publication date: June 23, 2022
    Inventors: Johannes Backs, Zegeye Jebessa, Lorenz Lehmann, Hugo Katus, Oliver Müller
  • ABHD5 and partial HDAC4 fragments and variants as a therapeutic approach for the treatment of cardiovascular diseases
    Patent number: 11312943
    Abstract: The present invention relates to Abhydrolase containing domain 5 (ABHD5) and N-terminal fragments of HDAC4 (HDAC4-NT) and variants of the aforementioned peptides for the treatment and prevention of heart failure. The present invention further provides vectors for the cardiomyocyte-specific expression of said peptides and a test system comprising ABHD5 for the identification of novel compounds which are useful for the treatment of heart failure.
    Type: Grant
    Filed: January 29, 2018
    Date of Patent: April 26, 2022
    Assignee: RUPRECHT-KARLS-UNIVERSITÄT HEIDELBERG
    Inventors: Johannes Backs, Zegeye Jebessa, Lorenz Lehmann, Hugo Katus, Oliver Müller
  • ABHD5 AND PARTIAL HDAC4 FRAGMENTS AND VARIANTS AS A THERAPEUTIC APPROACH FOR THE TREATMENT OF CARDIOVASCULAR DISEASES
    Publication number: 20180258407
    Abstract: The present invention relates to Abhydrolase containing domain 5 (ABHDS) and N-terminal fragments of HDAC4 (HDAC4-NT) and variants of the aforementioned peptides for the treatment and prevention of heart failure. The present invention further provides vectors for the cardiomyocyte-specific expression of said peptides and a test system comprising ABHDS for the identification of novel compounds which are useful for the treatment of heart failure.
    Type: Application
    Filed: January 29, 2018
    Publication date: September 13, 2018
    Inventors: Johannes Backs, Zegeye Jebessa, Lorenz Lehmann, Hugo Katus, Oliver Müller
  • ABHD5 and partial HDAC4 fragments and variants as a therapeutic approach for the treatment of cardiovascular diseases
    Patent number: 9914912
    Abstract: The present invention relates to Abhydrolase containing domain 5 (ABHD5) and N-terminal fragments of HDAC4 (HDAC4-NT) and variants of the aforementioned peptides for the treatment and prevention of heart failure. The present invention further provides vectors for the cardiomyocyte-specific expression of said peptides and a test system comprising ABHD5 for the identification of novel compounds which are useful for the treatment of heart failure.
    Type: Grant
    Filed: February 17, 2014
    Date of Patent: March 13, 2018
    Assignee: Ruprecht-Karls-University Heidelberg
    Inventors: Johannes Backs, Zegeye Jebessa, Lorenz Lehmann, Hugo Katus, Oliver Müller
  • ABHD5 AND PARTIAL HDAC4 FRAGMENTS AND VARIANTS AS A THERAPEUTIC APPROACH FOR THE TREATMENT OF CARDIOVASCULAR DISEASES
    Publication number: 20160108376
    Abstract: The present invention relates to Abhydrolase containing domain 5 (ABHD5) and N-terminal fragments of HDAC4 (HDAC4-NT) and variants of the aforementioned peptides for the treatment and prevention of heart failure. The present invention further provides vectors for the cardiomyocyte-specific expression of said peptides and a test system comprising ABHD5 for the identification of novel compounds which are useful for the treatment of heart failure.
    Type: Application
    Filed: February 17, 2014
    Publication date: April 21, 2016
    Applicant: Ruprecht-Karls-Universitat Heidelberg
    Inventors: Johannes Backs, Zegeye Jebessa, Lorenz Lehmann, Hugo Katus, Oliver Müller