Patents by Inventor Lorenzo Magarotto

Lorenzo Magarotto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process of thermodynamical activation of water-insoluble drugs loaded into cross-linked polymers
    Patent number: 8889182
    Abstract: The present invention refers to a process to prepare a highly activated composite of one or more water-insoluble drugs, said process comprising the steps of: (a) subjecting said water-insoluble drug and a cross-linked polymer to co-grinding; (b) exposing the ground product of step a. to contact with water or water vapors. The resulting composite contains large amounts of drug in the easily soluble amorphous form, reduced amounts of drug in the nanocrystalline form, and is substantially free from practically insoluble drug crystals.
    Type: Grant
    Filed: June 3, 2002
    Date of Patent: November 18, 2014
    Assignee: Aptalis Pharma Limited
    Inventors: Massimo Bresciani, Lorenzo Magarotto, Luca Dobetti
  • Process of thermodynamical activation of water-insoluble drugs loaded into cross-linked polymers
    Publication number: 20040213840
    Abstract: The present invention refers to a process to prepare a highly activated composite of one or more water-insoluble drugs, said process comprising the steps of: (a) subjecting said water-insoluble drug and a cross-linked polymer to co-grinding; (b) exposing the ground product of step a. to contact with water or water vapours. The resulting composite contains large amounts of drug in the easily soluble amorphous form, reduced amounts of drug in the nanocrystalline form, and is substantially free from practically insoluble drug crystals.
    Type: Application
    Filed: December 24, 2003
    Publication date: October 28, 2004
    Inventors: Massimo Bresciani, Lorenzo Magarotto, Luca Dobetti