Patents by Inventor Lorenzo Pradella

Lorenzo Pradella has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Macrolides with anti-inflammatory activity
    Patent number: 6455576
    Abstract: 3′-Des-dimethylamino-9-oxyimino macrolides of formula (I) endowed with anti-inflammatory activity and their pharmaceutical use are described.
    Type: Grant
    Filed: September 5, 2001
    Date of Patent: September 24, 2002
    Assignee: Zambon Group S.p.A.
    Inventors: Franco Pellacini, Daniela Botta, Stefano Romagnano, Ermanno Moriggi, Lorenzo Pradella
  • Benzazine derivatives as phosphodiesterase 4 inhibitors
    Patent number: 6358973
    Abstract: Compounds of formula I: wherein A is a heterocycle containing a nitrogen atom and optionally saturated or unsaturated and optionally further substituted by an oxo group (═O); R is: hydrogen, cyano, (C1-4)alkoxycarbonyl, carbamoyl; optionally substituted (C4-7)-cycloalkyl, aryl or heterocycle; (C1-8)alkyl, (C2-8)alkenyl or (C2-8)alkynyl optionally branched and/or substituted by (C4-7) cycloalkyl, aryl or heterocycle; aryloxy, heterocyclyloxy, aryl(C1-4)alkoxy, heterocyclyl(C1-4)alkoxy, amino substituted by one or two (C1-4)alkyl group(s), aryl-amino, heterocyclyl-amino, aryl(C1-4)alkyl-amino, or heterocyclyl(C1-4)alkylamino; Y is methylene or ethylene; W is an optionally substituted aryl or heterocycle; R1 is hydrogen, (C4-7)cycloalkyl or a (C2-8)alkyl, (C2-8)alkenyl or (C2-8)alkynyl group optionally substituted by hydroxy, oxo, (C4-7)cycloalkyl, aryl or heterocycle, and optionally interrupted by one or more heteroatom(s) or heterogroup(s); R2 is a (C1-6)alkyl or polyfluoro(C1-6)alkyl gr
    Type: Grant
    Filed: April 13, 2001
    Date of Patent: March 19, 2002
    Assignee: Zambon Group S.p.A.
    Inventors: Mauro Napoletano, Gabriele Norcini, Giancarlo Grancini, Franco Pellacini, Gabriele Morazzoni, Lorenzo Pradella
  • Hydroxymethyl derivatives of 2-amino-1,2,3,4-tetrahydronaphthalene as cardiovascular agent
    Patent number: 6232348
    Abstract: Compounds of formula (I) wherein R, R′, R″, R1, R2, R3, R4, R5, R6, X, Y, m, n, and p have the meanings reported in the description; and their pharmaceutically acceptable salts are described.
    Type: Grant
    Filed: August 12, 1999
    Date of Patent: May 15, 2001
    Assignee: Zambon Group S.p.A.
    Inventors: Stefania Montanari, Paolo Cavalleri, Francesco Santangelo, Cristina Fraire, Giancarlo Grancini, Napoletano Mauro, Francesco Marchini, Lorenzo Pradella, Claudio Semeraro