Patents by Inventor Loreta Gudynaite-Savitch
Loreta Gudynaite-Savitch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10407705Abstract: The present invention provides an isolated fungal cell that is capable of producing one or more biomass-degrading enzymes and that exhibits increased or decreased expression or copy number of a polynucleotide encoding a PtaB-like protein. Also provided is a fermentation processes for producing one or more biomass-degrading enzymes comprising a fungal cells exhibiting increased or decreased expression or copy number of a polynucleotide encoding a PtaB-like protein. The biomass-degrading enzymes produced by the isolate fungal cell and fermentation processes of the present invention may be used in a process to produce soluble sugars from biomass.Type: GrantFiled: October 19, 2017Date of Patent: September 10, 2019Assignee: IOGEN ENERGY CORPORATIONInventors: Philippe J. Dufresne, Adam H. Colville, Barbara Fryzuk, Loreta Gudynaite-Savitch, Christopher M. D. Hindle, Boguslaw Ploch, John J. Tomashek
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Publication number: 20180030492Abstract: The present invention provides an isolated fungal cell that is capable of producing one or more biomass-degrading enzymes and that exhibits increased or decreased expression or copy number of a polynucleotide encoding a PtaB-like protein. Also provided is a fermentation processes for producing one or more biomass-degrading enzymes comprising a fungal cells exhibiting increased or decreased expression or copy number of a polynucleotide encoding a PtaB-like protein. The biomass-degrading enzymes produced by the isolate fungal cell and fermentation processes of the present invention may be used in a process to produce soluble sugars from biomass.Type: ApplicationFiled: October 19, 2017Publication date: February 1, 2018Inventors: Philippe J. Dufresne, Adam H. Colville, Barbara Fryzuk, Loreta Gudynaite-Savitch, Christopher M.D. Hindle, Boguslaw Ploch, John J. Tomashek
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Patent number: 9834804Abstract: The present invention provides an isolated fungal cell that is capable of producing one or more biomass-degrading enzymes and that exhibits increased or decreased expression or copy number of a polynucleotide encoding a PtaB-like protein. Also provided is a fermentation processes for producing one or more biomass-degrading enzymes comprising a fungal cells exhibiting increased or decreased expression or copy number of a polynucleotide encoding a PtaB-like protein. The biomass-degrading enzymes produced by the isolate fungal cell and fermentation processes of the present invention may be used in a process to produce soluble sugars from biomass.Type: GrantFiled: December 12, 2012Date of Patent: December 5, 2017Assignee: Iogen Energy CorporationInventors: Philippe J. Dufresne, Adam H. Colville, Barbara Fryzuk, Loreta Gudynaite-Savitch, Christopher M. D. Hindle, Boguslaw Ploch, John J. Tomashek
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Patent number: 9279163Abstract: Provided are isolated cellobiohydrolases comprising a modified Glycoside Hydrolase (GH) Family 7 catalytic domain, a GH Family 7 catalytic domain and a modified Family 1 carbohydrate binding module (CBM), or both a modified Family 7 catalytic domain and a modified Family 1 CBM. Such isolated cellobiohydrolases exhibit from 45% to about 99.9% amino acid sequence identity to amino acids 1-436 of SEQ ID NO: 1 or to amino acids 1-438 of SEQ ID NO: 2 and improved activity on process substrates. Also provided are genetic constructs and genetically modified microbes for expressing the isolated cellobiohydrolases, a process for producing the isolated cellobiohydrolases, cellulase enzyme mixtures comprising the isolated cellobiohydrolase and a process for hydrolyzing a cellulosic substrate with such cellulase enzyme mixtures.Type: GrantFiled: August 24, 2012Date of Patent: March 8, 2016Assignee: IOGEN ENERGY CORPORATIONInventors: Jacqueline Montalibet, Loreta Gudynaite-Savitch, Christopher Hill, Christopher D. Hindle, James A. Lavigne, Nabil Masri, Fuad Tahna, John J. Tomashek
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Patent number: 9238806Abstract: The present invention relates to a depilling composition comprising an enzyme mixture that comprises a Family 45 cellulase and one or more additional cellulases selected from a Family 5 cellulase, a Family 6 cellulase or a combination thereof. The enzyme mixture may be characterized in that the Family 45 and Family 5 cellulases or the Family 45 and Family 6 cellulases are present at a weight ratio that exhibits synergy in an assay that measures specific depilling activity. The enzyme mixture may be secreted by a genetically modified microbe overexpressing the foregoing cellulases. Also provided is a process for depilling that comprises a step of contacting cellulose-containing goods with the depilling composition.Type: GrantFiled: February 9, 2012Date of Patent: January 19, 2016Assignee: Novozymes A/SInventors: Christopher Hill, John J. Tomashek, Loreta Gudynaite-Savitch, Guylaine Therrien, Sophie Calixte
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Patent number: 8936929Abstract: The present invention relates to novel xylose-fermenting yeast strains (for example, yeast of the genus Saccharomyces, e.g., S. cerevisiae) with an enhanced ability to ferment the xylose (and/or another pentose sugar) present in a lignocellulosic hydrolysate to a fermentation product(s) (for example, an alcohol (e.g., ethanol) or a sugar alcohol (e.g., xylitol)).Type: GrantFiled: October 3, 2013Date of Patent: January 20, 2015Assignee: Iogen Energy CorporationInventors: Jennifer Donaldson, Jan-Maarten A. Geertman, Glenn D. Munkvold, Gary Pigeau, Philippe J. Dufresne, Loreta Gudynaite-Savitch
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Publication number: 20140295504Abstract: The present invention provides an isolated fungal cell that is capable of producing one or more biomass-degrading enzymes and that exhibits increased or decreased expression or copy number of a polynucleotide encoding a PtaB-like protein. Also provided is a fermentation processes for producing one or more biomass-degrading enzymes comprising a fungal cells exhibiting increased or decreased expression or copy number of a polynucleotide encoding a PtaB-like protein. The biomass-degrading enzymes produced by the isolate fungal cell and fermentation processes of the present invention may be used in a process to produce soluble sugars from biomass.Type: ApplicationFiled: December 12, 2012Publication date: October 2, 2014Inventors: Philippe J. Dufresne, Adam H. Colville, Barbara Fryzuk, Loreta Gudynaite-Savitch, Christopher M.D. Hindle, Boguslaw Ploch, John J. Tomashek
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Publication number: 20140030795Abstract: The present invention relates to novel xylose-fermenting yeast strains (for example, yeast of the genus Saccharomyces, e.g., S. cerevisiae) with an enhanced ability to ferment the xylose (and/or another pentose sugar) present in a lignocellulosic hydrolysate to a fermentation product(s) (for example, an alcohol (e.g., ethanol) or a sugar alcohol (e.g., xylitol)).Type: ApplicationFiled: October 3, 2013Publication date: January 30, 2014Applicant: IOGEN ENERGY CORPORATIONInventors: Jennifer Donaldson, Jan-Maarten A. Geertman, Glenn D. Munkvold, Gary Pigeau, Philippe J. Dufresne, Loreta Gudynaite-Savitch
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Publication number: 20130337542Abstract: The present invention relates to a depilling composition comprising an enzyme mixture that comprises a Family 45 cellulase enzyme component and one or more additional cellulase enzyme components selected from a Family 5 cellulase, a Family 6 cellulase or a combination thereof. The enzyme mixture may be characterized in that the Family 45 and the Family 5 cellulase enzyme components or the Family 45 and the Family 6 cellulase enzyme components are present at a weight ratio that exhibits synergy in an assay that measures specific depilling activity. The enzyme mixture may be secreted by a genetically modified microbe overexpressing theforegoing cellulase enzyme components. Also provided is a process for depilling that comprises a step of contacting cellulose-containing goods with the depilling composition.Type: ApplicationFiled: February 9, 2012Publication date: December 19, 2013Applicant: Novozymes A/SInventors: Christopher Hill, John J. Tomashek, Loreta Gudynaite-Savitch, Guylaine Therrien, Sophie Calixte
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Patent number: 8603788Abstract: The present invention relates to novel xylose-fermenting yeast strains (for example, yeast of the genus Saccharomyces, e.g., S. cerevisiae) with an enhanced ability to ferment the xylose (and/or another pentose sugar) present in a lignocellulosic hydrolysate to a fermentation product(s) (for example, an alcohol (e.g., ethanol) or a sugar alcohol (e.g., xylitol)).Type: GrantFiled: December 30, 2010Date of Patent: December 10, 2013Assignee: Iogen Energy CorporationInventors: Jennifer Donaldson, Jan-Maarten A. Geertman, Glenn D. Munkvold, Gary Pigeau, Philippe J. Dufresne, Loreta Gudynaite-Savitch
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Publication number: 20130052694Abstract: Provided are isolated cellobiohydrolases comprising a modified Glycoside Hydrolase (GH) Family 7 catalytic domain, a GH Family 7 catalytic domain and a modified Family 1 carbohydrate binding module (CBM), or both a modified Family 7 catalytic domain and a modified Family 1 CBM. Such isolated cellobiohydrolases exhibit from 45% to about 99.9% amino acid sequence identity to amino acids 1-436 of SEQ ID NO: 1 or to amino acids 1-438 of SEQ ID NO: 2 and improved activity on process substrates. Also provided are genetic constructs and genetically modified microbes for expressing the isolated cellobiohydrolases, a process for producing the isolated cellobiohydrolases, cellulase enzyme mixtures comprising the isolated cellobiohydrolase and a process for hydrolysing a cellulosic substrate with such cellulase enzyme mixtures.Type: ApplicationFiled: August 24, 2012Publication date: February 28, 2013Applicant: Iogen Energy CorporationInventors: Jacqueline Montalibet, Loreta Gudynaite-Savitch, Christopher Hill, Christopher D. Hindle, James A. Lavigne, Nabil Masri, Fuad Tahna, John J. Tomashek
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Patent number: 8323931Abstract: A fermentation process for the production of cellulase mixtures is provided. The process comprises providing a genetically modified host filamentous fungus that overexpresses a Xyr1 transcription factor and/or that is partially or completely deficient in expressing one or more hemicellulase enzyme. The host filamentous fungus is cultured in a medium comprising a carbon source. The carbon source contains from about 60 wt % to about 100 wt % hemicellulose-derived carbohydrate and less than 5% of a cellulase-inducing carbohydrate or contains from about 25 wt % to about 100% wt % hemicellulose-derived sugar alcohol in combination with from about 0 wt % to about 75 wt % glucose, glycerol or a combination thereof.Type: GrantFiled: November 3, 2009Date of Patent: December 4, 2012Assignee: Iogen Energy CorporationInventors: Loreta Gudynaite-Savitch, Christopher D. Hindle, Theresa C. White
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Publication number: 20110159560Abstract: The present invention relates to novel xylose-fermenting yeast strains (for example, yeast of the genus Saccharomyces, e.g., S. cerevisiae) with an enhanced ability to ferment the xylose (and/or another pentose sugar) present in a lignocellulosic hydrolysate to a fermentation product(s) (for example, an alcohol (e.g., ethanol) or a sugar alcohol (e.g., xylitol)).Type: ApplicationFiled: December 30, 2010Publication date: June 30, 2011Applicant: IOGEN ENERGY CORPORATIONInventors: Jennifer Donaldson, Jan-Maarten A. Geertman, Glenn D. Munkvold, Gary Pigeau, Philippe J. Dufresne, Loreta Gudynaite-Savitch
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Publication number: 20100129880Abstract: A fermentation process for the production of cellulase mixtures is provided. The process comprises providing a genetically modified host filamentous fungus that overexpresses a Xyr1 transcription factor and/or that is partially or completely deficient in expressing one or more hemicellulase enzyme. The host filamentous fungus is cultured in a medium comprising a carbon source. The carbon source contains from about 60 wt % to about 100 wt % hemicellulose-derived carbohydrate and less than 5% of a cellulase-inducing carbohydrate or contains from about 25 wt % to about 100% wt % hemicellulose-derived sugar alcohol in combination with from about 0 wt % to about 75 wt % glucose, glycerol or a combination thereof.Type: ApplicationFiled: November 3, 2009Publication date: May 27, 2010Applicant: IOGEN ENERGY CORPORATIONInventors: Loreta Gudynaite-Savitch, Christopher D. Hindle, Theresa C. White