Patents by Inventor Loretta A. Bober

Loretta A. Bober has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for treating atherosclerosis by administering human MCP1 fusions
    Patent number: 8282914
    Abstract: The present invention provides polypeptides including MCP1 fused, optionally, by a linker, to an immunoglobulin. Methods for using the polypeptides to treat medical disorders are also covered.
    Type: Grant
    Filed: May 2, 2011
    Date of Patent: October 9, 2012
    Assignee: Merck, Sharp & Dohme Corp.
    Inventors: Chuan-Chu Chou, Loretta A. Bober, Lee Sullivan
  • MCP1 FUSIONS
    Publication number: 20110206669
    Abstract: The present invention provides polypeptides including MCP1 fused, optionally, by a linker, to an immunoglobulin. Methods for using the polypeptides to treat medical disorders are also covered.
    Type: Application
    Filed: May 2, 2011
    Publication date: August 25, 2011
    Applicant: Schering Corporation
    Inventors: Chuan-Chu Chou, Loretta A. Bober, Lee Sullivan
  • Methods for treating rheumatoid arthritis and multiple sclerosis using MCP1 fusions
    Patent number: 7972591
    Abstract: The present invention provides polypeptides including MCP1 fused, optionally, by a linker, to an immunoglobulin. Methods for using the polypeptides to treat medical disorders are also covered.
    Type: Grant
    Filed: November 18, 2009
    Date of Patent: July 5, 2011
    Assignee: Schering Corporation
    Inventors: Chuan-Chu Chou, Loretta A. Bober, Lee Sullivan
  • Treatment of chemokine mediated diseases
    Patent number: 7960433
    Abstract: Methods of treating chemokine-mediated diseases are disclosed. The methods comprise the administration of CXC-Chemokine receptor antagonists of the formula or pharmaceutically acceptable salts or solvates thereof, in combination with other classes of pharmaceutical compounds. The chemokine-mediated diseases include acute and chronic inflammatory disorders, psoriasis, cystic fibrosis, asthma and cancer. Also disclosed are novel compounds of formula (I).
    Type: Grant
    Filed: February 14, 2007
    Date of Patent: June 14, 2011
    Assignee: Schering Corporation
    Inventors: Arthur G. Taveras, Motasim Billah, Daniel Lundell, William Kreutner, James Jakway, Jay S. Fine, Loretta A. Bober, Jianhua Chao, Purakkattle J. Biju, Younong Yu
  • MCP1 FUSIONS
    Publication number: 20100172904
    Abstract: The present invention provides polypeptides including MCP1 fused, optionally, by a linker, to an immunoglobulin. Methods for using the polypeptides to treat medical disorders are also covered.
    Type: Application
    Filed: November 18, 2009
    Publication date: July 8, 2010
    Inventors: Chuan-Chu Chou, Loretta A. Bober, Lee Sullivan
  • MCP1 fusions
    Patent number: 7713521
    Abstract: The present invention provides polypeptides including MCP1 fused, optionally, by a linker, to an immunoglobulin. Methods for using the polypeptides to treat medical disorders are also covered.
    Type: Grant
    Filed: August 10, 2006
    Date of Patent: May 11, 2010
    Assignee: Schering Corporation
    Inventors: Chuan-Chu Chou, Loretta A. Bober, Lee Sullivan
  • Treatment of chemokine mediated diseases
    Publication number: 20070155756
    Abstract: Methods of treating chemokine-mediated diseases are disclosed. The methods comprise the administration of CXC-Chemokine receptor antagonists of the formula or pharmaceutically acceptable salts or solvates thereof, in combination with other classes of pharmaceutical compounds. The chemokine-mediated diseases include acute and chronic inflammatory disorders, psoriasis, cystic fibrosis, asthma and cancer. Also disclosed are novel compounds of formula (I).
    Type: Application
    Filed: February 14, 2007
    Publication date: July 5, 2007
    Inventors: Arthur Taveras, Motasim Billah, Daniel Lundell, William Kreutner, James Jakway, Jay Fine, Loretta Bober, Jianhua Chao, Purakkattle Biju, Younong Yu
  • MCP1 fusions
    Publication number: 20070036750
    Abstract: The present invention provides polypeptides including MCP1 fused, optionally, by a linker, to an immunoglobulin. Methods for using the polypeptides to treat medical disorders are also covered.
    Type: Application
    Filed: August 10, 2006
    Publication date: February 15, 2007
    Inventors: Chuan-Chu Chou, Loretta Bober, Lee Sullivan
  • Treatment of chemokine mediated diseases
    Publication number: 20040053953
    Abstract: Methods of treating chemokine-mediated diseases are disclosed.
    Type: Application
    Filed: March 17, 2003
    Publication date: March 18, 2004
    Applicant: Schering Corporation
    Inventors: Arthur G. Taveras, Motasim Billah, Daniel Lundell, William Kreutner, James Jakway, Jay S. Fine, Loretta A. Bober, Jianhua Chao, Purakkattle J. Biju, Younong Yu
  • Naphthyridines which affect IL-4 and G-CSF
    Patent number: 5939431
    Abstract: Compounds of formula ##STR1## or pharmaceutically acceptable salts thereof, wherein E, Q, T, U, V, L, Z, X, W, M, Y and Y' are as set forth herein, are described. These compounds are useful as agents in the treatment of allergy, inflammation, autoimmune diseases, B-cell lymphomas, tumors, and the after effects of bone marrow transplantation.
    Type: Grant
    Filed: June 19, 1997
    Date of Patent: August 17, 1999
    Assignee: Schering Corporation
    Inventors: Daniel M. Solomon, Michael J. Grace, Jay S. Fine, Loretta A. Bober, Margaret H. Sherlock
  • Method for enhancing wound healing/repair with IL-4
    Patent number: 5723119
    Abstract: Disclosed are methods of enhancing the reparative phase of wound healing and repair in a mammal by administering to the wound site during the reparative phase an effective amount of IL-4. Also disclosed are methods of enhancing the healing and repair of infected wounds, wounds of diabetic mammals, and wounds of immunocompromised mammals by administering a therapeutically effective amount of IL-4 to the wound.
    Type: Grant
    Filed: May 25, 1995
    Date of Patent: March 3, 1998
    Assignee: Schering Corporation
    Inventors: Martin A. Schwarz, Lee M. Sullivan, Loretta A. Bober, Michael J. Grace