Patents by Inventor Loretta Sue Loesch-Fries

Loretta Sue Loesch-Fries has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nanoparticles and biotemplates with tunable length and methods of manufacturing the same
    Patent number: 11820988
    Abstract: Methods and nucleic acid sequences for the synthesis of biotemplates in a non-plant based expression system are provided. Such biotemplates include Barley stripe mosaic virus viral-like particles (BSMV-VLPs) that are capable of self-assembly due to being operatively linked with an origin of self-assembly with the Barley stripe mosaic virus capsid protein (BSMV-CP). Also provided are BSMV-VLPs that are capable of self-assembly due one or more site-directed mutations on the BSMV-CP, and BSMV-VLPs that exhibit enhanced stability due to such site-directed mutation(s).
    Type: Grant
    Filed: February 28, 2020
    Date of Patent: November 21, 2023
    Assignee: Purdue Research Foundation
    Inventors: Kevin Solomon, Kok Zhi Lee, Yu-Hsuan Lee, Michael Harris, Loretta Sue Loesch-Fries
  • NANOPARTICLES AND BIOTEMPLATES WITH TUNABLE LENGTH AND METHODS OF MANUFACTURING THE SAME
    Publication number: 20200277613
    Abstract: Methods and nucleic acid sequences for the synthesis of biotemplates in a non-plant based expression system are provided. Such biotemplates include Barley stripe mosaic virus viral-like particles (BSMV-VLPs) that are capable of self-assembly due to being operatively linked with an origin of self-assembly with the Barley stripe mosaic virus capsid protein (BSMV-CP). Also provided are BSMV-VLPs that are capable of self-assembly due one or more site-directed mutations on the BSMV-CP, and BSMV-VLPs that exhibit enhanced stability due to such site-directed mutation(s).
    Type: Application
    Filed: February 28, 2020
    Publication date: September 3, 2020
    Inventors: Kevin Solomon, Kok Zhi Lee, Yu-Hsuan Lee, Michael Harris, Loretta Sue Loesch-Fries