Patents by Inventor Lori Ann Birder

Lori Ann Birder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250127787
    Abstract: Methods for treating a peripheral neuropathy are disclosed herein. Methods are also disclosed for improving nerve function in a subject with a peripheral neuropathy. These methods use a PNPase inhibitor or a PNPase purine nucleoside substrate. These methods include selecting the subject with the peripheral neuropathy; and administering to the subject a therapeutically effective amount of a purine nucleoside phosphorylase (PNPase) inhibitor and/or a PNPase purine nucleoside substrate.
    Type: Application
    Filed: September 2, 2022
    Publication date: April 24, 2025
    Applicant: University of Pittsburgh - Of the Commonwealth System of Higher Education
    Inventors: Lori Ann Birder, Edwin Kerry Jackson, Amanda Sue Wolf-Johnston
  • Publication number: 20220054494
    Abstract: Methods of treating bladder or urethra dysfunction or disease in a subject and methods of increasing bladder smooth muscle contractility or increasing bladder wall volume in a subject are disclosed. In some examples, a purine nucleoside phosphorylase (PNPase) inhibitor or purine nucleoside substrate is administered, such as 8-aminoguanine or forodesine.
    Type: Application
    Filed: March 13, 2020
    Publication date: February 24, 2022
    Applicants: University of Pittsburgh - Of the Commonwealth System of Higher Education, Vanderbilt University, The Trustees of The University of Pennsylvania
    Inventors: Edwin Kerry Jackson, Lori Ann Birder, Amanda Sue Wolf-Johnston, Roger Dmochowski, Alan J. Wein