Patents by Inventor Lori Ann Schretzman

Lori Ann Schretzman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Platelet aggregation inhibitors
    Patent number: 5721366
    Abstract: This invention relates to compounds having the following formula ##STR1## or a pharmaceutically acceptable salt thereof which are useful in the inhibition of platelet aggregation, to pharmaceutical compositions of such phenylamidines derivatives, and to a method of inhibiting platelet aggregation in mammals by administering such compounds and compositions.
    Type: Grant
    Filed: May 23, 1995
    Date of Patent: February 24, 1998
    Assignee: G. D. Searle & Co
    Inventors: Norman Anthony Abood, Daniel Lee Flynn, Robert Bruce Garland, Lori Ann Schretzman, Kenneth Williams, Jeffery Alan Zablocki, Susan Landis Hockerman
  • Intermediates for amidino phenyl pyrrolidine .beta.-alanine urea analogs
    Patent number: 5659063
    Abstract: The invention herein is directed to a process for producing a lactam of the formula ##STR1## from a methionine analog of the formula ##STR2## by treating the methionine analog with trimethylsulfonium halide or trimethylsulfoxonium halide in the presence of a base in a suitable aprotic solvent.The invention herein is further directed to the preparation of amidinophenyl pyrrolidinyl .beta.-alanine urea analogs using such methionine and lactam compounds as intermediates, which .beta.-alanine urea analogs are useful as antithrombotics.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: August 19, 1997
    Assignee: G. D. Searle & Co.
    Inventors: Norman Anthony Abood, Daniel Lee Flynn, Scott Anthony Laneman, Roger Nosal, Lori Ann Schretzman