Patents by Inventor Lori Clarke

Lori Clarke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aqueous, non-alcoholic liquid powder formulations
    Patent number: 7455849
    Abstract: The present invention is an aqueous, non-alcoholic liquid powder formulation. The aqueous, non-alcoholic liquid powder formulation comprises from about 14% to about 75% by weight of the formulation of water, from about 25% to about 60% by weight of the formulation of a powder, from about 0.05% to about 1% by weight of the formulation of a polymeric emulsifier, from about 0.5% to about 15% by weight of the formulation of a low molecular weight silicone wherein the low molecular weight silicone has an average molecular weight of about 10,000 or less, and from about 0.1% to about 10% by weight of the formulation of a high molecular weight silicone wherein the high molecular weight silicone has an average molecular weight of about 100,000 or greater. The aqueous, non-alcoholic liquid powder formulation may have an optical uniformity index of about 0.1 or less. The aqueous, non-alcoholic liquid powder formulation may have an extensive uniformity index of about 300 or greater.
    Type: Grant
    Filed: September 16, 2004
    Date of Patent: November 25, 2008
    Assignee: Kimberly-Clark Worldwide, Inc.
    Inventors: Julie Marie Utschig, Keisha Lori Clarke, Wael Rafat Joseph, David William Koenig, Duane Gerard Krzysik
  • Vector constructs
    Patent number: 7109029
    Abstract: The present invention provides novel viral vectors and methods useful for the minimization of leaky gene expression, and, in particular, of nonspecific transcriptional read-through of genes. Such constructs may be obtained by the insertion of an insulating sequence into a vector construct, such as for example a termination signal sequence upstream of the transcription initiation site of the respective transcription unit.
    Type: Grant
    Filed: February 22, 2002
    Date of Patent: September 19, 2006
    Assignee: Cell Genesys, Inc.
    Inventors: Lori Clarke, Mario Gorziglia, Paul L. Hallenbeck, John Leonard Jakubczak, Michael Kaleko, Sandrina Phipps
  • Novel vector constructs
    Publication number: 20030104624
    Abstract: The present invention provides novel viral vectors and methods useful for the minimization of leaky gene expression, and, in particular, of nonspecific transcriptional read-through of genes. Such constructs may be obtained by the insertion of an insulating sequence into a vector construct, such as for example a termination signal sequence upstream of the transcription initiation site of the respective transcription unit.
    Type: Application
    Filed: February 22, 2002
    Publication date: June 5, 2003
    Inventors: Lori Clarke, Mario Gorziglia, Paul L. Hallenbeck, John Leonard Jakubczak, Michael Kaleko, Sandrina Phipps
  • Novel oncolytic adenoviral vectors
    Publication number: 20030104625
    Abstract: The present invention relates to oncolytic adenoviral vectors and their use in methods of gene therapy. Provided is a recombinant viral vector comprising an adenoviral nucleic acid backbone, wherein said nucleic acid backbone comprises in sequential order: A left ITR, a termination signal sequence, an E2F responsive promoter which is operably linked to a gene essential for replication of the recombinant viral vector, an adenoviral packaging signal, and a right ITR.
    Type: Application
    Filed: February 22, 2002
    Publication date: June 5, 2003
    Inventors: Cheng Cheng, Lori Clarke, Sheila Connelly, David Leonard Ennist, Suzanne Forry-Schaudies, Mario Gorziglia, Paul L. Hallenbeck, Carl M. Hay, John Leonard Jakubczak, Michael Kaleko, Sandrina Phipps, Seshidhar Reddy Police, Patricia Clare Ryan, David A. Stewart, Yuefeng Xie