Patents by Inventor Lori Manzel

Lori Manzel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antagonism of immunostimulatory CpG-oligonucleotides by 4-aminoquinolines and other weak bases
    Patent number: 6479504
    Abstract: The present invention relates generally to the field of immunology. More particularly it concerns compositions and methods for inhibiting stimulation of the immune system. The compounds and methods comprise compounds that are analogs and derivatives of chloroquine, such as 4-aminoquinolines, and other weak bases. They can be used in preventative and therapeutic treatments of autoimmune diseases and phenomena, transplant rejection such as host-versus-graft disease, and sepsis.
    Type: Grant
    Filed: June 16, 2000
    Date of Patent: November 12, 2002
    Assignees: The University of Iowa Research Foundation, Georgia State University Research Foundation, Inc., The United States of America as represented by the Department of Veterans Affairs
    Inventors: Donald E. Macfarlane, Lucjan Strekowski, Lori Manzel, Fyaz M. D. Ismail, Gordon B. Barlin