Abstract: An embodiment of a cell-oxygenation monitoring system includes a probe and a base. The probe is connectable to the base, configured to direct electromagnetic energy having wavelengths in an approximate range of 400 nm-900 nm into a body having at least one cell, and configured to receive a portion of the electromagnetic energy redirected by the body during a time. The base includes a generator configured to generate the electromagnetic energy during the time, and a computing circuit configured to determine, in response to the portion of redirected electromagnetic energy, a level of oxygenation of one or more of the at least one cell.

Abstract: An embodiment of a cell-oxygenation monitoring system includes a probe and a base. The probe is connectable to the base, configured to direct electromagnetic energy having wavelengths in an approximate range of 400 nm-900 nm into a body having at least one cell, and configured to receive a portion of the electromagnetic energy redirected by the body during a time. The base includes a generator configured to generate the electromagnetic energy during the time, and a computing circuit configured to determine, in response to the portion of redirected electromagnetic energy, a level of oxygenation of one or more of the at least one cell.

Abstract: A system and method for noninvasively determining the oxygenation of a tissue, for example, a muscle, in vivo uses optical methods to optically interrogate the tissue in both a visible wavelength range and a near infrared (NIR) wavelength range. The illuminating light is sculpted in intensity to approximately match the absorbance spectrum, for example, with the visible light having an intensity an order of magnitude greater than the NIR light. Training data is obtained from healthy patients in both the visible and NIR ranges simultaneously and used to calculate muscle oxygenation.

Abstract: A system and method for noninvasively determining the oxygenation of a tissue, for example, a muscle, in vivo uses optical methods to optically interrogate the tissue in both a visible wavelength range and a near infrared (NIR) wavelength range. The illuminating light is sculpted in intensity to approximately match the absorbance spectrum, for example, with the visible light having an intensity an order of magnitude greater than the NIR light. Training data is obtained from healthy patients in both the visible and NIR ranges simultaneously and used to calculate muscle oxygenation.

Abstract: A system and method for noninvasively determining the oxygenation of a tissue, for example, a muscle, in vivo uses optical methods to optically interrogate the tissue in both a visible wavelength range and a near infrared (NIR) wavelength range. The illuminating light is sculpted in intensity to approximately match the absorbance spectrum, for example, with the visible light having an intensity an order of magnitude greater than the NIR light. Training data is obtained from healthy patients in both the visible and NIR ranges simultaneously and used to calculate muscle oxygenation.

Abstract: A system and method for noninvasively determining the oxygenation of a tissue, for example, a muscle, in vivo uses optical methods to optically interrogate the tissue in both a visible wavelength range and a near infrared (NIR) wavelength range. The illuminating light is sculpted in intensity to approximately match the absorbance spectrum, for example, with the visible light having an intensity an order of magnitude greater than the light. Training data is obtained from healthy patients in both the visible and NIR ranges simultaneously and used to calculate muscle oxygenation.

Abstract: This document describes, among other things, monitoring of intracellular oxygenation using an optical probe coupled to a multi-wavelength spectrometer. Multivariate analysis of the spectrum data yields quantifiable cellular characteristics.