Abstract: A fluid collection device has a collection vial with a reservoir chamber for receiving a fluid sample. An elongated expresser is disposed within the collection via, which includes a fluid permeable base enabling passage of fluid sample into the reservoir chamber. A fluid test card is supported by an expresser bottom flange within the collection vial and a plunger is provided for compression of a swab saturated with fluid specimen into the reservoir chamber. A cap is provided for engaging the collection vial in order to seal the compressor, fluid test card, compressed swab, and plunger within the collection vial.