Patents by Inventor Lorne J. Hofseth

Lorne J. Hofseth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detecting Protein Arginine Deiminase (PAD) Activity in Human Tissues and Sera
    Publication number: 20120295292
    Abstract: Methods for diagnosing disease that is characterized by an overabundance of citrullinated proteins such as colitis, rheumatoid arthritis, and/or malignant cancer in a subject are provided. The PAD protein activity level can be measured in a tissue sample (e.g., serum) of the subject and then compared to a control PAD protein activity range of a control group. A finding of an increased PAD protein activity level in the tissue sample of the subject compared to the PAD protein activity level of the control group is indicative of disease characterized by an overabundance of citrullinated proteins in the subject.
    Type: Application
    Filed: May 21, 2012
    Publication date: November 22, 2012
    Applicant: University of South Carolina
    Inventors: Paul R. Thompson, Lorne J. Hofseth, Bryan A. Knuckley