Patents by Inventor Lorne Palmer

Lorne Palmer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lipid formulations for nucleic acid delivery
    Patent number: 8058069
    Abstract: The present invention provides novel, stable lipid particles comprising one or more active agents or therapeutic agents, methods of making the lipid particles, and methods of delivering and/or administering the lipid particles. More particularly, the present invention provides stable nucleic acid-lipid particles (SNALP) comprising a nucleic acid (such as one or more interfering RNA), methods of making the SNALP, and methods of delivering and/or administering the SNALP.
    Type: Grant
    Filed: April 15, 2009
    Date of Patent: November 15, 2011
    Assignee: Protiva Biotherapeutics, Inc.
    Inventors: Edward Yaworski, Kieu Lam, Lloyd Jeffs, Lorne Palmer, Ian MacLachlan
  • Compositions comprising immunostimulatory siRNA molecules and DLinDMA or DLenDMA
    Patent number: 7807815
    Abstract: The present invention provides siRNA molecules and methods of using such siRNA molecules to modulate an immune response and to silence expression of a target gene.
    Type: Grant
    Filed: June 30, 2005
    Date of Patent: October 5, 2010
    Assignee: Protiva Biotherapeutics, Inc.
    Inventors: Ian MacLachlan, Adam Judge, James Heyes, Lorne Palmer
  • NOVEL LIPID FORMULATIONS FOR NUCLEIC ACID DELIVERY
    Publication number: 20100130588
    Abstract: The present invention provides novel, stable lipid particles comprising one or more active agents or therapeutic agents, methods of making the lipid particles, and methods of delivering and/or administering the lipid particles. More particularly, the present invention provides stable nucleic acid-lipid particles (SNALP) comprising a nucleic acid (such as one or more interfering RNA), methods of making the SNALP, and methods of delivering and/or administering the SNALP.
    Type: Application
    Filed: April 15, 2009
    Publication date: May 27, 2010
    Applicant: Protiva Biotherapeutics, Inc.
    Inventors: Edward Yaworski, Kieu Lam, Lloyd Jeffs, Lorne Palmer, Ian MacLachlan
  • siRNA silencing of genes expressed in cancer
    Publication number: 20090149403
    Abstract: The present invention provides nucleic acid-lipid particles comprising siRNA molecules that silence genes expressed in cancer (e.g., Eg5, EGFR or XIAP) and methods of using such nucleic acid-lipid particles to silence Eg5, EGFR or XIAP gene expression.
    Type: Application
    Filed: May 29, 2007
    Publication date: June 11, 2009
    Applicant: Protiva Biotherapeutics, Inc.
    Inventors: Ian MacLachlan, Adam Judge, Vandana Sood, James Heyes, Lloyd B. Jeffs, Lorne Palmer
  • siRNA silencing of apolipoprotein B
    Publication number: 20060134189
    Abstract: The present invention provides nucleic acid-lipid particles comprising siRNA molecules that silence ApoB expression and methods of using such nucleic acid-lipid particles to silence ApoB expression.
    Type: Application
    Filed: November 17, 2005
    Publication date: June 22, 2006
    Applicant: Protiva Biotherapeutics, Inc
    Inventors: Ian MacLachlan, Lloyd Jeffs, Adam Judge, Amy Lee, Lorne Palmer, Vandana Sood
  • Cationic lipids and methods of use
    Publication number: 20060083780
    Abstract: The present invention provides compositions comprising cationic lipids, liposomes and nucleic acid-lipid particles comprising the cationic lipids, and methods of using such compositions, liposomes, and nucleic acid-lipid particles.
    Type: Application
    Filed: June 7, 2005
    Publication date: April 20, 2006
    Applicant: Protiva Biotherapeutics, Inc.
    Inventors: James Heyes, Ian MacLachlan, Lorne Palmer
  • Lipid encapsulated interfering RNA
    Publication number: 20060008910
    Abstract: The present invention provides lipid-based formulations for delivering, e.g., introducing, nucleic acid-lipid particles comprising an interference RNA molecule to a cell, and assays for optimizing the delivery efficiency of such lipid-based formulations.
    Type: Application
    Filed: June 7, 2005
    Publication date: January 12, 2006
    Applicant: Protiva Biotherapeuties, Inc.
    Inventors: Ian MacLachlan, Lorne Palmer, James Heyes