Abstract: The present invention provides a pharmaceutical composition comprising at least one pharmaceutically acceptable bismuth-containing compound, at least one pharmaceutically acceptable non-clay-derived suspending agent, and water. The suspension exhibits reduced upward pH drift by comparison with an otherwise similar suspension which comprises a clay-derived suspending agent. Such compositions are useful in the prevention and treatment of gastrointestinal diseases and/or disorders.

Abstract: The present invention provides a pharmaceutical composition comprising at least one pharmaceutically acceptable bismuth-containing compound, at least one pharmaceutically acceptable non-clay-derived suspending agent, and water. The suspension exhibits reduced upward pH drift by comparison with an otherwise similar suspension which comprises a clay-derived suspending agent. Such compositions are useful in the prevention and treatment of gastrointestinal diseases and/or disorders.

Abstract: There is provided a pharmaceutical composition suitable for rectal administration, the composition comprising at least one oxazolidinone antibacterial drug, for example linezolid, in a concentration effective for treatment and/or prophylaxis of a gram-positive bacterial infection, the at least one oxazolidinone being in particulate form having a particle size of about 0.5 &mgr;m to about 150 &mgr;m, dispersed in a carrier in which the oxazolidinone is poorly soluble. The composition is, for example, a suppository, an enema, a microenema or a rectal capsule.

Abstract: A suppository composition and method for rectal administration of a lincosamide antibacterial drug, such as clindamycin, lincomycin, or pirlimycin, is disclosed. The composition is a rectal suppository containing an antimicrobially effective amount of the lincosamide in particulate form dispersed in a Hard Fat suppository base, preferably a Hard Fat NF suppository base. The most preferred suppository compositions of the present invention have long term storage stability, while maintaining effectiveness against bacterial infections.

Abstract: The present invention provides a novel pharmaceutically acceptable gel containing minoxidil for topical application.

Abstract: A conditioning shampoo formulation comprising a base surfactant level of at least 16%, which includes cocamidopropyl betaine and cocamide diethanolamine. The formulation is essentially free of additional preservatives and is suitable for use as a conditioner for hair prior to treatment with a hair restoring medication or agent.