Patents by Inventor Lorraine WORK

Lorraine WORK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Succinate dehydrogenase inhibitors (SDHi's)
    Patent number: 10603298
    Abstract: The invention relates to a succinate dehydrogenase inhibitor or a prodrug and/or a pharmaceutically acceptable salt thereof for use in the treatment or prevention of reperfusion injury, such as ischemia-reperfusion injury, by inhibiting the accumulation of succinate, wherein the inhibitor or prodrug and/or pharmaceutically acceptable salt thereof is a cell-permeable reversible inhibitor of succinate dehydrogenase.
    Type: Grant
    Filed: July 3, 2015
    Date of Patent: March 31, 2020
    Inventors: Edward Chouchani, Thomas Krieg, Michael Patrick Murphy, Lorraine Work, Christian Frezza, Kourosh Saeb-Parsy
  • SUCCINATE DEHYDROGENASE INHIBITORS (SDHI's)
    Publication number: 20170135977
    Abstract: The invention relates to a succinate dehydrogenase inhibitor or a prodrug and/or a pharmaceutically acceptable salt thereof for use in the treatment or prevention of reperfusion injury, such as ischemia-reperfusion injury, by inhibiting the accumulation of succinate, wherein the inhibitor or prodrug and/or pharmaceutically acceptable salt thereof is a cell-permeable reversible inhibitor of succinate dehydrogenase.
    Type: Application
    Filed: July 3, 2015
    Publication date: May 18, 2017
    Inventors: Edward CHOUCHANI, Thomas KRIEG, Michael Patrick MURPHY, Lorraine WORK, Christian FREZZA