Patents by Inventor Lorrine A. Chao

Lorrine A. Chao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • C-erbB-2 external domain: gp75
    Publication number: 20060019344
    Abstract: Disclosed are methods and compositions for identifying malignant tumors that overexpress the c-erbB-2 oncogene. Assays useful for diagnosis and prognosis of neoplastic disease are provided which detect the external domain of c-erbB-2, the glycoprotein gp75 and quantitate the level of gp75 in the biological fluids of mammals carrying a tumor burden. Further disclosed are recombinant, synthetically and otherwise biologically produced novel proteins and polypeptides which are encoded by the external domain DNA sequence of the c-erbB-2 oncogene (the gp75 gene) or fragments thereof. Such gp75 proteins and polypeptides are useful as vaccines, therapeutically in the treatment of cancer either alone or in combination with chemotherapeutic agents. Also disclosed are antibodies to such gp75 proteins and polypeptides which are useful diagnostically and therapeutically. Still further disclosed are test kits embodying the assays of this invention.
    Type: Application
    Filed: July 7, 2005
    Publication date: January 26, 2006
    Inventors: Susan Stuart, John Monahan, Beatrice Langton, Miriam Hancock, Lorrine Chao, Peter Bluford
  • C-erbB-2 exrernal domain: gp75
    Publication number: 20020155527
    Abstract: Disclosed are methods and compositions for identifying malignant tumors that overexpress the c-erbB-2 oncogene. Assays useful for diagnosis and prognosis of neoplastic disease are provided which detect the external domain of c-erbB-2, the glycoprotein gp75 and quantitate the level of gp75 in the biological fluids of mammals carrying a tumor burden.
    Type: Application
    Filed: January 26, 2001
    Publication date: October 24, 2002
    Applicant: Triton BioSciences, Inc.
    Inventors: Susan G. Stuart, John J. Monahan, Beatrice Claudia Langton, Miriam E. C. Hancock, Lorrine A. Chao, Peter Bluford