Patents by Inventor Lothar Beutin

Lothar Beutin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for detecting and identifying enterohemorrhagic
    Patent number: 10190175
    Abstract: The invention relates to methods for predicting whether a sample contains enterohemorrhagic Escherichia coli (EHEC) of at least one of EHEC O157:[H7], O145:[H28], O103:[H2], O111:[H8], O121:[H19], O26: [H11], O45:[H2] or O104: [H4] serotypes, and for identifying said serotypes, through detection of gene espK in association with at least one of the genetic markers Z1151, Z1153, Z1154, Z1155, Z1156, Z6065, Z2098, ureD or espV and/or through detection of serotype-specific CRISPR sequences.
    Type: Grant
    Filed: June 14, 2013
    Date of Patent: January 29, 2019
    Assignees: Agence Nationale de Securite Sanitaire de l'Alimentation, de l'Environnement et due Travail, Bundesinstitut Fur Risikobewertung
    Inventors: Patrick Fach, Sabine Delannoy, Lothar Beutin
  • Assay for determining a molecular risk assessment of a complex polymicrobial sample suspected to contain an EHEC
    Patent number: 9416425
    Abstract: The present invention relates to a process to perform a molecular risk assessment (MRA) upon a sample suspected to contain an enterohemorrhagic Escherichia coli (EHEC), comprising the steps: contacting said sample or DNA isolated therefrom with a pair of primers derived from the following target genes stx1, stx2, eae and/or espk; wherein the process is characterized in that if amplification products are detected for each of the target genes in the first step, in a second step said sample or DNA isolated therefrom is contacted with a pair of primers derived from the following target genes nleB, nleH1-2, nleE, ent/espL2, eae subtypes ?, ?, ? and ? and the target genes rfbE (0157), wbdl (0111), wzx (026); ihp1 (0145), wzx (0103); and detecting the presence or the absence of an amplification product for each of the target genes.
    Type: Grant
    Filed: August 11, 2010
    Date of Patent: August 16, 2016
    Assignee: Agence Nationale de Securite Sanitaire de l'Alimentation, de l'Environment et du Travail
    Inventors: Patrick Fach, Marie Bugarel, Lothar Beutin
  • Method for Detecting and Identifying Enterohemorrhagic Escherichia coli
    Publication number: 20150176064
    Abstract: The invention relates to methods for predicting whether a sample contains enterohemorrhagic Escherichia coli (EHEC) of at least one of EHEC O157:[H7], O145:[H28], O103:[H2], O111:[H8], O121:[H19], O26: [H11], O45:[H2] or O104: [H4] serotypes, and for identifying said serotypes, through detection of gene espK in association with at least one of the genetic markers Z1151, Z1153, Z1154, Z1155, Z1156, Z6065, Z2098, ureD or espV and/or through detection of serotype-specific CRISPR sequences.
    Type: Application
    Filed: June 14, 2013
    Publication date: June 25, 2015
    Applicants: Agence Nationale de Securite Sanitaire de I'Alimentation, de I'Environnement et du Travail, Bundesinstiful Fur Risikobewertung
    Inventors: Patrick Fach, Sabine Delannoy, Lothar Beutin
  • Assay for Determining a Molecular Risk Assessment of a Complex Polymicrobial Sample Suspected to Contain an EHEC
    Publication number: 20120202204
    Abstract: The present invention relates to a process to perform a molecular risk assessment (MRA) upon a sample suspected to contain an enterohemorrhagic Escherichia coli (EHEC), comprising the steps: contacting said sample or DNA isolated therefrom with a pair of primers derived from the following target genes stx1, stx2, eae and/or espk; wherein the process is characterised in that if amplification products are detected for each of the target genes in the first step, in a second step said sample or DNA isolated therefrom is contacted with a pair of primers derived from the following target genes nleB, nleH1-2, nleE, ent/espL2, eae subtypes ?, ?, ? and ? and the target genes rfbE (0157), wbdl (0111), wzx (026); ihp1 (0145), wzx (0103); and detecting the presence or the absence of an amplification product for each of the target genes.
    Type: Application
    Filed: August 11, 2010
    Publication date: August 9, 2012
    Inventors: Patrick Fach, Marie Bugarel, Lothar Beutin