Patents by Inventor Lothar GREMER

Lothar GREMER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the quantitative characterization of amyloid and/or aggregating peptides and/or proteins in a sample
    Patent number: 10088487
    Abstract: A method for the quantitative characterization of amyloid and/or aggregated peptides and/or proteins in a sample, comprising:—providing a sample, wherein the sample includes an amyloid and/or aggregated peptide and/or protein having at least one aggregate size and shape;—adding an active ingredient to be analyzed to the sample solution;—separating the amyloid and/or aggregated peptides and/or proteins are from one another according to their aggregate size and shape;—optionally completely denaturing the amyloid and/or aggregated peptides and/or proteins of a particular fraction into monomer building blocks;—determining the change in concentration of the peptide and/or protein building blocks in at least one fraction by comparison against control values without the active ingredient.
    Type: Grant
    Filed: June 25, 2014
    Date of Patent: October 2, 2018
    Assignee: Forschungszentrum Juelich GmbH
    Inventors: Luitgard Nagel-Steger, Oleksandr Brener, Lothar Gremer, Dieter Willbold
  • METHOD FOR THE QUANTITATIVE CHARACTERIZATION OF AMYLOID AND/OR AGGREGATING PEPTIDES AND/OR PROTEINS IN A SAMPLE
    Publication number: 20160349273
    Abstract: A method for the quantitative characterization of amyloid and/or aggregated peptides and/or proteins in a sample, comprising: providing a sample, wherein the sample includes an amyloid and/or aggregated peptide and/or protein having at least one aggregate size and shape; adding an active ingredient to be analyzed to the sample solution; separating the amyloid and/or aggregated peptides and/or proteins are from one another according to their aggregate size and shape; optionally completely denaturing the amyloid and/or aggregated peptides and/or proteins of a particular fraction into monomer building blocks; determining the change in concentration of the peptide and/or protein building blocks in at least one fraction by comparison against control values without the active ingredient.
    Type: Application
    Filed: June 25, 2014
    Publication date: December 1, 2016
    Inventors: Luitgard NAGEL_STEGER, Oleksandr BRENER, Lothar GREMER, Dieter WILLBOLD