Patents by Inventor Lothar Halmer

Lothar Halmer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for reducing ligand leakage from affinity chromatography matrices
    Publication number: 20030148540
    Abstract: The present invention relates to a process for (pre)treating affinity chromatography matrices, preferably protein A matrices, with at least one surfactant for reducing ligand leakage. By treating the affinity chromatography matrix according to the invention it is possible to achieve an affinity chromatography matrix of constant quality in terms of ligand leakage, which is an important prerequisite for its suitability or use in biopharmaceutical processes. The present invention further relates to methods for determining the ligand leakage.
    Type: Application
    Filed: November 15, 2002
    Publication date: August 7, 2003
    Applicant: Boehringer Ingelheim Pharma KG
    Inventors: Lothar Halmer, Margit Holzer