Patents by Inventor Lothar Jäger

Lothar Jäger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Graminae pollen allergen mutants for specific immunotherapy, and production and use of the same
    Patent number: 6919086
    Abstract: The invention relates to modified recombinant allergen mutants which can be obtained from recombinant allergens which are derived from allergens which can be obtained by extraction from natural raw materials such as pollen of the species Phleum pratense. While these modified recombinant allergens stimulate lymphocytes from patients who are allergic to pollent to proliferate and synthesize cytokines, they exhibit a markedly diminished ability to bind to the IgE antibodies which are present in the serum of the T lymphocyte donors and to grass pollen allergen-specific IgEs and can therefore be used for a specific, made-to-release allergy therapy.
    Type: Grant
    Filed: March 16, 1998
    Date of Patent: July 19, 2005
    Assignee: Merck Patent Gesellschaft mit
    Inventors: Helga Kahlert, Hans-Thomas Stüwe, Helmut Fiebig, Oliver Cromwell, Wolf-Meinhard Becker, Albrecht Bufe, Gabriele Schramm, Lothar Jäger, Wolf-Dieter Müller