Abstract: Implant provided with a coating, with the implant being provided with an amino-functionalized parylene coating, an oligonucleotide and/or an oligopeptide having a specific bonding affinity with CD34-positive cells.

Abstract: Implant provided with a coating, with the implant being provided with an amino-functionalized parylene coating, an oligonucleotide and/or an oligopeptide having a specific bonding affinity with CD34-positive cells.

Abstract: The invention relates to a medical device with a base body and a coating, wherein the coating exhibits film or lacquer-forming terpenoids. In addition, the coating of the medical device can exhibit at least one application-specific additive. The invention further relates to a method for manufacturing such a device.

Abstract: A biocompatible material comprising a substrate made of a polyolefin material, and having a coating of biocompatible carbon material, wherein the coating is obtained by a process comprising the following steps:introducing a preformed substrate into an atmosphere of gaseous monomer vinylidene chloride (1,1 di-chloro ethylene);inducing a graft-polymerization reaction and grafting a uniform layer of polyvinylidene chloride on the substrate; andsubstantially eliminating and removing hydrogen chloride (dehydrochlorination reaction) from the polyvinylidene chloride in order to convert the polyvinylidene chloride layer into a coating of biocompatible carbon material.

Abstract: A biocompatible porous hollow fiber made of a polyolefine material and having a coating of biocompatible carbon material herein said coating is obtainable by a process comprising the following steps:introducing a preformed porous hollow fiber into an atmosphere of gaseous monomer vinylidene chloride (1,1 di-chloroethylene);inducing a graft-polymerization reaction and grafting a uniform layer of polyvinylidene chloride on the polyolefine material forming said porous hollow fiber; andsubstantially eliminating and removing hydrogene chloride (dehydrochlorination reaction) from said polyvinylidene chloride in order to convert said polyvinylidene chloride layer into a coating of biocompatible carbon material.Preferably said graft-polymerization reaction may be induced by means of an ionizing radiation, especially by means of a gamma radiation. Preferably said substantial removal of hydrogene chloride may be performed by treating the coated hollow fiber with a hot concentrated aqueous ammonia solution.

Abstract: A process of making a biocampatible porous hollow fiber that is made of polyolefine material and is coated with a biocompatible carbon material is disclosed. The biocompatible hollow fiber produced can be used as exchange material, diaphragms and/or semipermeable membranes within devices which will contact blood or plasma outside of the living body. The coated fiber is produced by introducing a preformed porous hollow fiber into an atmosphere of gaseous monomer vinylidene chloride and subsequent induction, e.g. by gamma radiation, of a graft-polymerization reaction to form an uniform polyvinylidene chloride layer. The ultimate coating is formed after a dehydrochlorination reaction in which hydrogen chloride is removed from the layer. The dechlorination reaction is typically performed by treating the fiber with hot concentrated aqueous ammonia solution. The reaction can be continued to reduce the chlorine content of the coating to less than 6% of its original value.

Abstract: A biocompatible porous hollow fiber made of a polyolefin material and having a coating of biocompatible carbon material wherein the coating is obtained by a process comprising the following steps:introducing a preformed porous hollow fiber into an atmosphere of gaseous monomer vinylidene chloride (1,1 di-chloro ethylene);inducing a graft-polymerization reaction and grafting a uniform layer of polyvinylidene chloride on the polyolefin material forming the porous hollow fiber; andsubstantially eliminating and removing hydrogen chloride (dehydrochlorination reaction) from the polyvinylidene chloride in order to convert the polyvinylidene chloride layer into a coating of biocompatible carbon material.