Patents by Inventor Loui Thomas Madakamutil

Loui Thomas Madakamutil has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PYRAZINO[2,3-b]PYRAZINE mTOR KINASE INHIBITORS FOR ONCOLOGY INDICATIONS AND DISEASES ASSOCIATED WITH THE mTOR/PI3K/AKT PATHWAY
    Publication number: 20230119470
    Abstract: Provided herein are Heteroaryl Compounds having the following structure: wherein R1-R4 are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, neurodegenerative diseases, diabetes, obesity, neurological disorders, age-related diseases, or cardiovascular conditions, comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.
    Type: Application
    Filed: February 25, 2022
    Publication date: April 20, 2023
    Inventors: Jan ELSNER, Kimberly E. Fultz, Roy L. HARRIS, III, Branden Gingsee LEE, Loui Thomas Madakamutil, Deborah S. Mortensen, Rama Krishna Narla, Garrick K. PACKARD, Patrick PAPA, Jason PARNES, Sophie Perrin-Ninkovic, Jennifer RIGGS, Sabita SANKAR, John J. Sapienza, Graziella I. Shevlin, Lida Tehrani, Weiming XU, Jingjing ZHAO