Patents by Inventor Louis B. Nabors

Louis B. Nabors has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RNA-BINDING PROTEIN MULTIMERIZATION INHIBITORS AND METHODS OF USE THEREOF
    Publication number: 20230159542
    Abstract: This disclosure provides compounds that inhibit RNA-binding proteins, such as Human antigen R protein (HuR). The compounds described herein have a high affinity for HuR multimers and inhibit the pathological processes that promote cancer and inflammation. The compounds are highly water-soluble and have good biodistribution for both systemic and central nervous system disease processes. The compounds provide a unique therapeutic option for disease processes related to neoplastic progression or acute or chronic inflammation.
    Type: Application
    Filed: April 21, 2021
    Publication date: May 25, 2023
    Applicants: THE UAB RESEARCH FOUNDATION, SOUTHERN RESEARCH INSTITUTE, THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
    Inventors: Louis B. Nabors, Natalia Filippova, Xiuhua Yang, Subramaniam Ananthan, Vibha Pathak, Peter King