Patents by Inventor Louis C. Sehl

Louis C. Sehl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CRYSTALLINE TRIPEPTIDE EPOXY KETONE PROTEASE INHIBITORS
    Publication number: 20100240903
    Abstract: The invention relates to crystalline tripeptide keto epoxide compounds, methods of their preparation, and related pharmaceutical compositions.
    Type: Application
    Filed: March 22, 2010
    Publication date: September 23, 2010
    Applicant: Onyx Therapeutics, Inc.
    Inventors: Pasit Phiasivongsa, Louis C. Sehl
  • ADHESIVE TISSUE REPAIR PATCH AND COLLAGEN SHEETS
    Publication number: 20100233246
    Abstract: The present invention relates generally to synthetic polymer compositions that form interpenetrating polymer networks. In a preferred embodiment, the compositions comprise two multifunctionally activated synthetic polymers, along with a tensile strength enhancer. Such compositions form matrices that exhibit superior cohesive strength and in many instances can serve as adequate replacements for surgical means of attaching tissues, such as sutures, sponges and medical staples.
    Type: Application
    Filed: May 25, 2010
    Publication date: September 16, 2010
    Applicant: ANGIOTECH PHARMACEUTICALS (US), INC.
    Inventors: Louis C. Sehl, Olof Mikael Trollsas, Donald G. Wallace, David Toman, Frank A. DeLustro, Jacqueline A. Schroeder, George H. Chu
  • Crystalline peptide epoxy ketone protease inhibitors and the synthesis of amino acid keto-epoxides
    Publication number: 20090105156
    Abstract: The invention relates to crystalline peptide keto epoxide compounds, methods of their preparation, and related pharmaceutical compositions. This invention also relates to methods for the preparation of amino acid keto-epoxides. Specifically, allylic ketones are stereoselectively converted to the desired keto epoxides.
    Type: Application
    Filed: October 3, 2008
    Publication date: April 23, 2009
    Applicant: Proteolix, Inc.
    Inventors: Pasit Phiasivongsa, Louis C. Sehl, William Dean Fuller, Guy J. Laidig
  • Methods for tissue repair using adhesive materials
    Patent number: 6833408
    Abstract: A method of tissue repair is provided using a biocompatible nonimmunogenic adhesive composition. The adhesive composition comprises collagen and a plurality of crosslinkable components having reactive functional groups thereon, with the functional groups selected so as to enable inter-reaction between the components, i.e., crosslinking. Kits for use in carrying out the method of the invention are also provided, as are pretreated surgically acceptable patches that have been coated with the aforementioned adhesive composition.
    Type: Grant
    Filed: September 30, 2002
    Date of Patent: December 21, 2004
    Assignee: Cohesion Technologies, Inc.
    Inventors: Louis C. Sehl, Olof Mikael Trollsas, Donald G. Wallace, David Toman, Frank A. DeLustro, Jacqueline A. Schroeder, George H. Chu
  • Methods for tissue repair using adhesive materials
    Publication number: 20030119985
    Abstract: A method of tissue repair is provided using a biocompatible nonimmunogenic adhesive composition. The adhesive composition comprises collagen and a plurality of crosslinkable components having reactive functional groups thereon, with the functional groups selected so as to enable inter-reaction between the components, i.e., crosslinking. Kits for use in carrying out the method of the invention are also provided, as are pretreated surgically acceptable patches that have been coated with the aforementioned adhesive composition.
    Type: Application
    Filed: September 30, 2002
    Publication date: June 26, 2003
    Inventors: Louis C. Sehl, Olof Mikael Trollsas, Donald G. Wallace, David Toman, Frank A. DeLustro, Jacqueline A. Schroeder, George H. Chu
  • Ecarin prothrombin protease and methods
    Patent number: 6413737
    Abstract: New forms of ecarin, a procoagulant protein from Echis carinatus venom, are described, as are polynucleotides encoding the new proteins, methods for production of the new proteins, and methods for activation of prothrombin using the new proteins. The new ecarins comprise a serine at position 396 of the protein. The new proteins may be used for activation of prothrombin, and are particularly useful for the production of recombinant thrombin.
    Type: Grant
    Filed: June 30, 2000
    Date of Patent: July 2, 2002
    Assignee: Cohesion Technologies, Inc.
    Inventors: David R. Olsen, Jeff Prior, Louis C. Sehl, Donald G. Wallace