Patents by Inventor Louis Desantis, Jr.

Louis Desantis, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of beta-adrenoceptor antagonists for the manufacture of a medicament of the treatment of disorders of the outer retina
    Patent number: 8710102
    Abstract: Compositions and methods for treating disorders of the outer retina with ?-adrenoceptor antagonists are disclosed.
    Type: Grant
    Filed: June 9, 2010
    Date of Patent: April 29, 2014
    Assignee: Novartis AG
    Inventors: Robert J. Collier, Jr., Michael A. Kapin, Louis DeSantis, Jr.
  • Use of Beta-Adrenoceptor Antagonists for the Manufacture of a Medicament for the Treatment of Disorders of the Outer Retina
    Publication number: 20100249134
    Abstract: Compositions and methods for treating disorders of the outer retina with ?-adrenoceptor antagonists are disclosed.
    Type: Application
    Filed: June 9, 2010
    Publication date: September 30, 2010
    Applicant: ALCON, INC.
    Inventors: Robert J. Collier, Jr., Louis DeSantis, JR., Michael A. Kapin
  • Use of ?-adrenoceptor antagonists for the manufacture of a medicament for the treatment of disorders of the outer retina
    Patent number: 7081482
    Abstract: The invention is directed to the use of ?-adrenoceptor antagonists for the manufacture of a medicament for the treatment of disorders of the outer retina.
    Type: Grant
    Filed: November 29, 2000
    Date of Patent: July 25, 2006
    Assignee: Alcon, Inc.
    Inventors: Robert J. Collier, Jr., Louis Desantis, Jr., Michael A. Kapin
  • Use of beta-adrenoceptor antagonists for the manufacture of a medicament for the treatment of disorders of the outer retina
    Publication number: 20020193373
    Abstract: The invention is directed to the use of beta-adrenoceptor antagonists for the manufacture of a medicament for the treatment of disorders of the outer retina.
    Type: Application
    Filed: May 15, 2002
    Publication date: December 19, 2002
    Inventors: Robert J. Collier, Jr., Louis Desantis, Jr., Michael A. Kapin
  • Combination therapy for treating glaucoma
    Patent number: 6441047
    Abstract: Methods for treating persons with glaucoma or ocular hypertension with glutamate antagonists and IOP-lowering compounds are disclosed.
    Type: Grant
    Filed: March 12, 1999
    Date of Patent: August 27, 2002
    Assignee: Alcon Manufacturing Ltd..
    Inventor: Louis DeSantis, Jr.
  • Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension
    Patent number: 6344478
    Abstract: Disclosed is the use of cloprostenol and fluprostenol analogues in combination with carbonic anhydrase inhibitors for the treatment of glaucoma and ocular hypertension and ophthalmic compositions therefor.
    Type: Grant
    Filed: February 6, 2001
    Date of Patent: February 5, 2002
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Thomas R. Dean, Jesse A. May, Verney L. Sallee, Louis Desantis, Jr.
  • Brinzolamide and brimonidine for treating glaucoma
    Patent number: 6316441
    Abstract: Methods and compositions for treating ocular conditions which find their etiology in compromised ocular blood flow with brinzolamide and brimonidine are disclosed.
    Type: Grant
    Filed: April 11, 2001
    Date of Patent: November 13, 2001
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Thomas R. Dean, Louis Desantis, Jr., Billie M. York
  • Use of calpain inhibitors to treat ocular neural pathology
    Patent number: 6303579
    Abstract: The invention provides pharmaceutical compositions containing calpain inhibitors and methods of using these calpain inhibitors to prevent or ameliorate ocular neural tissue disease or damage.
    Type: Grant
    Filed: April 5, 1999
    Date of Patent: October 16, 2001
    Assignee: Alcon Laboratories, Inc.
    Inventors: Iok-Hou Pang, Michael A. Kapin, Louis DeSantis, Jr.
  • Brinzolamide and brimonidine for treating ocular conditions
    Patent number: 6242442
    Abstract: Methods and compositions for treating ocular conditions which find their etiology in compromised ocular blood flow with brinzolamide and brimonidine are disclosed.
    Type: Grant
    Filed: August 4, 2000
    Date of Patent: June 5, 2001
    Assignee: Alcon Laboratories, Inc.
    Inventors: Thomas R. Dean, Louis Desantis, Jr., Billie M. York
  • Treatment of ischemic disorders of the retina and optic nerve head
    Patent number: 6020352
    Abstract: The use of polyamine site antagonists in treating ischemic disorders of the retina and optic nerve head are disclosed. Especially preferred are certain 1-phenyl-2-piperidinoalkanol derivatives, such as eliprodil and ifenprodil.
    Type: Grant
    Filed: November 18, 1997
    Date of Patent: February 1, 2000
    Assignee: Synthelabo
    Inventors: Michael A. Kapin, Louis Desantis, Jr., Bernard Scatton, Salomon Langer
  • Topical anti-glaucoma compositions
    Patent number: 5932572
    Abstract: Ophthalmic pharmaceutical compositions useful in controlling elevated intraocular pressure associated with glaucoma and ocular hypertension are described. The compositions comprise a combination of a beta-blocker and a carbonic anhydrase inhibitor to reduce the production of aqueous humor, preferably formulated as a suspension having a pH between about 6.8 and about 7.8. These compositions may additionally contain a mucomimetic anionic polymer and/or a finely-divided drug carrier substrate to provide sustained release. A method of controlling elevated intraocular pressure with these compositions is also described.
    Type: Grant
    Filed: August 27, 1997
    Date of Patent: August 3, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventors: Thomas R. Dean, Louis Desantis, Jr.
  • Combination therapy for treating glaucoma
    Patent number: 5883108
    Abstract: Methods for treating persons with glaucoma or ocular hypertension with polyamine antagonists and an IOP-lowering compounds are also disclosed.
    Type: Grant
    Filed: August 28, 1997
    Date of Patent: March 16, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventor: Louis DeSantis, Jr.
  • Combinations of prostaglandins and clonidine derivatives for the treatment of glaucoma
    Patent number: 5811443
    Abstract: Combinations of at least one clonidine derivative and at least one prostaglandin are used to treat glaucoma and ocular hypertension without some of the side effects typically associated with topical administration of prostaglandins.
    Type: Grant
    Filed: February 21, 1997
    Date of Patent: September 22, 1998
    Assignee: Alcon Laboratories, Inc.
    Inventors: Louis DeSantis, Jr., Verney L. Sallee
  • Use of certain 9-halo-13,14-dihydroprostaglandins to treat glaucoma and ocular hypertension
    Patent number: 5721273
    Abstract: 9-Halo-13,14-dihydroprostaglandins are useful in the treatment of glaucoma and ocular hypertension. Also disclosed are ophthalmic, pharmaceutical compositions comprising such prostaglandins.
    Type: Grant
    Filed: December 15, 1993
    Date of Patent: February 24, 1998
    Assignee: Alcon Laboratories, Inc.
    Inventors: Verney L. Sallee, Louis DeSantis, Jr., Paul W. Zinke, John E. Bishop
  • Use of polyamine antagonists for the treatment of glaucoma
    Patent number: 5710165
    Abstract: Polyamine antagonists are found to be effective in preventing or reducing visual field loss associated with glaucoma. Especially preferred are certain 1-phenyl-2-piperidinoalkanol derivatives, such as eliprodil and ifenprodil.
    Type: Grant
    Filed: July 6, 1994
    Date of Patent: January 20, 1998
    Assignee: Synthelabo
    Inventors: Michael A. Kapin, Louis Desantis, Jr., Salomon Langer
  • Use of cabergoline and related ergoline derivatives for controlling intraocular pressure
    Patent number: 5705510
    Abstract: The use of certain dopaminergic compounds for controlling elevations of intraocular pressure is disclosed. The compounds are ergoline derivatives. The most preferred compound is cabergoline. The compounds have been found to produce a significant reduction of intraocular pressure.
    Type: Grant
    Filed: October 25, 1995
    Date of Patent: January 6, 1998
    Assignee: Alcon Laboratories, Inc.
    Inventors: Louis DeSantis, Jr., Verney L. Sallee, Marsha A. McLaughlin, Manoj L. Maniar
  • Use of certain 9-haloprostaglandins to treat glaucoma and ocular hypertension
    Patent number: 5627209
    Abstract: 9-Haloprostaglandins are useful in the treatment of glaucoma and ocular hypertension. Also disclosed are ophthalmic, pharmaceutical compositions comprising such prostaglandins.
    Type: Grant
    Filed: October 25, 1995
    Date of Patent: May 6, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Louis DeSantis, Jr., Verney L. Sallee
  • Combinations of prostaglandins and clonidine derivatives for the treatment of glaucoma
    Patent number: 5605922
    Abstract: Combinations of at least one clonidine derivative and at least one prostaglandin are used to treat glaucoma and ocular hypertension without some of the side effects typically associated with topical administration of prostaglandins.
    Type: Grant
    Filed: December 12, 1995
    Date of Patent: February 25, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Louis DeSantis, Jr., Verney L. Sallee
  • Intraocular irrigating solution containing a polyamine antagonist
    Patent number: 5604244
    Abstract: Pharmaceutical compositions useful in ophthalmic surgery are described. The compositions include one or more polyamine antagonists, and are useful for preventing or treating excitotoxicity associated with ophthalmic surgery. Methods of using the compositions in connection with ophthalmic surgical procedures are also described.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: February 18, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Louis DeSantis, Jr., Michael A. Kapin
  • Use of cloprostenol, fluprostenol and their salts and esters to treat glaucoma and ocular hypertension
    Patent number: 5510383
    Abstract: Disclosed is the use of cloprostenol, fluprostenol, and their pharmaceutically acceptable salts and esters for the treatment of glaucoma and ocular hypertension. Also disclosed are ophthalmic compositions comprising said compounds.
    Type: Grant
    Filed: August 3, 1993
    Date of Patent: April 23, 1996
    Assignee: Alcon Laboratories, Inc.
    Inventors: John E. Bishop, Louis DeSantis, Jr., Verney L. Sallee