Patents by Inventor Louis DiDone

Louis DiDone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment or Prevention of Fungal Infections with PDK1 Inhibitors
    Publication number: 20150238495
    Abstract: Provided are methods of treating or preventing a fungal infection in a subject. The methods comprise identifying a subject with or at risk of developing a fungal infection and administering to the subject a therapeutically effective amount of an inhibitor or a fungal phosphoinositide-dependent kinase 1 (PDK-1) or a homolog thereof. Inhibition of the fungal PDK-1 or homolog thereof results in the treatment or prevention of a fungal infection in the subject. Also provided are compositions comprising an inhibitor of a fungal phosphoinositide-dependent kinase 1 (PDK-1) or a homolog thereof, and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: October 24, 2014
    Publication date: August 27, 2015
    Applicant: UNIVERSITY OF ROCHESTER
    Inventors: Damian Krysan, Louis DiDone, Bonnie K. Baxter
  • Treatment or prevention of fungal infections with PDK1 inhibitors
    Patent number: 8889680
    Abstract: Provided are methods of treating or preventing a fungal infection in a subject. The methods comprise identifying a subject with or at risk of developing a fungal infection and administering to the subject a therapeutically effective amount of an inhibitor or a fungal phosphoinositide-dependent kinase 1 (PDK-1) or a homolog thereof. Inhibition of the fungal PDK-1 or homolog thereof results in the treatment or prevention of a fungal infection in the subject. Also provided are compositions comprising an inhibitor of a fungal phosphoinositide-dependent kinase 1 (PDK-1) or a homolog thereof, and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: November 17, 2011
    Date of Patent: November 18, 2014
    Assignee: University of Rochester
    Inventors: Damian Krysan, Louis DiDone, Bonnie K. Baxter
  • Treatment or Prevention of Fungal Infections with PDK1 Inhibitors
    Publication number: 20120122872
    Abstract: Provided are methods of treating or preventing a fungal infection in a subject. The methods comprise identifying a subject with or at risk of developing a fungal infection and administering to the subject a therapeutically effective amount of an inhibitor or a fungal phosphoinositide-dependent kinase 1 (PDK-1) or a homolog thereof. Inhibition of the fungal PDK-1 or homolog thereof results in the treatment or prevention of a fungal infection in the subject. Also provided are compositions comprising an inhibitor of a fungal phosphoinositide-dependent kinase 1 (PDK-1) or a homolog thereof, and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: November 17, 2011
    Publication date: May 17, 2012
    Applicant: UNIVERSITY OF ROCHESTER
    Inventors: Damian Krysan, Louis DiDone, Bonnie K. Baxter