Patents by Inventor Louis E. Begin

Louis E. Begin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aminoalkylsulfides, aminoalkylsulfoxides, and aminoalkylsulfones
    Patent number: 4281118
    Abstract: Novel aminoalkylsulfides, aminoalkylsulfoxides and aminoalkylsulfones of the general formula ##STR1## wherein y and z independently represent the integer 0, 1 or 2; a represents the integer 0 or 2; n represents the integer 1, 2, 3 or 4; R.sub.1 independently represent lower alkyl or hydrogen or alternatively R.sub.1 and R.sub.2 taken together with the adjacent nitrogen atom represent a 5 or 6 membered heterocyclic ring which may optionally contain an oxygen atom whereby a morpholino, piperidino, or pyrrolidino grouping is formed; R.sub.3 represents halo such as chloro or bromo, lower alkylthio, arloweralkylthio, arylthio such as 4-methylphenylthio, 4-morpholinylloweralkylthio such as 4-morpholinylpropylthio, lower alkyl or arloweralkylamino such as 4-methoxybenzenemethanamino; R.sub.4 represents hydrogen or lower alkyl. The invention also includes the pharmaceutically-acceptable salts of the compounds described herein.
    Type: Grant
    Filed: June 18, 1979
    Date of Patent: July 28, 1981
    Assignee: The Dow Chemical Company
    Inventors: Joseph E. Dunbar, Louis E. Begin
  • Aminoalkylthiopurines
    Patent number: 4189579
    Abstract: Novel aminoalkyl purine and pyrazolopyrimidine compounds useful in the inhibition of blood platelet aggregation in animals.
    Type: Grant
    Filed: November 20, 1978
    Date of Patent: February 19, 1980
    Assignee: The Dow Chemical Company
    Inventors: Joseph E. Dunbar, Louis E. Begin
  • Substituted phenylthioalkylamines and compositions thereof
    Patent number: 4183927
    Abstract: Novel substituted phenylthioalkylamines, salts and pharmaceutical compositions thereof wherein the sulfur may appear as a sulfide, sulfinyl or sulfonyl are disclosed as antithrombotic agents.
    Type: Grant
    Filed: September 13, 1977
    Date of Patent: January 15, 1980
    Assignee: The Dow Chemical Company
    Inventors: Louis E. Begin, Robert J. Broersma, Jr., George D. Dickerson, Joseph E. Dunbar
  • Pyrazolopyrimidines
    Patent number: 4169948
    Abstract: Novel aminoalkyl purine and pyrazolopyrimidine compounds useful in the inhibition of blood platelet aggregation in animals.
    Type: Grant
    Filed: November 20, 1978
    Date of Patent: October 2, 1979
    Assignee: The Dow Chemical Company
    Inventors: Joseph E. Dunbar, Louis E. Begin
  • Method for inhibiting ADP-induced platelet aggregation using phenylthioalkylamines
    Patent number: 4155907
    Abstract: A method for inhibiting blood platelet aggregation in a mammal by administering internally to the mammal an effective amount of a phenylthio(sulfinyl or sulfonyl)alkylamine compound or a pharmaceutically-acceptable salt thereof.
    Type: Grant
    Filed: August 16, 1976
    Date of Patent: May 22, 1979
    Assignee: The Dow Chemical Company
    Inventors: Joseph E. Dunbar, Louis E. Begin, Robert J. Broersma, George D. Dickerson
  • Method for inhibiting ADP-induced platelet aggregation using phenylthioalkylamines
    Patent number: 4141983
    Abstract: A method for inhibiting blood platelet aggregation in a mammal by administering internally to the mammal an effective amount of a phenylthio(sulfinyl or sulfonyl)alkylamine compound or a pharmaceutically-acceptable salt thereof.
    Type: Grant
    Filed: September 14, 1977
    Date of Patent: February 27, 1979
    Assignee: The Dow Chemical Company
    Inventors: Joseph E. Dunbar, Louis E. Begin, Robert J. Broesma, George D. Dickerson
  • Pyrazolopyrimidines
    Patent number: 4139705
    Abstract: Novel aminoalkyl purine and pyrazolopyrimidine compounds useful in the inhibition of blood platelet aggregation in animals.
    Type: Grant
    Filed: May 20, 1977
    Date of Patent: February 13, 1979
    Assignee: The Dow Chemical Company
    Inventors: Joseph E. Dunbar, Louis E. Begin
  • Method for inhibiting ADP-induced platelet aggregation using phenylthioalkylamines
    Patent number: 4134996
    Abstract: A method for inhibiting blood platelet aggregation in a mammal by administering internally to the mammal an effective amount of a phenylthio(sulfinyl or sulfonyl)alkylamine compound or a pharmaceutically-acceptable salt thereof.
    Type: Grant
    Filed: September 14, 1977
    Date of Patent: January 16, 1979
    Assignee: The Dow Chemical Company
    Inventors: Joseph E. Dunbar, Louis E. Begin, Robert J. Broersma, George D. Dickerson
  • 3-6 Bis(morpholinoalkylthio)-pyridazines
    Patent number: 4118564
    Abstract: This invention concerns novel aminoalkylthiopyridazine compounds useful for inhibiting the aggregation of blood platelets in animals and a process for preparing the compounds from an isothiuronium salt generated in situ from an aminoalkyl halide and thiourea. The compounds also have fungicidal and nematocidal properties.
    Type: Grant
    Filed: July 22, 1977
    Date of Patent: October 3, 1978
    Assignee: The Dow Chemical Company
    Inventors: Joseph E. Dunbar, Louis E. Begin
  • Morpholinoalkylthiopyridazine compounds
    Patent number: 4087605
    Abstract: This invention concerns novel aminoalkylthiopyridazine compounds useful for inhibiting the aggregation of blood platelets in animals and a process for preparing the compounds from an isothiuronium salt generated in situ from an aminoalkyl halide and thiourea. The compounds also have fungicidal and nematocidal properties.
    Type: Grant
    Filed: July 22, 1977
    Date of Patent: May 2, 1978
    Assignee: The Dow Chemical Company
    Inventors: Joseph E. Dunbar, Louis E. Begin
  • Antithrombotic 1,3,4-thiadiazole
    Patent number: 4074049
    Abstract: A series of 1,3,4-thiadiazoles substituted in the 2,5-position with amino, dialkylaminoalkylthio, or heterocyclicalkylthio are useful as antithrombotic agents.
    Type: Grant
    Filed: November 19, 1976
    Date of Patent: February 14, 1978
    Assignee: The Dow Chemical Company
    Inventors: Louis E. Begin, Joseph E. Dunbar
  • Aminoalkylthiopyridazine compounds
    Patent number: 4058520
    Abstract: This invention concerns novel aminoalkylthiopyridazine compounds useful for inhibiting the aggregation of blood platelets in animals and a process for preparing the compounds from an isothiuronium salt generated in situ from an aminoalkyl halide and thiourea. The compounds also have fungicidal and nematocidal properties.
    Type: Grant
    Filed: May 7, 1976
    Date of Patent: November 15, 1977
    Assignee: The Dow Chemical Company
    Inventors: Joseph E. Dunbar, Louis E. Begin