Patents by Inventor Louis Fries

Louis Fries has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7121924
    Abstract: An attachable abrasive article comprises an abrasive member having an attachment device affixed thereto. The attachment device comprises a fastener having a flange thereon. Thermoplastic material is disposed between the flange and the abrasive article. The disclosure also concerns methods of making and using attachable abrasive articles.
    Type: Grant
    Filed: April 20, 2004
    Date of Patent: October 17, 2006
    Assignee: 3M Innovative Properties Company
    Inventors: Peter Joseph Fritz, Richard Louis Fry
  • Patent number: 5968355
    Abstract: An apparatus is provided having a rotor inside a membrane for the aseptic vortex flow concentration of a liquid or semisolid dispersion which has a shed-resistant bearing interface so that unwanted bearing material does not contaminate the substances, e.g., pharmaceutical and biological materials, that are being processed.
    Type: Grant
    Filed: November 23, 1998
    Date of Patent: October 19, 1999
    Assignee: Matrix Pharmaceutical, Inc.
    Inventors: Richard Lee, Daniel Prows, Louis Fries
  • Patent number: 5925246
    Abstract: An apparatus is provided having a rotor inside a membrane for the aseptic vortex flow concentration of a liquid or semisolid dispersion which has a shed-resistant bearing interface so that unwanted bearing material does not contaminate the substances, e.g., pharmaceutical and biological materials, that are being processed.
    Type: Grant
    Filed: October 31, 1996
    Date of Patent: July 20, 1999
    Assignee: Matrix Pharmaceutical, Inc.
    Inventors: Richard Lee, Daniel Prows, Louis Fries
  • Patent number: 5874006
    Abstract: A process for the aseptic concentration of collagen from about 0.25% (w/w) suspensions to gels of 15% using vortex flow filtration with a variety of membrane types--ultrafiltration and microfiltration and polymeric and stainless steel is provided. The resulting gels are suitable for use in medical products and/or pharmaceutical formulations. This process achieves high degree of concentration in a closed system and at high flux with minimal trans-membrane pressure drop.
    Type: Grant
    Filed: October 31, 1996
    Date of Patent: February 23, 1999
    Assignee: Matrix Pharmaceutical, Inc.
    Inventors: Richard Lee, Daniel Prows, Louis Fries
  • Patent number: 5550188
    Abstract: Pharmaceutically acceptable, non-immunogenic compositions are formed by covalently binding atelopeptide collagen to pharmaceutically pure, synthetic, hydrophilic polymers via specific types of chemical bonds to provide collagen/polymer conjugates. The atelopeptide collagen can be type I, type II or type III and may be fibrillar or non-fibrillar. The synthetic hydrophilic polymer may be polyethylene glycol and derivatives thereof having a weight average molecular weight over a range of from about 100 to about 20,000. The compositions may include other components such as liquid, pharmaceutically acceptable, carriers to form injectable formulations, and/or biologically active proteins such as growth factors. The collagen-polymer conjugates of the invention generally contain large amounts of water when formed. The conjugates can be dehydrated to form a relatively solid object.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: August 27, 1996
    Assignee: Collagen Corporation
    Inventors: Woonza Rhee, Donald G. Wallace, Alan S. Michaels, Ramon A. Burns, Jr., Louis Fries, Frank DeLustro, Hanne Bentz
  • Patent number: 5543441
    Abstract: Collagen, particularly atelopeptide collagen, exhibits improved handling characteristics when chemically conjugated and/or crosslinked with a synthetic hydrophilic polymer.
    Type: Grant
    Filed: April 24, 1995
    Date of Patent: August 6, 1996
    Assignee: Collagen Corporation
    Inventors: Woonza Rhee, Donald G. Wallace, Alan S. Michaels, Ramon A. Burns, Jr., Louis Fries, Frank DeLustro, Hanne Bentz
  • Patent number: 5523348
    Abstract: Collagen, particularly atelopeptide collagen, exhibits improved handling characteristics when chemically conjugated and/or crosslinked with a synthetic hydrophilic polymer.
    Type: Grant
    Filed: August 18, 1994
    Date of Patent: June 4, 1996
    Assignee: Collagen Corporation
    Inventors: Woonza Rhee, Donald G. Wallace, Alan S. Michaels, Ramon A. Burns, Jr., Louis Fries, Frank DeLustro, Hanne Bentz
  • Patent number: 5446091
    Abstract: Pharmaceutically acceptable, non-immunogenic compositions are formed by covalently binding atelopeptide collagen to pharmaceutically pure, synthetic, hydrophilic polymers via specific types of chemical bonds to provide collagen/polymer conjugates. The atelopeptide collagen can be type I, type II or type III and may be fibrillar or non-fibrillar. The synthetic hydrophilic polymer may be polyethylene glycol and derivatives thereof having a weight average molecular weight over a range of from about 100 to about 20,000. The compositions may include other components such as liquid, pharmaceutically acceptable, carriers to form injectable formulations, and/or biologically active proteins such as growth factors. The collagen-polymer conjugates of the invention generally contain large amounts of water when formed. The conjugates can be dehydrated to form a relatively solid object.
    Type: Grant
    Filed: January 5, 1995
    Date of Patent: August 29, 1995
    Assignee: Collagen Corporation
    Inventors: Woonza Rhee, Donald G. Wallace, Alan S. Michaels, Ramon A. Burns, Jr., Louis Fries, Frank DeLustro, Hanne Bentz
  • Patent number: 5413791
    Abstract: Pharmaceutically acceptable, non-immunogenic compositions are formed by covalently binding atelopeptide collagen to pharmaceutically pure, synthetic, hydrophilic polymers via specific types of chemical bonds to provide collagen/polymer conjugates. The atelopeptide collagen can be type I, type II or type III and may be fibrillar or non-fibrillar. The synthetic hydrophilic polymer may be polyethylene glycol and derivatives thereof having a weight average molecular weight over a range of from about 100 to about 20,000. The compositions may include other components such as liquid, pharmaceutically acceptable, carriers to form injectable formulations, and/or biologically active proteins such as growth factors. The collagen-polymer conjugates of the invention generally contain large amounts of water when formed. The conjugates can be dehydrated to form a relatively solid object.
    Type: Grant
    Filed: February 17, 1994
    Date of Patent: May 9, 1995
    Assignee: Collagen Corporation
    Inventors: Woonza Rhee, Donald G. Wallace, Alan S. Michaels, Ramon A. Burns, Jr., Louis Fries, Frank DeLustro, Hanne Bentz
  • Patent number: 5383930
    Abstract: A device for correcting fine superficial facial lines which comprises a syringe fitted with a 31-33 gauge needle and an aqueous suspension of noncrosslinked fibrillar atelopeptide collagen contained within the syringe barrel, the concentration of collagen in the suspension being in the range of 10 to 50 mg/ml and the suspension exhibiting an extrusion plot in which there is a smooth substantially linear increase in force up to a substantially constant force in the range of 5 to 30 newtons.
    Type: Grant
    Filed: November 2, 1992
    Date of Patent: January 24, 1995
    Assignee: Collagen Corporation
    Inventors: Ann Brannan, Roseann Burhenne, Frank A. Delustro, Thomas L. Smestad, Louis Fries, Rees M. Orland
  • Patent number: 5376375
    Abstract: Collagen, particularly atelopeptide collagen, exhibits improved handling characteristics when chemically conjugated and/or crosslinked with a synthetic hydrophilic polymer.
    Type: Grant
    Filed: January 5, 1994
    Date of Patent: December 27, 1994
    Assignee: Collagen Corporation
    Inventors: Woonza Rhee, Donald G. Wallace, Alan S. Michaels, Ramon A. Burns, Jr., Louis Fries, Frank DeLustro, Hanne Bentz
  • Patent number: 5366498
    Abstract: A device for correcting fine superficial facial lines which comprises a syringe fitted with a 31-33 gauge needle and an aqueous suspension of noncrosslinked fibrillar atelopeptide collagen contained within the syringe barrel, the concentration of collagen in the suspension being in the range of 10 to 50 mg/ml and the suspension exhibiting an extrusion plot in which there is a smooth substantially linear increase in force up to a substantially constant force in the range of 5 to 30 newtons.
    Type: Grant
    Filed: February 10, 1993
    Date of Patent: November 22, 1994
    Assignee: Collagen Corporation
    Inventors: Ann Brannan, Roseann Burhenne, Frank A. Delustro, Thomas L. Smestad, Louis Fries, Rees M. Orland
  • Patent number: 5328955
    Abstract: Pharmaceutically acceptable, non-immunogenic compositions are formed by covalently binding atelopeptide collagen to pharmaceutically pure, synthetic, hydrophilic polymers via specific types of chemical bonds to provide collagen/polymer conjugates. The atelopeptide collagen can be type I, type II or type III and may be fibrillar or non-fibrillar. The synthetic hydrophilic polymer may be polyethylene glycol and derivatives thereof having a weight average molecular weight over a range of from about 100 to about 20,000. The compositions may include other components such as liquid, pharmaceutically acceptable, carriers to form injectable formulations, and/or biologically active proteins such as growth factors. The collagen-polymer conjugates of the invention generally contain large amounts of water when formed. The conjugates can be dehydrated to form a relatively solid object.
    Type: Grant
    Filed: July 30, 1992
    Date of Patent: July 12, 1994
    Assignee: Collagen Corporation
    Inventors: Woonza Rhee, Donald G. Wallace, Alan S. Michaels, Ramon A. Burns, Jr., Louis Fries, Frank DeLustro, Hanne Bentz
  • Patent number: 5324775
    Abstract: Pharmaceutically acceptable, non-immunogenic compositions are formed by covalently binding biologically inactive, natural, biocompatible polymer to pharmaceutically pure, synthetic, hydrophilic polymers via specific types of chemical bonds to provide biocompatible conjugates. The synthetic hydrophilic polymer may be polyethylene glycol and derivatives thereof having a weight average molecular weight over a range of from about 100 to about 20,000. The compositions may include other components such as liquid, pharmaceutically acceptable, carriers to form injectable formulations, and/or biologically active proteins such as growth factors. The conjugates of the invention generally contain large amounts of water when formed. The conjugates can be dehydrated to form a relatively solid object. The dehydrated, solid object can be ground into particles which can be suspended in a non-aqueous fluid such as an oil and injected into a living (preferably human) being for the purpose of providing soft tissue augmentation.
    Type: Grant
    Filed: July 2, 1992
    Date of Patent: June 28, 1994
    Assignee: Collagen Corporation
    Inventors: Woonza Rhee, Donald G. Wallace, Alan S. Michaels, Ramon A. Burns, Jr., Louis Fries, Frank DeLustro, Hanne Bentz
  • Patent number: 5308889
    Abstract: Medical articles in the form of strings are formed by covalently binding collagen to pharmaceutically pure, synthetic, hydrophilic polymers via specific types of chemical bonds to provide collagen/polymer conjugate formulations which are extruded to make the strings. The collagen may be recombinantly produced human collagen or collagen extracted from any source, such as a bovine source or human placenta, and purified and can be of various types and may be fibrillar or non-fibrillar. The synthetic hydrophilic polymer may be polyethylene glycol and derivatives thereof having an average molecular weight over a range of from about 100 to about 20,000. The string can be designed to incorporate other components such as fluid, pharmaceutically acceptable carriers to form injectable formulations, and/or biologically active proteins such as growth factors or cytokines. The strings contain large amounts of water when extruded and may then be dehydrated to form relatively solid but flexible strings.
    Type: Grant
    Filed: December 2, 1992
    Date of Patent: May 3, 1994
    Assignee: Collagen Corporation
    Inventors: Woonza Rhee, Louis Fries, Ramesh Damani, Kimberly McCullough, Frank DeLustro
  • Patent number: 5306500
    Abstract: Collagen, particularly atelopeptide collagen, exhibits improved handling characteristics when chemically conjugated and/or crosslinked with a synthetic hydrophilic polymer.
    Type: Grant
    Filed: August 23, 1993
    Date of Patent: April 26, 1994
    Assignee: Collagen Corporation
    Inventors: Woonza Rhee, Donald G. Wallace, Alan S. Michaels, Ramon A. Burns, Jr., Louis Fries, Frank DeLustro, Hanne Bentz
  • Patent number: 5304595
    Abstract: Collagen, particularly atelopeptide collagen, exhibits improved handling characteristics when chemically conjugated and/or crosslinked with a synthetic hydrophilic polymer.
    Type: Grant
    Filed: December 30, 1992
    Date of Patent: April 19, 1994
    Assignee: Collagen Corporation
    Inventors: Woonza Rhee, Donald G. Wallace, Alan S. Michaels, Ramon A. Burns, Jr., Louis Fries, Frank DeLustro, Hanne Bentz
  • Patent number: 5264214
    Abstract: Collagen, particularly atelopeptide collagen, exhibits improved handling characteristics when chemically conjugated and/or crosslinked with a synthetic hydrophilic polymer.
    Type: Grant
    Filed: August 14, 1992
    Date of Patent: November 23, 1993
    Assignee: Collagen Corporation
    Inventors: Woonza Rhee, Donald G. Wallace, Alan S. Michaels, Ramon A. Burns, Jr., Louis Fries, Frank DeLustro, Hanne Bentz
  • Patent number: 5162430
    Abstract: Collagen, particularly atelopeptide collagen, exhibits improved handling characteristics when chemically conjugated and/or crosslinked with a synthetic hydrophilic polymer.
    Type: Grant
    Filed: November 14, 1989
    Date of Patent: November 10, 1992
    Assignee: Collagen Corporation
    Inventors: Woonza Rhee, Donald G. Wallace, Alan S. Michaels, Ramon A. Burns, Jr., Louis Fries, Frank DeLustro, Hanne Bentz