Abstract: A health risk assessment device includes a mouthpiece, a flow path in fluid communication with the mouthpiece, a sensor disposed in the flow path and configured to generate a representation of a spirometric parameter of air flow in the flow path exhaled by a user through the mouthpiece, a user interface configured to allow the user to provide user profile data including smoking history data, and a processor coupled to the sensor and the user interface and configured to determine an output indicative of a risk that the user develops a respiratory, cardiopulmonary, or cardiovascular disease based on the spirometric parameter representation and the smoking history data.