Patents by Inventor Louis M. Messina

Louis M. Messina has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating a wound using epigenetic regulation
    Patent number: 11814623
    Abstract: Methods of treating wounds in a subject using one or both of a DNA methyltransferase 1 (DNMT1) inhibitor or a nicotinamide adenine dinucleotide phosphate oxidase 2 (NOX2) inhibitor, and compositions for use in these methods.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: November 14, 2023
    Assignee: University of Massachusetts
    Inventor: Louis M. Messina
  • Targeting microRNA-101-3p in cancer therapy
    Patent number: 11459568
    Abstract: Methods and compositions for treating cancer, e.g., colorectal cancer, using a miR-101-3p inhibitor.
    Type: Grant
    Filed: October 31, 2017
    Date of Patent: October 4, 2022
    Assignee: University of Massachusetts
    Inventors: Louis M. Messina, Guodong Tie
  • TARGETING MICRORNA-101-3P IN CANCER THERAPY
    Publication number: 20210277402
    Abstract: Methods and compositions for treating cancer, e.g., colorectal cancer, using a miR-101-3p inhibitor.
    Type: Application
    Filed: October 31, 2017
    Publication date: September 9, 2021
    Inventors: Louis M. Messina, Guodong Tie
  • Methods and compositions to reduce oxidative stress
    Patent number: 11090305
    Abstract: The invention relates to therapeutic applications for compositions that reduce the level of oxidative stress on cells in vivo or in vitro. The invention describes methods for improving the therapeutic properties of stem cells. The invention also provides combination therapies that are useful to balance the oxidative microenvironment of cells in vivo or in vitro.
    Type: Grant
    Filed: April 3, 2019
    Date of Patent: August 17, 2021
    Assignee: University of Massachusetts
    Inventor: Louis M. Messina
  • Cancer Immunotherapy
    Publication number: 20200316123
    Abstract: Methods of providing populations of NKT and/or ?? T cells, and their use, e.g., in therapies such as cancer immunotherapy.
    Type: Application
    Filed: March 4, 2020
    Publication date: October 8, 2020
    Inventors: Louis M. Messina, Guodong Tie
  • Cancer immunotherapy
    Patent number: 10632151
    Abstract: Methods of providing populations of NKT and/or ?? T cells, and their use, e.g., in therapies such as cancer immunotherapy.
    Type: Grant
    Filed: January 22, 2016
    Date of Patent: April 28, 2020
    Assignee: University of Massachusetts
    Inventors: Louis M. Messina, Guodong Tie
  • Methods And Compositions To Reduce Oxidative Stress
    Publication number: 20190275047
    Abstract: The invention relates to therapeutic applications for compositions that reduce the level of oxidative stress on cells in vivo or in vitro. The invention describes methods for improving the therapeutic properties of stem cells. The invention also provides combination therapies that are useful to balance the oxidative microenvironment of cells in vivo or in vitro.
    Type: Application
    Filed: April 3, 2019
    Publication date: September 12, 2019
    Inventor: Louis M. Messina
  • Methods of Treating a Wound Using Epigenetic Regulation
    Publication number: 20190233828
    Abstract: Methods of treating wounds in a subject using one or both of a DNA methyltransferase 1 (DNMT1) inhibitor or a nicotinamide adenine dinucleotide phosphate oxidase 2 (NOX2) inhibitor, and compositions for use in these methods.
    Type: Application
    Filed: December 21, 2018
    Publication date: August 1, 2019
    Inventor: Louis M. Messina
  • Methods and compositions to reduce oxidative stress
    Patent number: 10251887
    Abstract: The invention relates to therapeutic applications for compositions that reduce the level of oxidative stress on cells in vivo or in vitro. The invention describes methods for improving the therapeutic properties of stem cells. The invention also provides combination therapies that are useful to balance the oxidative microenvironment of cells in vivo or in vitro.
    Type: Grant
    Filed: February 21, 2017
    Date of Patent: April 9, 2019
    Assignee: University of Massachusetts
    Inventor: Louis M. Messina
  • Cancer immunotherapy
    Patent number: 10034901
    Abstract: Methods of providing populations of NKT and/or ?? T cells, and their use, e.g., in therapies such as cancer immunotherapy.
    Type: Grant
    Filed: January 22, 2016
    Date of Patent: July 31, 2018
    Assignee: University of Massachusetts
    Inventors: Louis M. Messina, Guodong Tie
  • Cancer Immunotherapy
    Publication number: 20170368099
    Abstract: Methods of providing populations of NKT and/or ?? T cells, and their use, e.g., in therapies such as cancer immunotherapy.
    Type: Application
    Filed: January 22, 2016
    Publication date: December 28, 2017
    Inventors: Louis M. Messina, Guodong Tie
  • Methods And Compositions To Reduce Oxidative Stress
    Publication number: 20170258796
    Abstract: The invention relates to therapeutic applications for compositions that reduce the level of oxidative stress on cells in vivo or in vitro. The invention describes methods for improving the therapeutic properties of stem cells. The invention also provides combination therapies that are useful to balance the oxidative microenvironment of cells in vivo or in vitro.
    Type: Application
    Filed: February 21, 2017
    Publication date: September 14, 2017
    Inventor: Louis M. Messina
  • Methods and compositions to reduce oxidative stress
    Patent number: 9579321
    Abstract: The invention relates to therapeutic applications for compositions that reduce the level of oxidative stress on cells in vivo or in vitro. The invention describes methods for improving the therapeutic properties of stem cells. The invention also provides combination therapies that are useful to balance the oxidative microenvironment of cells in vivo or in vitro.
    Type: Grant
    Filed: November 7, 2014
    Date of Patent: February 28, 2017
    Assignee: University of Massachusetts
    Inventor: Louis M. Messina
  • Cancer Immunotherapy
    Publication number: 20160213715
    Abstract: Methods of providing populations of NKT and/or ?? T cells, and their use, e.g., in therapies such as cancer immunotherapy.
    Type: Application
    Filed: January 22, 2016
    Publication date: July 28, 2016
    Inventors: Louis M. Messina, Guodong Tie
  • Methods and compositions to reduce oxidative stress
    Patent number: 9089573
    Abstract: The invention relates to therapeutic applications for compositions that reduce the level of oxidative stress on cells in vivo or in vitro. The invention describes methods for improving the therapeutic properties of stem cells. The invention also provides combination therapies that are useful to balance the oxidative microenvironment of cells in vivo or in vitro.
    Type: Grant
    Filed: July 22, 2010
    Date of Patent: July 28, 2015
    Assignee: University of Massachusetts
    Inventor: Louis M. Messina
  • Methods And Compositions To Reduce Oxidative Stress
    Publication number: 20150065514
    Abstract: The invention relates to therapeutic applications for compositions that reduce the level of oxidative stress on cells in vivo or in vitro. The invention describes methods for improving the therapeutic properties of stem cells. The invention also provides combination therapies that are useful to balance the oxidative microenvironment of cells in vivo or in vitro.
    Type: Application
    Filed: November 7, 2014
    Publication date: March 5, 2015
    Inventor: Louis M. Messina
  • METHODS AND COMPOSITIONS TO REDUCE OXIDATIVE STRESS
    Publication number: 20120190731
    Abstract: The invention relates to therapeutic applications for compositions that reduce the level of oxidative stress on cells in vivo or in vitro. The invention describes methods for improving the therapeutic properties of stem cells. The invention also provides combination therapies that are useful to balance the oxidative microenvironment of cells in vivo or in vitro.
    Type: Application
    Filed: July 22, 2010
    Publication date: July 26, 2012
    Applicant: University of Massachusetts
    Inventor: Louis M. Messina