Abstract: Methods for treating cancer patients with human platelet derived growth factor receptor alpha inhibiting compounds, in which the patient is identified as having a cancer that is human platelet derived growth factor receptor beta negative.

Abstract: In a multi-station reaction apparatus (1) comprising an annular heat transfer block (30) formed with a plurality of cavities (31) for receiving respective reaction vessels (36), the upper surface of the heat transfer block (30) has a central recess (32) around which the said plurality of cavities (31) are arrayed. The apparatus further comprises a removable cooling module (4), the central recess (32) of the heat transfer block (30) being shaped so as to accommodate the removable cooling module (4) and corresponding surfaces of the central recess (32) of the heat transfer block (30) and the cooling module (4) being shaped such that there is a stepped interface between them. The cooling module (4) comprises a metal block having channels therein through which coolant circulates when the cooling module (4) is in use.

Abstract: There is disclosed a process and apparatus for recovering ethane and heavier hydrocarbons from natural gas by heating the natural gas stream prior to the expansion and introduction thereof into a demethanizer operating under cryogenic conditions. Ethane and the heavier hydrocarbons are recovered from the demethanizer as well as a residual gaseous methane stream which is compressed to a pipeline receiving pressure by the work of expansion without requiring a booster compressor.