Patents by Inventor Louis Michel Marie Mouterde

Louis Michel Marie Mouterde has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Materials and methods for alkene reduction of levoglucosenone by an alkene reductase
    Patent number: 11021724
    Abstract: The subject invention concerns materials and methods for alkene reduction of compounds, such as levoglucosenone (LGO) and (S)-?-hydroxymethyl-?,?-butenolide (HBO), using an alkene reductase enzyme. In one embodiment, a method of the invention comprises alkene reduction of a target compound by reacting the compound with an Old Yellow Enzyme (OYE) that reduces alkene bonds. In one embodiment, the OYE is OYE 2.6 from Pichia stipites and comprises the amino acid sequence of SEQ ID NO: I. In a specific embodiment, the enzyme is an Old Yellow Enzyme (OYE) 2.6 mutant having an amino acid substitution at position 78 in the sequence, wherein the tyrosine at position 78 is substituted with a tryptophan amino acid (Y78W) and is designated as OYE 2.6 Y78W (SEQ ID NO:2).
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: June 1, 2021
    Assignees: University of Florida Research Foundation, Inc., AfroParisTech
    Inventors: Jon Dale Stewart, Florent Allais, Louis Michel Marie Mouterde
  • MATERIALS AND METHODS FOR ALKENE REDUCTION OF LEVOGLUCOSENONE BY AN ALKENE REDUCTASE
    Publication number: 20200010865
    Abstract: The subject invention concerns materials and methods for alkene reduction of compounds, such as levoglucosenone (LGO) and (,S)-Y-hydroxymethyl-a,P-butenolide (HBO), using an alkene reductase enzyme. In one embodiment, a method of the invention comprises alkene reduction of a target compound by reacting the compound with an Old Yellow Enzyme (OYE) that reduces alkene bonds. In one embodiment, the OYE is OYE 2.6 from Pichia stipites and comprises the amino acid sequence of SEQ ID NO: 1. In a specific embodiment, the enzyme is an Old Yellow Enzyme (OYE) 2.6 mutant having an amino acid substitution at position 78 in the sequence, wherein the tyrosine at position 78 is substituted with a tryptophan amino acid (Y78W) and is designated as OYE 2.6 Y78W (SEQ ID NO:2).
    Type: Application
    Filed: March 29, 2018
    Publication date: January 9, 2020
    Inventors: Jon Dale Stewart, Allais Florent, Louis Michel Marie Mouterde