Patents by Inventor Louis N. Jungheim

Louis N. Jungheim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds, methods and formulations for the oral delivery of a glucagon-like peptide (GLP-1) compound or a melanocortin-4 receptor (MC4) agonist peptide
    Patent number: 8765796
    Abstract: The present invention relates to novel compounds, methods, and formulations useful for the oral delivery of a GLP-1 compound or an MC4 agonist peptide.
    Type: Grant
    Filed: August 20, 2013
    Date of Patent: July 1, 2014
    Assignee: Emisphere Technologies, Inc.
    Inventors: Robert J. Herr, Louis N. Jungheim, John M. McGill, Kenneth J. Thrasher, Muralikrishna Valluri
  • Ring modified cyclic peptide analogs
    Publication number: 20040068094
    Abstract: A method for modifying the cyclic peptide ring system of Echinocandin-type compounds to produce new analogs having antifungal activity is provided. The inventive process comprises opening the cyclic peptide ring, cleaving the terminal ornithine unit, inserting at least one new amino acid or other synthetic unit and closing the ring to produce a new cyclic peptide ring structure. The process allows one to incorporate features such as water-solubility into the cyclic peptide ring nucleus, sites for further modification, increase or decrease the number of amino acid or peptide units within the ring nucleus, and increase or decrease the total number of members within the ring. The invention further provides novel Echinocandin type compounds and their use as antifungal or anti-parasitic agents.
    Type: Application
    Filed: September 30, 2003
    Publication date: April 8, 2004
    Inventors: Peter S. Borromeo, Jeffrey D. Cohen, George S. Gregory, Stacy K. Henle, Stephen A. Hitchcock, Louis N. Jungheim, Daniel R. Mayhugh, Timothy A. Shephered, William W. Turner
  • Inhibitors of HIV protease useful for the treatment of AIDS
    Patent number: 5905077
    Abstract: The present invention provides novel HIV protease inhibitors, pharmaceutical formulations containing those compounds and methods of treating and/or preventing HIV infection and/or AIDS.
    Type: Grant
    Filed: November 19, 1997
    Date of Patent: May 18, 1999
    Assignee: Eli Lilly and Company
    Inventors: Louis N. Jungheim, Timothy A. Shepherd
  • Inhibitors of HIV Protease useful for the treatment of Aids
    Patent number: 5733906
    Abstract: The present invention provides novel HIV protease inhibitors, pharmaceutical formulations containing those compounds and methods of treating and/or preventing HIV infection and/or AIDS.
    Type: Grant
    Filed: October 12, 1993
    Date of Patent: March 31, 1998
    Assignee: Eli Lilly and Company
    Inventors: Louis N. Jungheim, Timothy A. Shepherd
  • Inhibitors of HIV protease useful for the treatment of AIDS
    Patent number: 5554653
    Abstract: The present invention provides novel HIV protease inhibitors, pharmaceutical formulations containing those compounds and methods of treating and/or preventing HIV infection and/or AIDS.
    Type: Grant
    Filed: December 22, 1992
    Date of Patent: September 10, 1996
    Assignee: Eli Lilly and Company
    Inventors: Kwan Hui, Charles D. Jones, Louis N. Jungheim, Timothy A. Shepherd
  • Peptidyl substituted benzamides and naphthamies
    Patent number: 5502061
    Abstract: The present invention provides HIV protease inhibitors, pharmaceutical formulations containing those compounds and methods of treating and/or preventing HIV infection and/or AIDS.
    Type: Grant
    Filed: September 26, 1994
    Date of Patent: March 26, 1996
    Assignee: Eli Lilly and Company
    Inventors: Kwan Y. Hui, Charles D. Jones, Louis N. Jungheim, Pamela A. Pennington
  • Intermediate and process for making
    Patent number: 5461154
    Abstract: The present invention provides novel HIV protease inhibitors, pharmaceutical formulations containing those compounds and methods of treating and/or preventing HIV infection and/or AIDS.
    Type: Grant
    Filed: February 2, 1994
    Date of Patent: October 24, 1995
    Assignee: Eli Lilly and Company
    Inventors: Louis N. Jungheim, Timothy A. Shepherd
  • 7-substituted bicyclic pyrazolidinones
    Patent number: 5011938
    Abstract: 7-Substituted bicyclic pyrazolidinone compounds as antimicrobials and the corresponding intermediates, are discussed or provided. The use of the antimicrobial compounds in pharmaceutical compositions and in methods for treating bacterial infections is set forth.
    Type: Grant
    Filed: April 3, 1990
    Date of Patent: April 30, 1991
    Assignee: Eli Lilly and Company
    Inventors: Charles J. Barnett, Richard E. Holmes, Louis N. Jungheim, Sandra K. Sigmund, Robert J. Ternansky
  • 7-substituted bicyclic pyrazolidinones, pharmaceutical compositions and use
    Patent number: 4940718
    Abstract: 7-Substituted bicyclic pyrazolidinone compounds as antimicrobials and the corresponding intermediates, are discussed or provided. The use of the antimicrobial compounds in pharmaceutical compositions and in methods for treating bacterial infections is set forth.
    Type: Grant
    Filed: October 2, 1989
    Date of Patent: July 10, 1990
    Assignee: Eli Lilly and Company
    Inventors: Charles J. Barnett, Richard E. Holmes, Louis N. Jungheim, Sandra K. Sigmund, Robert J. Ternansky
  • Bicyclic pyrazolidinones, compositions and use
    Patent number: 4902707
    Abstract: Bicyclic pyrazolidinones which have antimicrobial and/or herbicidal properties are discussed. The use of these compounds in pharmaceutical compositions, herbicidal compositions, and methods for treating bacterial infections and controlling undesired plants is set forth.
    Type: Grant
    Filed: April 30, 1985
    Date of Patent: February 20, 1990
    Assignee: Eli Lilly and Company
    Inventors: Louis N. Jungheim, Sandra K. Sigmund
  • 2,3-(Dihydro) bicyclic pyrazolidinones
    Patent number: 4826992
    Abstract: 2,3-(Dihydro) bicyclic pyrazolidinones are intermediates for bicyclic pyrazolidinone antimicrobials.
    Type: Grant
    Filed: November 24, 1986
    Date of Patent: May 2, 1989
    Assignee: Eli Lilly and Company
    Inventors: Louis N. Jungheim, Sandra K. Sigmund
  • Substituted diazolidinones
    Patent number: 4826993
    Abstract: 4-Substituted 1-(optionally substituted)diazolidinones are intermediates to 7-substituted bicyclic pyrazolidinone antimicrobials.
    Type: Grant
    Filed: May 14, 1986
    Date of Patent: May 2, 1989
    Assignee: Eli Lilly and Company
    Inventors: Richard E. Holmes, Louis N. Jungheim
  • Pyrazolidinium ylides
    Patent number: 4767871
    Abstract: 4-(Protected amino)-3-oxo-1-(substituted and unsubstituted methylene)-1,2-pyrazolidinium ylides are intermediates to 7-substituted bicyclic pyrazolidione antimicrobials.
    Type: Grant
    Filed: April 30, 1987
    Date of Patent: August 30, 1988
    Assignee: Eli Lilly and Company
    Inventors: Richard E. Holmes, Louis N. Jungheim