Patents by Inventor Louis Plamondon

Louis Plamondon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT OF INFARCTS
    Publication number: 20010002391
    Abstract: This invention is directed to treating ischemia by administering proteasome inhibitors, ubiquitin pathway inhibitors, agents that interfere with the activation of NF-&kgr;B via the ubiquitin proteasome pathway, or mixtures thereof.
    Type: Application
    Filed: February 17, 1998
    Publication date: May 31, 2001
    Inventors: STEPHEN BRAND, ALFRED L. GOLDBERG, LOUIS PLAMONDON, FRANCOIS SOUCY, PETER J. ELLIOTT
  • Synthesis of clasto-lactacystin beta-lactone and analogs thereof
    Patent number: 6133308
    Abstract: The present invention is directed to an improved synthesis of clasto-lactacystin-.beta.-lactone, and analogs thereof, that proceeds in fewer steps and in much greater overall yield than syntheses described in the prior art. The synthetic pathway relies upon a novel stereospecific synthesis of an oxazoline intermediate and a unique stereoselective addition of a formyl amide to the oxazoline. Also described are novel clasto-lactacystin-.beta.-lactones, and analogs thereof and their use as proteosome inhibitors.
    Type: Grant
    Filed: August 14, 1998
    Date of Patent: October 17, 2000
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Fran.cedilla.ois Soucy, Louis Plamondon, Mark Behnke, William Roush
  • Boronic ester and acid compounds, synthesis and uses
    Patent number: 6083903
    Abstract: Disclosed herein are boronic ester and acid compounds, their synthesis and uses. More specifically, disclosed herein is a method for reducing the rate of degradation of proteins in an animal comprising contacting cells of the animal with certain boronic ester and acid compounds.
    Type: Grant
    Filed: May 16, 1995
    Date of Patent: July 4, 2000
    Assignee: LeukoSite, Inc.
    Inventors: Julian Adams, Yu-Ting Ma, Ross Stein, Matthew Baevsky, Louis Grenier, Louis Plamondon
  • Boronic ester and acid compounds, synthesis and uses
    Patent number: 6066730
    Abstract: Disclosed herein is a method for reducing the rate of degradation of proteins in an animal comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and uses.
    Type: Grant
    Filed: May 26, 1998
    Date of Patent: May 23, 2000
    Assignee: ProScript, Inc.
    Inventors: Julian Adams, Yu-Ting Ma, Ross Stein, Matthew Baevsky, Louis Grenier, Louis Plamondon
  • Boronic ester and acid compounds
    Patent number: 5780454
    Abstract: Disclosed herein is a method for reducing the rate of degradation of proteins in an animal comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and uses.
    Type: Grant
    Filed: October 27, 1995
    Date of Patent: July 14, 1998
    Assignee: ProScript, Inc.
    Inventors: Julian Adams, Yu-Ting Ma, Ross Stein, Matthew Baevsky, Louis Grenier, Louis Plamondon