Patents by Inventor Louis S. Kucera

Louis S. Kucera has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lipid analogs for treating viral infections
    Patent number: 5962437
    Abstract: A method of treating viral infections, and in particular HIV-1, hepatitis B virus and herpes viruses, is disclosed. The method comprising administering to a subject in need of such treatment an infection-combating amount of a phospholipid or phospholipid derivative.
    Type: Grant
    Filed: May 2, 1997
    Date of Patent: October 5, 1999
    Assignee: Wake Forest University
    Inventors: Louis S. Kucera, Susan L. Morris-Natschke, Khalid S. Ishaq
  • Triciribine and analogs as antiviral drugs
    Patent number: 5827833
    Abstract: Triciribine and analogs are effective antiviral agents.
    Type: Grant
    Filed: December 19, 1996
    Date of Patent: October 27, 1998
    Assignees: Regents of the University of Michigan, Wake Forest University
    Inventors: Leroy B. Townsend, John C. Drach, Louis S. Kucera
  • Method of treating hepatitis virus infections
    Patent number: 5770584
    Abstract: A method of treating hepatitis virus infection is disclosed. The method comprising administering to a human subject in need of such treatment an effective hepatitis virus-combatting amount of an alkyl lipid or alkyl lipid derivative.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: June 23, 1998
    Assignees: Wake Forest University, University of North Carolina
    Inventors: Louis S. Kucera, Susan L. Morris-Natschke
  • Triciribine and analogs as antiviral drugs
    Patent number: 5633235
    Abstract: Triciribine and analogs are effective antiviral agents.
    Type: Grant
    Filed: July 5, 1994
    Date of Patent: May 27, 1997
    Assignees: Regents of the University of Michigan, Wake Forest University
    Inventors: Leroy B. Townsend, John C. Drach, Louis S. Kucera
  • Quaternary amine containing ether or ester lipid derivatives and therapeutic compositions
    Patent number: 5614548
    Abstract: Quaternary amine-containing ether lipid analogs of the formulaR.sub.1 --X--R.sub.2 --N.sup.+ (R.sub.3) (R.sub.4) (R.sub.5) Z.sup.-are disclosed. R.sub.1 represents a hydrophobic group and R.sub.2 represents the backbone of the molecule, with the quaternary amine being linked directly to the backbone. Pharmaceutical compositions including these compounds and methods of combating tumors with these compounds are disclosed. Also disclosed is a method of combating viral infections with both these compounds and ET-18-OMe and its analogs.
    Type: Grant
    Filed: September 8, 1994
    Date of Patent: March 25, 1997
    Assignee: Wake Forest University
    Inventors: Claude Piantadosi, Khalid S. Ishaq, Canio J. Marasco, Jr., Larry W. Daniel, Louis S. Kucera, Edward J. Modest, Barry P. Goz
  • Ether lipid-nucleoside covalent conjugates
    Patent number: 5512671
    Abstract: Ether lipid nucleoli covalent conjugates and derivatives thereof are disclosed, along with pharmaceutical compositions containing the same and methods of using the same to combat HIV-1 infections. Illustrative are 3'-Azido-3'-deoxythmidine-5'-monophosphate-D,L-3-octadecanamido-2-ethoxypr opane and 3'-Azido-3'-deoxythymidine-5'-butyrate-.gamma.-N,N,N-trimethyl -ammonium-.beta.-(1-phospho-2-ethoxy-3-hexadecyloxypropane).
    Type: Grant
    Filed: April 7, 1995
    Date of Patent: April 30, 1996
    Assignees: Wake Forest University, University of North Carolina at Chapel Hill
    Inventors: Claude Piantadosi, Canio J. Marasco, Jr., Louis S. Kucera