Patents by Inventor Louis Shuster

Louis Shuster has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8071786
    Abstract: Novel indole compounds are disclosed. Also disclosed are methods for using the compounds to treat human and animal disease, pharmaceutical compositions of the compounds, and kits including the compounds.
    Type: Grant
    Filed: December 14, 2009
    Date of Patent: December 6, 2011
    Assignee: Galenea Corp.
    Inventors: Howard P. Sard, Louis Shuster, Bryan Roth, Cynthia Morency, Govindaraj Kumaran, Liang Xu
  • Publication number: 20100137616
    Abstract: Novel indole compounds are disclosed. Also disclosed are methods for using the compounds to treat human and animal disease, pharmaceutical compositions of the compounds, and kits including the compounds.
    Type: Application
    Filed: December 14, 2009
    Publication date: June 3, 2010
    Inventors: Howard P. Sard, Louis Shuster, Bryan Roth, Cynthia Morency, Govindaraj Kumaran, Liang Xu
  • Patent number: 7655691
    Abstract: Novel indole compounds are disclosed. Also disclosed are methods for using the compounds to treat human and animal disease, pharmaceutical compositions of the compounds, and kits including the compounds.
    Type: Grant
    Filed: September 27, 2005
    Date of Patent: February 2, 2010
    Inventors: Howard P. Sard, Louis Shuster, Bryan Roth, Cynthia Morency, Govindaraj Kumaran, Liang Xu
  • Publication number: 20090318527
    Abstract: Novel indole compounds are disclosed. Also disclosed are methods for using the compounds to treat human and animal disease, pharmaceutical compositions of the compounds, and kits including the compounds.
    Type: Application
    Filed: February 11, 2009
    Publication date: December 24, 2009
    Inventors: Howard Sard, Yiliang Zhang, Jie Li, Louis Shuster, Bryan Roth, Niels Jensen
  • Publication number: 20070197651
    Abstract: NMDA receptor antagonists can be used in methods of treatment, for reducing the frequency of stereotypic behaviors in animals and for reducing the frequency of analogous compulsive behaviors in humans, for example, those that have been said to be a manifestation of, or related to, obsessive-compulsive disorder. Of particular interest is the non-competitive NMDA receptor antagonist memantine.
    Type: Application
    Filed: January 17, 2007
    Publication date: August 23, 2007
    Inventors: Louis Shuster, Nicholas Dodman
  • Publication number: 20060167114
    Abstract: NMDA receptor antagonists can be used in methods of treatment, for reducing the frequency of stereotypic behaviors in animals and for reducing the frequency of analogous compulsive behaviors in humans, for example, those that have been said to be a manifestation of, or related to, obsessive-compulsive disorder. Of particular interest is the non-competitive NMDA receptor antagonist memantine.
    Type: Application
    Filed: November 30, 2005
    Publication date: July 27, 2006
    Inventors: Louis Shuster, Nicholas Dodman
  • Publication number: 20060100266
    Abstract: Novel indole compounds are disclosed. Also disclosed are methods for using the compounds to treat human and animal disease, pharmaceutical compositions of the compounds, and kits including the compounds.
    Type: Application
    Filed: September 27, 2005
    Publication date: May 11, 2006
    Applicant: Organix, Inc.
    Inventors: Howard Sard, Louis Shuster, Bryan Roth, Cynthia Morency, Govindaraj Kumaran, Liang Xu
  • Publication number: 20030114474
    Abstract: NMDA receptor antagonists can be used in methods of treatment, for reducing the frequency of stereotypic behaviors in animals and for reducing the frequency of analogous compulsive behaviors in humans, for example, those that have been said to be a manifestation of, or related to, obsessive-compulsive disorder. Of particular interest are the (+) enantiomers of opioid receptor binding compounds, which can reduce the frequency of the behaviors, while having no effects from binding at the opioid receptor.
    Type: Application
    Filed: October 10, 2002
    Publication date: June 19, 2003
    Applicant: The Trustees of Tufts College
    Inventors: Louis Shuster, Nicholas H. Dodman
  • Patent number: 6500838
    Abstract: NMDA receptor antagonists can be used in methods of treatment, for reducing the frequency of stereotypic behaviors in animals and for reducing the frequency of analogous compulsive behaviors in humans, for example, those that have been said to be a manifestation of, or related to, obsessive-compulsive disorder. Of particular interest are the (+) enantiomers of opioid receptor binding compounds, which can reduce the frequency of the behaviors, while having no effects from binding at the opioid receptor.
    Type: Grant
    Filed: February 5, 2001
    Date of Patent: December 31, 2002
    Assignee: The Trustees of Tufts College
    Inventors: Louis Shuster, Nicholas H. Dodman
  • Publication number: 20010011095
    Abstract: NMDA receptor antagonists can be used in methods of treatment, for reducing the frequency of stereotypic behaviors in animals and for reducing the frequency of analogous compulsive behaviors in humans, for example, those that have been said to be a manifestation of, or related to, obsessive-compulsive disorder. Of particular interest are the (+) enantiomers of opioid receptor binding compounds, which can reduce the frequency of the behaviors, while having no effects from binding at the opioid receptor.
    Type: Application
    Filed: February 5, 2001
    Publication date: August 2, 2001
    Applicant: The Trustees of Tufts College Ballou Hall
    Inventors: Louis Shuster, Nicholas H. Dodman
  • Patent number: 6242456
    Abstract: NMDA receptor antagonists can be used in methods of treatment, for reducing the frequency of stereotypic behaviors in animals and for reducing the frequency of analogous compulsive behaviors in humans, for example, those that have been said to be a manifestation of, or related to, obsessive-compulsive disorder. Of particular interest are the (+) enantiomers of opioid receptor binding compounds, which can reduce the frequency of the behaviors, while having no effects from binding at the opioid receptor.
    Type: Grant
    Filed: March 4, 1999
    Date of Patent: June 5, 2001
    Assignee: Trustees of Tufts College
    Inventors: Louis Shuster, Nicholas H. Dodman
  • Patent number: 5314888
    Abstract: The present invention provides a veterinary treatment method for animals suffering from a high arousal state. The treatment employs a class of pharmacologically active compounds having a pyrimidinyl-piperazine ring structure of which the most preferred member is buspirone. These compounds are administered to a variety of different domestic animals and household pets exhibiting behavioral problems which often are refractory to other modes of treatment.
    Type: Grant
    Filed: April 23, 1993
    Date of Patent: May 24, 1994
    Assignee: Trustees of Tufts College
    Inventors: Nicholas H. Dodman, Louis Shuster
  • Patent number: 4692451
    Abstract: A method of treating animals exhibiting stereotypic behavior by administering a therapeutically effective amount of a narcotic antagonist is disclosed. The stereotypic behaviors include cribbing, wind-sucking, head bobbing, head skaking, head nodding, pacing, pawing and stall-walking. A kit for treating this stereotypic behavior is also disclosed.
    Type: Grant
    Filed: December 11, 1985
    Date of Patent: September 8, 1987
    Assignee: Trustees of Tufts College
    Inventors: Nicholas H. Dodman, Louis Shuster