Patents by Inventor Louis Simchowitz

Louis Simchowitz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5750354
    Abstract: A lipoxin transport system which mediates uptake of lipoxin by cells is disclosed. Lipoxin transport into cells by the lipoxin transport system is inhibitable by 3,5-diiodosalicylic acid (DISA), pentachlorophenol (PCP), .alpha.-cyano-.beta.-(1-phenylindol-3-yl)acrylic acid (UK-5099), mersalyl and p-hydroxymercuribenzoate (pHMB). The invention provides methods for identifying inducers, enhancers and inhibitors of the lipoxin transport system. The invention further provides methods for inducing, enhancing or inhibiting lipoxin transport by the lipoxin transport system. Methods for identifying molecules which are transported by the lipoxin transport system, including lipoxin analogs, are also disclosed. Modulation of physiological responses by modulation of lipoxin transport into cells by the lipoxin transport system of the invention are also contemplated.
    Type: Grant
    Filed: March 11, 1994
    Date of Patent: May 12, 1998
    Assignee: Brigham and Women's Hospital
    Inventors: Louis Simchowitz, Charles N. Serhan