Patents by Inventor Louis V. Kirchhoff

Louis V. Kirchhoff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant polypeptides for diagnosing infection with
    Patent number: 8071720
    Abstract: Recombinant polypeptides are disclosed that are useful for diagnosing American trypanosomiasis, or Chagas disease, a disease caused by the infectious agent Trypanosoma cruzi. Preferably, DNA sequences encoding the recombinant proteins are placed in plasmid vectors to be expressed in an organism.
    Type: Grant
    Filed: February 7, 2011
    Date of Patent: December 6, 2011
    Inventors: Louis V Kirchhoff, Keiko Otsu
  • RECOMBINANT POLYPEPTIDES FOR DIAGNOSING INFECTION WITH TRYPANOSOMA CRUZI
    Publication number: 20110171751
    Abstract: Recombinant polypeptides are disclosed that are useful for diagnosing American trypanosomiasis, or Chagas disease, a disease caused by the infectious agent Trypanosoma cruzi. Preferably, DNA sequences encoding the recombinant proteins are placed in plasmid vectors to be expressed in an organism.
    Type: Application
    Filed: February 7, 2011
    Publication date: July 14, 2011
    Inventors: Louis V. Kirchhoff, Keiko Otsu
  • Recombinant Polypeptides for Diagnosing Infection with Trypanosoma Cruzi
    Publication number: 20100196933
    Abstract: Recombinant polypeptides are disclosed that are useful for diagnosing American trypanosomiasis, or Chagas disease, a disease caused by the infectious agent Trypanosoma cruzi. Preferably, DNA sequences encoding the recombinant proteins are placed in plasmid vectors to be expressed in an organism.
    Type: Application
    Filed: January 16, 2009
    Publication date: August 5, 2010
    Inventors: Louis V. Kirchhoff, Keiko Otsu
  • Recombinant polypeptides for diagnosing infection with
    Patent number: 7491515
    Abstract: Recombinant polypeptides are disclosed that are useful for diagnosing American trypanosomiasis, or Chagas disease, a disease caused by the infectious agent Trypanosoma cruzi. Preferably, DNA sequences encoding the recombinant proteins are placed in plasmid vectors to be expressed in an organism.
    Type: Grant
    Filed: December 4, 2003
    Date of Patent: February 17, 2009
    Inventors: Louis V. Kirchhoff, Keiko Otsu
  • Recombinant polypeptides for diagnosing infection with Trypanosoma cruzi
    Publication number: 20040132077
    Abstract: Recombinant polypeptides are disclosed that are useful for diagnosing American trypanosomiasis, or Chagas disease, a disease caused by the infectious agent Trypanosoma cruzi. Preferably, DNA sequences encoding the recombinant proteins are placed in plasmid vectors to be expressed in an organism.
    Type: Application
    Filed: December 4, 2003
    Publication date: July 8, 2004
    Inventors: Louis V. Kirchhoff, Keiko Otsu
  • Polypeptides for diagnosing infection with trypanosoma cruzi
    Patent number: 6228601
    Abstract: Polypeptides are disclosed that are useful for diagnosing American trypanosomiasis, or Chagas disease, a disease caused by the infectious agent Trypanosoma cruzi. The polypeptides have a sequence that corresponds to the amino acid sequence of at least one of the C-terminal and N-terminal nonrepetitive regions of TCR27 protein. The polypeptide additionally may comprise an amino acid sequence of one or more repeats from the central region of TCR27 protein. In a preferred embodiment, the polypeptide corresponds to the N-terminal nonrepetitive region of TCR27 protein and at least one repeat from the central region of TCR27 protein, and does not correspond to the C-terminal nonrepetitive region. The polypeptides may further comprise a linker sequence at either the N-terminus or the C-terminus to facilitate attachment or conjugation to a carrier molecule in a liquid or solid support system for use in a sensitive assay for detecting T. cruzi infection.
    Type: Grant
    Filed: July 15, 1998
    Date of Patent: May 8, 2001
    Inventors: Louis V. Kirchhoff, Keiko Otsu
  • Polypeptides for diagnosing infection with Trypanosoma cruzi
    Patent number: 5876734
    Abstract: Polypeptides are disclosed that are useful for diagnosing American trypanosomiasis, or Chagas disease, a disease caused by the infectious agent Trypanosoma cruzi. The polypeptides have a sequence that corresponds to the amino acid sequence of at least one of the C-terminal and N-terminal nonrepetitive regions of TCR27 protein. The polypeptide additionally may comprise an amino acid sequence of one or more repeats from the central region of TCR27 protein. In a preferred embodiment, the polypeptide corresponds to the N-terminal nonrepetitive region of TCR27 protein and at least one repeat from the central region of TCR27 protein, and does not correspond to the C-terminal nonrepetitive region. The polypeptides may further comprise a linker sequence at either the N-terminus or the C-terminus to facilitate attachment or conjugation to a carrier molecule in a liquid or solid support system for use in a sensitive assay for detecting T. cruzi infection.
    Type: Grant
    Filed: March 24, 1994
    Date of Patent: March 2, 1999
    Inventors: Louis V. Kirchhoff, Keiko Otsu