Patents by Inventor Louise Wallace

Louise Wallace has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220033798
    Abstract: The present invention provides methods and compositions comprising at least one neutral metalloprotease enzyme that has improved storage stability. In some embodiments, the neutral metalloprotease finds use in cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions comprising neutral metalloprotease(s) obtained from Bacillus sp. In some more particularly preferred embodiments, the neutral metalloprotease is obtained from B. amyloliquefaciens. In still further preferred embodiments, the neutral metalloprotease is a variant of the B. amyloliquefaciens neutral metalloprotease. In yet additional embodiments, the neutral metalloprotease is a homolog of the the B. amyloliquefaciens neutral metalloprotease. The present invention finds particular use in applications including, but not limited to cleaning, bleaching and disinfecting.
    Type: Application
    Filed: July 15, 2021
    Publication date: February 3, 2022
    Inventors: ANDREW SHAW, DAVID A. ESTELL, EUGENE S. SADLOWSKI, HIROSHI OH, LOUISE WALLACE, RONALDUS WILHEMUS JOANNES HOMMES, SANG-KYU LEE
  • Patent number: 11091750
    Abstract: The present invention provides methods and compositions comprising at least one neutral metalloprotease enzyme that has improved storage stability. In some embodiments, the neutral metalloprotease finds use in cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions comprising neutral metalloprotease(s) obtained from Bacillus sp. In some more particularly preferred embodiments, the neutral metalloprotease is obtained from B. amyloliquefaciens. In still further preferred embodiments, the neutral metalloprotease is a variant of the B. amyloliquefaciens neutral metalloprotease. In yet additional embodiments, the neutral metalloprotease is a homolog of the the B. amyloliquefaciens neutral metalloprotease. The present invention finds particular use in applications including, but not limited to cleaning, bleaching and disinfecting.
    Type: Grant
    Filed: October 30, 2019
    Date of Patent: August 17, 2021
    Assignee: DANISCO US INC
    Inventors: Andrew Shaw, David A Estell, Eugene S Sadlowski, Hiroshi Oh, Louise Wallace, Ronaldus Wilhelmus Joannes Hommes, Sang-Kyu Lee
  • Publication number: 20200231908
    Abstract: The present invention provides methods and compositions comprising at least one neutral metalloprotease enzyme that has improved stability in the presence of a metal chelator. In some embodiments, the neutral metalloprotease finds use in cleaning and other applications comprising citrate. In some particularly preferred embodiments, the present invention provides methods and compositions comprising variant neutral metalloprotease(s) engineered to resist citrate-induced autolysis.
    Type: Application
    Filed: February 24, 2020
    Publication date: July 23, 2020
    Inventors: RONALDUS W. J. HOMMES, Louise Wallace, Andrew Shaw, Amy D. Liu
  • Patent number: 10577595
    Abstract: The present invention provides methods and compositions comprising at least one neutral metalloprotease enzyme that has improved storage stability. In some embodiments, the neutral metalloprotease finds use in cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions comprising neutral metalloprotease(s) obtained from Bacillus sp. In some more particularly preferred embodiments, the neutral metalloprotease is obtained from B. amyloliquefaciens. In still further preferred embodiments, the neutral metalloprotease is a variant of the B. amyloliquefaciens neutral metalloprotease. In yet additional embodiments, the neutral metalloprotease is a homolog of the the B. amyloliquefaciens neutral metalloprotease. The present invention finds particular use in applications including, but not limited to cleaning, bleaching and disinfecting.
    Type: Grant
    Filed: October 19, 2017
    Date of Patent: March 3, 2020
    Assignee: DANISCO US INC
    Inventors: Andrew Shaw, David A Estell, Eugene S Sadlowski, Hiroshi Oh, Louise Wallace, Ronaldus Wilhelmus Joannes Hommes, Sang-Kyu Lee
  • Publication number: 20200056165
    Abstract: The present invention provides methods and compositions comprising at least one neutral metalloprotease enzyme that has improved storage stability. In some embodiments, the neutral metalloprotease finds use in cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions comprising neutral metalloprotease(s) obtained from Bacillus sp. In some more particularly preferred embodiments, the neutral metalloprotease is obtained from B. amyloliquefaciens. In still further preferred embodiments, the neutral metalloprotease is a variant of the B. amyloliquefaciens neutral metalloprotease. In yet additional embodiments, the neutral metalloprotease is a homolog of the the B. amyloliquefaciens neutral metalloprotease. The present invention finds particular use in applications including, but not limited to cleaning, bleaching and disinfecting.
    Type: Application
    Filed: October 30, 2019
    Publication date: February 20, 2020
    Inventors: ANDREW SHAW, DAVID A ESTELL, EUGENE S SADLOWSKI, HIROSHI OH, LOUISE WALLACE, RONALDUS WILHELMUS JOAN HOMMES, SANG-KYU LEE
  • Publication number: 20180094216
    Abstract: The present invention provides methods and compositions comprising at least one neutral metalloprotease enzyme that has improved stability in the presence of a metal chelator. In some embodiments, the neutral metalloprotease finds use in cleaning and other applications comprising citrate. In some particularly preferred embodiments, the present invention provides methods and compositions comprising variant neutral metalloprotease(s) engineered to resist citrate-induced autolysis.
    Type: Application
    Filed: December 7, 2017
    Publication date: April 5, 2018
    Inventors: Ronaldus W.J. Hommes, Louise Wallace, Andrew Shaw, Amy D. Liu
  • Publication number: 20180066244
    Abstract: The present invention provides methods and compositions comprising at least one neutral metalloprotease enzyme that has improved storage stability. In some embodiments, the neutral metalloprotease finds use in cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions comprising neutral metalloprotease(s) obtained from Bacillus sp. In some more particularly preferred embodiments, the neutral metalloprotease is obtained from B. amyloliquefaciens. In still further preferred embodiments, the neutral metalloprotease is a variant of the B. amyloliquefaciens neutral metalloprotease. In yet additional embodiments, the neutral metalloprotease is a homolog of the the B. amyloliquefaciens neutral metalloprotease. The present invention finds particular use in applications including, but not limited to cleaning, bleaching and disinfecting.
    Type: Application
    Filed: October 19, 2017
    Publication date: March 8, 2018
    Inventors: ANDREW SHAW, DAVID A ESTELL, EUGENE S SADLOWSKI, HIROSHI OH, LOUISE WALLACE, RONALDUS WILHELMUS JOANNES HOMMES, SANG-KYU LEE
  • Publication number: 20170022490
    Abstract: The present invention provides methods and compositions comprising at least one neutral metalloprotease enzyme that has improved storage stability. In some embodiments, the neutral metalloprotease finds use in cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions comprising neutral metalloprotease(s) obtained from Bacillus sp. In some more particularly preferred embodiments, the neutral metalloprotease is obtained from B. amyloliquefaciens. In still further preferred embodiments, the neutral metalloprotease is a variant of the B. amyloliquefaciens neutral metalloprotease. In yet additional embodiments, the neutral metalloprotease is a homolog of the the B. amyloliquefaciens neutral metalloprotease. The present invention finds particular use in applications including, but not limited to cleaning, bleaching and disinfecting.
    Type: Application
    Filed: April 8, 2016
    Publication date: January 26, 2017
    Applicant: Danisco US Inc.
    Inventors: Andrew Shaw, Louise Wallace, David A. Estell, Ronaldus W.J. Hommes, Sang-Kyu Lee, Hiroshi Oh, Eugene S. Sadlowski
  • Patent number: 9523087
    Abstract: The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having improved expression, activity and/or stability. Also described are nucleic acids encoding the cellulase variants, compositions comprising the cellulase variants, and methods of use thereof.
    Type: Grant
    Filed: February 25, 2014
    Date of Patent: December 20, 2016
    Assignee: DANISCO US INC
    Inventors: Wolfgang Aehle, Richard R. Bott, Benjamin S. Bower, Jonathan Caspi, David A. Estell, Frits Goedegebuur, Ronaldus Wilhelmus Joannes Hommes, Thijs Kaper, Bradley R. Kelemen, Slavko Kralj, Johannes Franciscus Thomas Van Lieshout, Igor Nikolaev, Sander Van Stigt Thans, Louise Wallace, Gudrun Vogtentanz, Mats Sandgren
  • Patent number: 9334467
    Abstract: The present invention provides methods and compositions comprising at least one neutral metalloprotease enzyme that has improved storage stability. In some embodiments, the neutral metalloprotease finds use in cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions comprising neutral metalloprotease(s) obtained from Bacillus sp. In some more particularly preferred embodiments, the neutral metalloprotease is obtained from B. amyloliquefaciens. In still further preferred embodiments, the neutral metalloprotease is a variant of the B. amyloliquefaciens neutral metalloprotease. In yet additional embodiments, the neutral metalloprotease is a homolog of the the B. amyloliquefaciens neutral metalloprotease. The present invention finds particular use in applications including, but not limited to cleaning, bleaching and disinfecting.
    Type: Grant
    Filed: September 26, 2013
    Date of Patent: May 10, 2016
    Assignee: Danisco US Inc.
    Inventors: Andrew Shaw, Louise Wallace, David A. Estell, Ronaldus W. J. Hommes, Sang-Kyu Lee, Hiroshi Oh, Eugene S. Sadlowski
  • Publication number: 20160010129
    Abstract: Alpha-amylases from Bacillus subtilis (AmyE), variants thereof, nucleic acids encoding the same, and host cells comprising the nucleic acids are provided. Methods of using AmyE or variants thereof are disclosed, including liquefaction and/or saccharification of starch. Such methods may yield sugars useful for ethanol production or high fructose corn syrup production. In some cases, the amylases can be used at low pH, in the absence of calcium, and/or in the absence of a glucoamylase.
    Type: Application
    Filed: June 17, 2015
    Publication date: January 14, 2016
    Inventors: William A. Cuevas, Sang-Kyu Lee, Sandra W. Ramer, Andrew Shaw, Amr R. Toppozada, David A. Estell, Louise Wallace, Regina Chin, Carol A. Requadt, Scott D. Power, Michael J. Pepsin
  • Patent number: 9090887
    Abstract: Alpha-amylases from Bacillus subtilis (AmyE), variants thereof, nucleic acids encoding the same, and host cells comprising the nucleic acids are provided. Methods of using AmyE or variants thereof are disclosed, including liquefaction and/or saccharification of starch. Such methods may yield sugars useful for ethanol production or high fructose corn syrup production. In some cases, the amylases can be used at low pH, in the absence of calcium, and/or in the absence of a glucoamylase.
    Type: Grant
    Filed: June 5, 2009
    Date of Patent: July 28, 2015
    Assignee: DANISCO US INC.
    Inventors: William A Cuevas, Sang-Kyu Lee, Sandra W Ramer, Andrew Shaw, Amr R Toppozada, David E Estell, Louise Wallace, Regina Chin, Carol A Requadt, Scott D Power, Michael J Pepsin
  • Patent number: 9040278
    Abstract: An ?-amylase from Bacillus subtilis (AmyE) produces significant amounts of glucose from various carbohydrate substrates, including vegetable starch, maltoheptaose, and maltotriose. Among other things, this advantageous property allows AmyE or variants thereof to be used in a saccharification reaction having a reduced or eliminated requirement for glucoamylase. The reduction or elimination of the glucoamylase requirement significantly improves the efficiency of the production of ethanol or high fructose corn syrup, for example.
    Type: Grant
    Filed: June 4, 2009
    Date of Patent: May 26, 2015
    Assignee: DANISCO US INC.
    Inventors: Luis G. Cascao-Pereira, Regina Chin, William A. Cuevas, David A. Estell, Sang-Kyu Lee, Michael J. Pepsin, Scott D. Power, Sandra W. Ramer, Carol A. Requadt, Andrew Shaw, Amr R. Toppozada, Louise Wallace
  • Patent number: 8975056
    Abstract: Alpha-amylases from Bacillus subtilis (AmyE), variants thereof, nucleic acids encoding the same, and host cells comprising the nucleic acids are provided. Methods of using AmyE or variants thereof are disclosed, including liquefaction and/or saccharification of starch. Such methods may yield sugars useful for ethanol production or high fructose corn syrup production. In some cases, the amylases can be used at low pH, in the absence of calcium, and/or in the absence of a glucoamylase.
    Type: Grant
    Filed: October 25, 2012
    Date of Patent: March 10, 2015
    Assignee: Danisco US Inc.
    Inventors: Luis G. Cascao-Pereira, William A. Cuevas, David A. Estell, Sang-Kyu Lee, Scott D. Power, Sandra W. Ramer, Amr Toppozada, Louise Wallace
  • Publication number: 20140315775
    Abstract: The present invention provides methods and compositions comprising at least one neutral metalloprotease enzyme that has improved stability in the presence of a metal chelator. In some embodiments, the neutral metalloprotease finds use in cleaning and other applications comprising citrate. In some particularly preferred embodiments, the present invention provides methods and compositions comprising variant neutral metalloprotease(s) engineered to resist citrate-induced autolysis.
    Type: Application
    Filed: February 24, 2014
    Publication date: October 23, 2014
    Applicant: Danisco US Inc.
    Inventors: RONALDUS W.J. HOMMES, AMY D. LIU, ANDREW SHAW, LOUISE WALLACE
  • Publication number: 20140302585
    Abstract: The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having improved expression, activity and/or stability. Also described are nucleic acids encoding the cellulase variants, compositions comprising the cellulase variants, and methods of use thereof.
    Type: Application
    Filed: February 25, 2014
    Publication date: October 9, 2014
    Applicant: DANISCO US INC.
    Inventors: Wolfgang AEHLE, Richard R. BOTT, Benjamin S. BOWER, Jonathan CASPI, David A. ESTELL, Frits GOEDEGEBUUR, Ronaldus Wilhelmus HOMMES, Thijs KAPER, Bradley R. KELEMEN, Slavko KRALJ, Johannes Franciscus Thomas VAN LIESHOUT, Igor NIKOLAEV, Sander VAN STIGT THANS, Louise WALLACE, Gudrun VOGTENTANZ, Mats SANDGREN
  • Publication number: 20140134708
    Abstract: The present invention provides methods and compositions comprising at least one neutral metalloprotease enzyme that has improved storage stability. In some embodiments, the neutral metalloprotease finds use in cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions comprising neutral metalloprotease(s) obtained from Bacillus sp. In some more particularly preferred embodiments, the neutral metalloprotease is obtained from B. amyloliquefaciens. In still further preferred embodiments, the neutral metalloprotease is a variant of the B. amyloliquefaciens neutral metalloprotease. In yet additional embodiments, the neutral metalloprotease is a homolog of the B. amyloliquefaciens neutral metalloprotease. The present invention finds particular use in applications including, but not limited to cleaning, bleaching and disinfecting.
    Type: Application
    Filed: September 26, 2013
    Publication date: May 15, 2014
    Applicant: Danisco US Inc.
    Inventors: Andrew Shaw, Louise Wallace, David A. Estell, Ronaldus W.J. Hommes, Sang-Kyu Lee, Hiroshi Oh, Eugene S. Sadlowski
  • Patent number: 8679816
    Abstract: The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having improved expression, activity and/or stability. Also described are nucleic acids encoding the cellulase variants, compositions comprising the cellulase variants, and methods of use thereof.
    Type: Grant
    Filed: June 3, 2010
    Date of Patent: March 25, 2014
    Assignee: Danisco US Inc.
    Inventors: Wolfgang Aehle, Richard R. Bott, Benjamin Bower, Jonathan Caspi, David A. Estell, Frits Goedegebuur, Ronaldus W. J. Hommes, Thijs Kaper, Bradley Kelemen, Slavko Kralj, Johan Van Lieshout, Igor Nikolaev, Sander Van Stigt Thans, Louise Wallace, Gudrun Vogtentanz, Mats Sandgren
  • Patent number: 8574884
    Abstract: The present invention provides methods and compositions comprising at least one neutral metalloprotease enzyme that has improved storage stability. In some embodiments, the neutral metalloprotease finds use in cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions comprising neutral metalloprotease(s) obtained from Bacillus sp. In some more particularly preferred embodiments, the neutral metalloprotease is obtained from B. amyloliquefaciens. In still further preferred embodiments, the neutral metalloprotease is a variant of the B. amyloliquefaciens neutral metalloprotease. In yet additional embodiments, the neutral metalloprotease is a homolog of the B. amyloliquefaciens neutral metalloprotease. The present invention finds particular use in applications including, but not limited to cleaning, bleaching and disinfecting.
    Type: Grant
    Filed: January 6, 2012
    Date of Patent: November 5, 2013
    Assignee: Danisco US Inc.
    Inventors: Andrew Shaw, Louise Wallace, David A. Estell, Ronaldus W. J. Hommes, Sang-Kyu Lee, Hiroshi Oh, Eugene S. Sadlowski
  • Patent number: 8323945
    Abstract: Alpha-amylases from Bacillus subtilis (AmyE), variants thereof, nucleic acids encoding the same, and host cells comprising the nucleic acids are provided. Methods of using AmyE or variants thereof are disclosed, including liquefaction and/or saccharification of starch. Such methods may yield sugars useful for ethanol production or high fructose corn syrup production. In some cases, the amylases can be used at low pH, in the absence of calcium, and/or in the absence of a glucoamylase.
    Type: Grant
    Filed: June 5, 2009
    Date of Patent: December 4, 2012
    Assignee: Danisco US Inc.
    Inventors: Luis G. Cascao-Pereira, William A. Cuevas, David A. Estell, Sang-Kyu Lee, Scott D. Power, Sandra W. Ramer, Amr Toppozada, Louise Wallace