Patents by Inventor Louiza Konstanti

Louiza Konstanti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Water dispersible mini-tablets comprising Enalapril for treatment of hypertension in a pediatric population and method of preparation thereof
    Patent number: 11318114
    Abstract: The present invention relates to water dispersible mini-tablets of Enalapril or a pharmaceutically acceptable salt thereof for use in the treatment of hypertension in a pediatric population. The pediatric population is defined as 0 to 18 years of age. The water dispersible mini-tablets of Enalapril further include a disintegrant, a diluent, a lubricant and a glidant. The active ingredient is distributed evenly in the mini-tablet and the disintegrant comprises Crospovidone. The mini-tablet has a diameter of 3 mm and disintegrates in less than 15 seconds in water.
    Type: Grant
    Filed: June 19, 2015
    Date of Patent: May 3, 2022
    Assignee: PHARMATHEN S.A.
    Inventors: Evangelos Karavas, Efthymios Koutris, Vasiliki Samara, Ioanna Koutri, Anastasia Kalaskani, Lida Kalantzi, Andreas Kakouris, Amalia Diakidou, George Gotzamanis, Zaharias Georgousis, Louiza Konstanti
  • Orodispersible film composition comprising enalapril for the treatment of hypertension in a pediatric population
    Patent number: 11154585
    Abstract: The present invention relates to an oral applicable therapeutic dosage form, in particular an orodispersible film comprising Enalapril or pharmaceutically acceptable salts thereof for use in the treatment of hypertension in a pediatric population. The pediatric population is defined from 1 to 18 years of age. The present invention also provides a method of manufacturing of such a dosage form.
    Type: Grant
    Filed: July 29, 2020
    Date of Patent: October 26, 2021
    Assignee: PHARMATHEN S.A.
    Inventors: Evangelos Karavas, Efthymios Koutris, Vasiliki Samara, Ioanna Koutri, Anastasia Kalaskani, Lida Kalantzi, Andreas Kakouris, Amalia Diakidou, George Gotzamanis, Zaharias Georgousis, Louiza Konstanti
  • ORODISPERSIBLE FILM COMPOSITION COMPRISING ENALAPRIL FOR THE TREATMENT OF HYPERTENSION IN A PEDIATRIC POPULATION
    Publication number: 20200360461
    Abstract: The present invention relates to an oral applicable therapeutic dosage form, in particular an orodispersible film comprising Enalapril or pharmaceutically acceptable salts thereof for use in the treatment of hypertension in a pediatric population. The pediatric population is defined from 1 to 18 years of age. The present invention also provides a method of manufacturing of such a dosage form.
    Type: Application
    Filed: July 29, 2020
    Publication date: November 19, 2020
    Inventors: EVANGELOS KARAVAS, EFTHYMIOS KOUTRIS, VASILIKI SAMARA, IOANNA KOUTRI, ANASTASIA KALASKANI, LIDA KALANTZI, ANDREAS KAKOURIS, AMALIA DIAKIDOU, GEORGE GOTZAMANIS, ZAHARIAS GEORGOUSIS, LOUIZA KONSTANTI
  • STABLE INJECTABLE PHARMACEUTICAL COMPOSITION OF NEUROKININ 1 RECEPTOR ANTAGONIST AND PROCESS FOR PREPARATION THEREOF
    Publication number: 20200237920
    Abstract: The present invention relates to a controlled release sterile injectable formulation in the form of solution, suspension or sol-gel formulation for intramuscular or subcutaneous administration comprising a therapeutically effective amount of a neurokinin 1 receptor antagonist, in particular Aprepitant or Fosaprepitant or pharmaceutical acceptable salt, derivative or metabolite thereof. It also relates to a process for developing such formulations.
    Type: Application
    Filed: April 17, 2020
    Publication date: July 30, 2020
    Applicant: PHARMATHEN S.A.
    Inventors: EVANGELOS KARAVAS, EFTHIMIOS KOUTRIS, DIMITRIOS BIKIARIS, SOTIRIA CHATIDOU, AMALIA DIAKIDOU, PANAGIOTIS BARMPALEXIS, LOUIZA KONSTANTI, KATERINA MINIOTI
  • WATER DISPERSIBLE MINI-TABLETS COMPRISING ENALAPRIL FOR TREATMENT OF HYPERTENSION IN A PEDIATRIC POPULATION AND METHOD OF PREPARATION THEREOF
    Publication number: 20170202804
    Abstract: The present invention relates to water dispersible mini-tablets of Enalapril or a pharmaceutically acceptable salt thereof for use in the treatment of hypertension in a pediatric formulation. The pediatric formulation is defined as 0 to 18 years of age. The present invention also provides a method of manufacturing of such dosage form.
    Type: Application
    Filed: June 19, 2015
    Publication date: July 20, 2017
    Applicant: PHARMATHEN S.A.
    Inventors: EVANGELOS KARAVAS, EFTHYMIOS KOUTRIS, VASILIKI SAMARA, IOANNA KOUTRI, ANASTASIA KALASKANI, LIDA KALANTZI, ANDREAS KAKOURIS, AMALIA DIAKIDOU, GEORGE GOTZAMANIS, ZAHARIAS GEORGOUSIS, LOUIZA KONSTANTI
  • ORODISPERSIBLE FILM COMPOSITION COMPRISING ENALAPRIL FOR THE TREATMENT OF HYPERTENSION IN A PEDIATRIC POPULATION
    Publication number: 20170165315
    Abstract: The present invention relates to an oral applicable therapeutic dosage form, in particular an orodispersible film comprising Enalapril or pharmaceutically acceptable salts thereof for use in the treatment of hypertension in a pediatric population. The pediatric population is defined from 1 to 18 years of age. The present invention also provides a method of manufacturing of such a dosage form.
    Type: Application
    Filed: June 19, 2015
    Publication date: June 15, 2017
    Applicant: PHARMATHEN S.A.
    Inventors: EVANGELOS KARAVAS, EFTHYMIOS KOUTRIS, VASILIKI SAMARA, IOANNA KOUTRI, ANASTASIA KALASKANI, LIDA KALANTZI, ANDREAS KAKOURIS, AMALIA DIAKIDOU, GEORGE GOTZAMANIS, ZAHARIAS GEORGOUSIS, LOUIZA KONSTANTI
  • STABLE INJECTABLE PHARMACEUTICAL COMPOSITION OF NEUROKININ 1 RECEPTOR ANTAGONIST AND PROCESS FOR PREPARATION THEREOF
    Publication number: 20150165045
    Abstract: The present invention relates to a controlled release sterile injectable formulation in the form of solution, suspension or sol-gel formulation for intramuscular or subcutaneous administration comprising a therapeutically effective amount of a neurokinin 1 receptor antagonist, in particular Aprepitant or Fosaprepitant or pharmaceutical acceptable salt, derivative or metabolite thereof. It also relates to a process for developing such formulations.
    Type: Application
    Filed: July 6, 2012
    Publication date: June 18, 2015
    Applicant: PHARMATHEN S.A.
    Inventors: Evangelos Karavas, Efthimios Koutris, Dimitrios Bikiaris, Sotiria Chatidou, Amalia Diakidou, Panagiotis Barmpalexis, Louiza Konstanti, Katerina Minioti