Patents by Inventor Loyd V. Allen

Loyd V. Allen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6567693
    Abstract: A conducting silicone matrix incorporating a suspension of a drug in ionized and non-ionized phases in an emulsion of a hydrophobic polymer. In one version, the drug is prepared as a concentrated aqueous suspension incorporated in a silicone matrix with a silicone surfactant. An electrolyte may be incorporated into the silicone matrix for increasing its conductivity. When a current is applied, the drug in individual globules in the drug suspension migrates away from the electrode and becomes concentrated at the distal side of the globules eventually resulting in an increase in the drug concentration distal to the electrode and adjacent to the skin and thereby resulting in transfer of the active drug through the skin. This system provides a matrix with minimal electroendosmotic flow that is current efficient and provides a drug reservoir that can last for several days during application of the drug.
    Type: Grant
    Filed: June 15, 2000
    Date of Patent: May 20, 2003
    Assignee: The Board of Regents of the University of Oklahoma
    Inventor: Loyd V. Allen, Jr.
  • Publication number: 20020009490
    Abstract: This invention described herein discloses an antiviral therapeutic composition. This antiviral therapeutic composition can be used to treat human viral infections.
    Type: Application
    Filed: December 22, 2000
    Publication date: January 24, 2002
    Inventors: Travis R. Benkendorfer, Loyd V. Allen
  • Patent number: 6207199
    Abstract: A particulate support matrix, and a dosage form made therefrom, and processes for making such support matrices and dosage forms, which disintegrate or dissolve in a matter of just a few seconds once placed into an aqueous environment. First, a porous particulate powder matrix comprising at least two polymeric components which will serve as the dosage form matrix is produced. The polymeric components have different solubilities. In a second step, a pharmaceutical compound, for example an antihistamine, decongestant, or antibiotic is combined with the powder. Other additives may also be added to the mixture. In a third step the mixture is formed into a dosage form. Finally, in a fourth step, a coating may be formed upon the outer surface of the dosage form to enhance the intactness and durability of the dosage form.
    Type: Grant
    Filed: July 6, 1998
    Date of Patent: March 27, 2001
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Loyd V. Allen, Bingnan Wang
  • Patent number: 6187337
    Abstract: A particulate support matrix, and a dosage form made therefrom, and processes for making such support matrices and dosage forms, which disintegrate or dissolve in a matter of just a few seconds once placed into an aqueous environment. First, a porous particulate powder matrix comprising at least two polymeric components which will serve as the dosage form matrix is produced. The polymeric components have different solubilities. In a second step, a pharmaceutical compound, for example an antihistamine, decongestant, or antibiotic is combined with the powder. Other additives may also be added to the mixture. In a third step the mixture is formed into a dosage form. Finally, in a fourth step, a coating may be formed upon the outer surface of the dosage form to enhance the intactness and durability of the dosage form.
    Type: Grant
    Filed: July 6, 1998
    Date of Patent: February 13, 2001
    Assignees: The Board of Regents of the University of Oklahoma, Janssen Pharmaceutica
    Inventors: Loyd V. Allen, Bingnan Wang, John Desmond Davies
  • Patent number: 6177104
    Abstract: A particulate support matrix, and a dosage form made therefrom, and processes for making such support matrices and dosage forms, which disintegrate or dissolve in a matter of just a few seconds once placed into an aqueous environment. First, a porous particulate powder matrix comprising at least two polymeric components which will serve as the dosage form matrix is produced. The polymeric components have different solubilities. In a second step, a pharmaceutical compound, for example an antihistamine, decongestant, or antibiotic is combined with the powder. Other additives may also be added to the mixture. In a third step the mixture is formed into a dosage form. Finally, in a fourth step, a coating may be formed upon the outer surface of the dosage form to enhance the intactness and durability of the dosage form.
    Type: Grant
    Filed: July 6, 1998
    Date of Patent: January 23, 2001
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Loyd V. Allen, Bingnan Wang
  • Patent number: 6119036
    Abstract: A conducting silicone matrix incorporating a suspension of a drug in ionized and non-ionized phases in an emulsion of a hydrophobic polymer. In one version, the drug is prepared as a concentrated aqueous suspension incorporated in a silicone matrix with a silicone surfactant. An electrolyte may be incorporated into the silicone matrix for increasing its conductivity. When a current is applied, the drug in individual globules in the drug suspension migrates away from the electrode and becomes concentrated at the distal side of the globules eventually resulting in an increase in the drug concentration distal to the electrode and adjacent to the skin and thereby resulting in transfer of the active drug through the skin. This system provides a matrix with minimal electroendosmotic flow that is current efficient and provides a drug reservoir that can last for several days during application of the drug.
    Type: Grant
    Filed: March 24, 1998
    Date of Patent: September 12, 2000
    Assignee: The Board of Regents of the University of Oklahoma
    Inventor: Loyd V. Allen, Jr.
  • Patent number: 6066337
    Abstract: A particulate support matrix, and a dosage form made therefrom, and processes for making such support matrices and dosage forms, which disintegrate or dissolve in a matter of just a few seconds once placed into an aqueous environment. First, a porous particulate powder matrix which will serve as the dosage form matrix is produced. In a second step, the pharmaceutical, for example an antihistamine, decongestant, or antibiotic is combined with the powder. Other additives may also be added to the mixture. In a third step the mixture is formed into a dosage form. Finally, in a fourth step, a coating may be formed upon the outer surface of the dosage form to enhance the intactness and durability of the dosage form.
    Type: Grant
    Filed: July 6, 1998
    Date of Patent: May 23, 2000
    Assignee: The Board of Regents of the University of Oklahoma and Janssen Pharmaceutica, Inc.
    Inventors: Loyd V. Allen, Bingnan Wang, John Desmond Davies
  • Patent number: 5807576
    Abstract: The present invention comprises a tablet, and method for making such, which disintegrates or dissolves in a matter of just a few seconds once placed into the oral cavity. Generally, the method of the present invention comprises up to four steps. First, a porous particulate powder which will serve as the tablet support matrix is produced. In the second step, the pharmaceutical, for example an antihistamine, decongestant, or antibiotic is combined with the powder. Other additives may also be added to the mixture. In the third step the mixture is formed into a tablet. Finally, in the fourth step, a coating may be applied to the outer surface of the tablet to enhance the intactness and durability of the tablet.
    Type: Grant
    Filed: February 3, 1994
    Date of Patent: September 15, 1998
    Assignees: The Board of Regents of the University of Oklahoma, Janssen Pharmaceutica, Inc.
    Inventors: Loyd V. Allen, Jr., Bingnan Wang, John Desmond Davies
  • Patent number: 5776491
    Abstract: The present invention concerns a particulate support matrix, a solid dosage form made therefrom, and processes for making such support matrices and dosage forms, which disintegrate or dissolve in a matter of just a few seconds once placed into the oral cavity.First, a porous particulate powder which will serve as the tablet support matrix is produced. In the second step, the pharmaceutical, for example an antihistamine, decongestant, or antibiotic is combined with the powder. Other additives may also be added to the mixture. In the third step the mixture is formed into a tablet. Finally, in the fourth step, a coating may be applied to the outer surface of the tablet to enhance the intactness and durability of the tablet.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: July 7, 1998
    Assignees: The Board of Regents of the University of Oklahoma, Janssen Pharmaceutica, Inc.
    Inventors: Loyd V. Allen, Jr., Bingnan Wang, John Desmond Davies
  • Patent number: 5635210
    Abstract: The present invention comprises a tablet, and method for making such, which disintegrates or dissolves in a matter of just a few seconds once placed into the oral cavity. Generally, the method of the present invention comprises up to four steps. First, a porous particulate powder which will serve as the tablet support matrix is produced. In the second step, the pharmaceutical, for example an antihistamine, decongestant, or antibiotic is combined with the powder. Other additives may also be added to the mixture. In the third step the mixture is formed into a tablet. Finally, in the fourth step, a coating may be applied to the outer surface of the tablet to enhance the intactness and durability of the tablet.
    Type: Grant
    Filed: December 8, 1994
    Date of Patent: June 3, 1997
    Assignees: The Board of Regents of the University of Oklahoma, Janssen Pharmaceutica, Inc.
    Inventors: Loyd V. Allen, Jr., Bingnan Wang, John D. Davies
  • Patent number: 5595761
    Abstract: The present invention comprises a particulate support matrix for making a solid tablet form, and method for making such, which disintegrates or dissolves in a matter of just a few seconds once placed into the oral cavity. Thee particulate support matrix comprises a first polymeric component which may be a polypeptide, preferably a non-hydrolyzed gelatin, a second polymeric component which may be a different polypeptide which may be a hydrolyzed gelatin and a bulking agent. The porous particulate powder can serve as the tablet support matrix, to which a pharmaceutical, for example an antihistamine, decongestant, or antibiotic is added.
    Type: Grant
    Filed: January 27, 1994
    Date of Patent: January 21, 1997
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Loyd V. Allen, Jr., Bingnan Wang
  • Patent number: 5587180
    Abstract: The present invention comprises a particulate support matrix for making a tablet, and method for making such, which disintegrates or dissolves in a matter of just a few seconds once placed into the oral cavity. Thee particulate support matrix comprises a first polymeric component which may be a polypeptide, preferably a non-hydrolyzed gelatin, a second polymeric component which may be a different polypeptide which may be a hydrolyzed gelatin and a bulking agent. The porous particulate powder can serve as the tablet support matrix, to which a pharmaceutical, for example an antihistamine, decongestant, or antibiotic is added.
    Type: Grant
    Filed: December 8, 1994
    Date of Patent: December 24, 1996
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Loyd V. Allen, Jr., Bingnan Wang
  • Patent number: 5466695
    Abstract: This invention relates to a method of applying a cationic derivative of Minoxidil which is transported by means of iontophoresis to hair follicles where the cationic derivatives promote hair growth. Each of the cationic derivatives of Minoxidil are synthesized by reacting the Minoxidil parent compound with an organic or an inorganic acid to form the cationic derivative.
    Type: Grant
    Filed: July 11, 1994
    Date of Patent: November 14, 1995
    Assignee: Tulsa Forte Pharmacy Enterprises, Inc.
    Inventors: Charles W. Poulos, George M. Brenner, Loyd V. Allen, Jr., Vilas A. Prabhu, Pedro L. Huerta, Jr.
  • Patent number: 5103110
    Abstract: A programmable power supply having a plurality of channels wherein each channel is adapted to output a selectable DC voltage, AC voltage, DC current or AC current. Each channel is adapted to select a DC reference signal or an AC reference signal and to scale the selected DC reference or the AC reference to output the selected signal. The outputted selected signals are monitored to provide a monitored channel signal indicating the value of the selected signal. The programmable power supply outputs monitored channel signals for each of the channels in a human perceivable format such as a display or printed format. At least some of the channels are adapted to be connectable to a temperature probe which outputs temperature signals and, in this embodiment, the temperature signals are monitored to provide monitored channel temperature signals, the monitored channel temperature signals being outputted in a human perceivable format such as a display or printed format or both.
    Type: Grant
    Filed: October 20, 1989
    Date of Patent: April 7, 1992
    Assignee: Keltronics Corporation
    Inventors: Craig M. Housworth, Loyd V. Allen, Jr., Alfred W. Yakel