Patents by Inventor Loyd V. Allen
Loyd V. Allen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 6567693Abstract: A conducting silicone matrix incorporating a suspension of a drug in ionized and non-ionized phases in an emulsion of a hydrophobic polymer. In one version, the drug is prepared as a concentrated aqueous suspension incorporated in a silicone matrix with a silicone surfactant. An electrolyte may be incorporated into the silicone matrix for increasing its conductivity. When a current is applied, the drug in individual globules in the drug suspension migrates away from the electrode and becomes concentrated at the distal side of the globules eventually resulting in an increase in the drug concentration distal to the electrode and adjacent to the skin and thereby resulting in transfer of the active drug through the skin. This system provides a matrix with minimal electroendosmotic flow that is current efficient and provides a drug reservoir that can last for several days during application of the drug.Type: GrantFiled: June 15, 2000Date of Patent: May 20, 2003Assignee: The Board of Regents of the University of OklahomaInventor: Loyd V. Allen, Jr.
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Publication number: 20020009490Abstract: This invention described herein discloses an antiviral therapeutic composition. This antiviral therapeutic composition can be used to treat human viral infections.Type: ApplicationFiled: December 22, 2000Publication date: January 24, 2002Inventors: Travis R. Benkendorfer, Loyd V. Allen
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Patent number: 6207199Abstract: A particulate support matrix, and a dosage form made therefrom, and processes for making such support matrices and dosage forms, which disintegrate or dissolve in a matter of just a few seconds once placed into an aqueous environment. First, a porous particulate powder matrix comprising at least two polymeric components which will serve as the dosage form matrix is produced. The polymeric components have different solubilities. In a second step, a pharmaceutical compound, for example an antihistamine, decongestant, or antibiotic is combined with the powder. Other additives may also be added to the mixture. In a third step the mixture is formed into a dosage form. Finally, in a fourth step, a coating may be formed upon the outer surface of the dosage form to enhance the intactness and durability of the dosage form.Type: GrantFiled: July 6, 1998Date of Patent: March 27, 2001Assignee: The Board of Regents of the University of OklahomaInventors: Loyd V. Allen, Bingnan Wang
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Patent number: 6187337Abstract: A particulate support matrix, and a dosage form made therefrom, and processes for making such support matrices and dosage forms, which disintegrate or dissolve in a matter of just a few seconds once placed into an aqueous environment. First, a porous particulate powder matrix comprising at least two polymeric components which will serve as the dosage form matrix is produced. The polymeric components have different solubilities. In a second step, a pharmaceutical compound, for example an antihistamine, decongestant, or antibiotic is combined with the powder. Other additives may also be added to the mixture. In a third step the mixture is formed into a dosage form. Finally, in a fourth step, a coating may be formed upon the outer surface of the dosage form to enhance the intactness and durability of the dosage form.Type: GrantFiled: July 6, 1998Date of Patent: February 13, 2001Assignees: The Board of Regents of the University of Oklahoma, Janssen PharmaceuticaInventors: Loyd V. Allen, Bingnan Wang, John Desmond Davies
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Patent number: 6177104Abstract: A particulate support matrix, and a dosage form made therefrom, and processes for making such support matrices and dosage forms, which disintegrate or dissolve in a matter of just a few seconds once placed into an aqueous environment. First, a porous particulate powder matrix comprising at least two polymeric components which will serve as the dosage form matrix is produced. The polymeric components have different solubilities. In a second step, a pharmaceutical compound, for example an antihistamine, decongestant, or antibiotic is combined with the powder. Other additives may also be added to the mixture. In a third step the mixture is formed into a dosage form. Finally, in a fourth step, a coating may be formed upon the outer surface of the dosage form to enhance the intactness and durability of the dosage form.Type: GrantFiled: July 6, 1998Date of Patent: January 23, 2001Assignee: The Board of Regents of the University of OklahomaInventors: Loyd V. Allen, Bingnan Wang
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Patent number: 6119036Abstract: A conducting silicone matrix incorporating a suspension of a drug in ionized and non-ionized phases in an emulsion of a hydrophobic polymer. In one version, the drug is prepared as a concentrated aqueous suspension incorporated in a silicone matrix with a silicone surfactant. An electrolyte may be incorporated into the silicone matrix for increasing its conductivity. When a current is applied, the drug in individual globules in the drug suspension migrates away from the electrode and becomes concentrated at the distal side of the globules eventually resulting in an increase in the drug concentration distal to the electrode and adjacent to the skin and thereby resulting in transfer of the active drug through the skin. This system provides a matrix with minimal electroendosmotic flow that is current efficient and provides a drug reservoir that can last for several days during application of the drug.Type: GrantFiled: March 24, 1998Date of Patent: September 12, 2000Assignee: The Board of Regents of the University of OklahomaInventor: Loyd V. Allen, Jr.
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Patent number: 6066337Abstract: A particulate support matrix, and a dosage form made therefrom, and processes for making such support matrices and dosage forms, which disintegrate or dissolve in a matter of just a few seconds once placed into an aqueous environment. First, a porous particulate powder matrix which will serve as the dosage form matrix is produced. In a second step, the pharmaceutical, for example an antihistamine, decongestant, or antibiotic is combined with the powder. Other additives may also be added to the mixture. In a third step the mixture is formed into a dosage form. Finally, in a fourth step, a coating may be formed upon the outer surface of the dosage form to enhance the intactness and durability of the dosage form.Type: GrantFiled: July 6, 1998Date of Patent: May 23, 2000Assignee: The Board of Regents of the University of Oklahoma and Janssen Pharmaceutica, Inc.Inventors: Loyd V. Allen, Bingnan Wang, John Desmond Davies
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Patent number: 5807576Abstract: The present invention comprises a tablet, and method for making such, which disintegrates or dissolves in a matter of just a few seconds once placed into the oral cavity. Generally, the method of the present invention comprises up to four steps. First, a porous particulate powder which will serve as the tablet support matrix is produced. In the second step, the pharmaceutical, for example an antihistamine, decongestant, or antibiotic is combined with the powder. Other additives may also be added to the mixture. In the third step the mixture is formed into a tablet. Finally, in the fourth step, a coating may be applied to the outer surface of the tablet to enhance the intactness and durability of the tablet.Type: GrantFiled: February 3, 1994Date of Patent: September 15, 1998Assignees: The Board of Regents of the University of Oklahoma, Janssen Pharmaceutica, Inc.Inventors: Loyd V. Allen, Jr., Bingnan Wang, John Desmond Davies
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Patent number: 5776491Abstract: The present invention concerns a particulate support matrix, a solid dosage form made therefrom, and processes for making such support matrices and dosage forms, which disintegrate or dissolve in a matter of just a few seconds once placed into the oral cavity.First, a porous particulate powder which will serve as the tablet support matrix is produced. In the second step, the pharmaceutical, for example an antihistamine, decongestant, or antibiotic is combined with the powder. Other additives may also be added to the mixture. In the third step the mixture is formed into a tablet. Finally, in the fourth step, a coating may be applied to the outer surface of the tablet to enhance the intactness and durability of the tablet.Type: GrantFiled: June 7, 1995Date of Patent: July 7, 1998Assignees: The Board of Regents of the University of Oklahoma, Janssen Pharmaceutica, Inc.Inventors: Loyd V. Allen, Jr., Bingnan Wang, John Desmond Davies
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Patent number: 5635210Abstract: The present invention comprises a tablet, and method for making such, which disintegrates or dissolves in a matter of just a few seconds once placed into the oral cavity. Generally, the method of the present invention comprises up to four steps. First, a porous particulate powder which will serve as the tablet support matrix is produced. In the second step, the pharmaceutical, for example an antihistamine, decongestant, or antibiotic is combined with the powder. Other additives may also be added to the mixture. In the third step the mixture is formed into a tablet. Finally, in the fourth step, a coating may be applied to the outer surface of the tablet to enhance the intactness and durability of the tablet.Type: GrantFiled: December 8, 1994Date of Patent: June 3, 1997Assignees: The Board of Regents of the University of Oklahoma, Janssen Pharmaceutica, Inc.Inventors: Loyd V. Allen, Jr., Bingnan Wang, John D. Davies
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Patent number: 5595761Abstract: The present invention comprises a particulate support matrix for making a solid tablet form, and method for making such, which disintegrates or dissolves in a matter of just a few seconds once placed into the oral cavity. Thee particulate support matrix comprises a first polymeric component which may be a polypeptide, preferably a non-hydrolyzed gelatin, a second polymeric component which may be a different polypeptide which may be a hydrolyzed gelatin and a bulking agent. The porous particulate powder can serve as the tablet support matrix, to which a pharmaceutical, for example an antihistamine, decongestant, or antibiotic is added.Type: GrantFiled: January 27, 1994Date of Patent: January 21, 1997Assignee: The Board of Regents of the University of OklahomaInventors: Loyd V. Allen, Jr., Bingnan Wang
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Patent number: 5587180Abstract: The present invention comprises a particulate support matrix for making a tablet, and method for making such, which disintegrates or dissolves in a matter of just a few seconds once placed into the oral cavity. Thee particulate support matrix comprises a first polymeric component which may be a polypeptide, preferably a non-hydrolyzed gelatin, a second polymeric component which may be a different polypeptide which may be a hydrolyzed gelatin and a bulking agent. The porous particulate powder can serve as the tablet support matrix, to which a pharmaceutical, for example an antihistamine, decongestant, or antibiotic is added.Type: GrantFiled: December 8, 1994Date of Patent: December 24, 1996Assignee: The Board of Regents of the University of OklahomaInventors: Loyd V. Allen, Jr., Bingnan Wang
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Patent number: 5466695Abstract: This invention relates to a method of applying a cationic derivative of Minoxidil which is transported by means of iontophoresis to hair follicles where the cationic derivatives promote hair growth. Each of the cationic derivatives of Minoxidil are synthesized by reacting the Minoxidil parent compound with an organic or an inorganic acid to form the cationic derivative.Type: GrantFiled: July 11, 1994Date of Patent: November 14, 1995Assignee: Tulsa Forte Pharmacy Enterprises, Inc.Inventors: Charles W. Poulos, George M. Brenner, Loyd V. Allen, Jr., Vilas A. Prabhu, Pedro L. Huerta, Jr.
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Patent number: 5103110Abstract: A programmable power supply having a plurality of channels wherein each channel is adapted to output a selectable DC voltage, AC voltage, DC current or AC current. Each channel is adapted to select a DC reference signal or an AC reference signal and to scale the selected DC reference or the AC reference to output the selected signal. The outputted selected signals are monitored to provide a monitored channel signal indicating the value of the selected signal. The programmable power supply outputs monitored channel signals for each of the channels in a human perceivable format such as a display or printed format. At least some of the channels are adapted to be connectable to a temperature probe which outputs temperature signals and, in this embodiment, the temperature signals are monitored to provide monitored channel temperature signals, the monitored channel temperature signals being outputted in a human perceivable format such as a display or printed format or both.Type: GrantFiled: October 20, 1989Date of Patent: April 7, 1992Assignee: Keltronics CorporationInventors: Craig M. Housworth, Loyd V. Allen, Jr., Alfred W. Yakel