Abstract: The present invention provides a preparation of a Siglec-15 binding protein and the use thereof, and specifically relates to an isolated antigen-binding protein, which comprises HCDR3. Provided is the use of the antigen-binding protein in the prevention and treatment of diseases.

Abstract: Provided is an GARP protein antibody, and a cell comprising or expressing the GA RP protein antibody. The GARP protein antibody binds to human GARP/human TGF-?1 complex with a KD value of about 1.0E-12 or less. Also provided are a pharmaceutical combination comprising the GARP protein antibody and an immune checkpoint inhibitor and use thereof.

Abstract: Methods are provided for the treatment of cancer and/or fibrosis. It is shown that there is increased CD63 expression both in lung cancer and pulmonary fibrosis, sarcoma, skin fibrosis, liver cancer and liver cirrhosis, NASH and NHFLD, and kidney fibrosis from hypertension and other etiologies. Inhibiting CD63 increases phagocytosis of lung cancer cells and lung fibroblasts; and can eliminates tumor cells and pathogenic fibrosis.

Abstract: A smart insect collection device comprising: a trapping device; a sensing device having a through opening in fluid connection with the trapping device; a processing unit to receive electrical signals from the sensing device; and a collecting module comprising: a selection plate having at least one through hole configured to engage an opening of a collection container for collection of insects therein, the sensing device provided between the trapping device and the selection plate, the selection plate movable between at least one non-collecting position and at least one collecting position; and a controller in communication with the processing unit and with a motor provided to move the selection plate, the controller programmable to activate the motor to move the selection plate to the collecting position in response to the processing unit identifying an insect passing through the through opening to be an insect of a predetermined kind for collection.

Abstract: A larvae counter comprising a first container for receiving water, eggs of insects and/or larvae, a second container in fluid communication with the first container for receiving water and larvae from the first container, and a larvae counting module in fluid communication with the second container for receiving water and larvae from the second container and counting the larvae.

Abstract: The invention relates to methods and compositions for detecting colorectal cancer and colorectal polyps by measurement of metabolites in bodily fluids such as urine, including diacetylspermine and kynurenine.

Abstract: A rock direct tensile test platform suitable for all material test machines includes a support frame. A top of the support frame is fixed with a top plate, and a bearing plate is provided above the top plate. The bearing plate is provided with a plurality of vertical force transferring rods. The force transferring rods vertically penetrate through the top plate and have a sliding fit with the top plate. Lower ends of the force transferring rods are provided with a tensile base. A top of the tensile base is provided with a lower clamp holder. A bottom of the top plate is provided with an upper clamp holder, and a clamp center of the upper clamp holder coincides with a clamp center of the lower clamp holder.

Abstract: A direct tensile and acoustic testing machine under rock seepage includes a sample and a support frame. A top of the support frame is fixed with a top plate, a bearing plate is provided above the top plate, the bearing plate is provided with a plurality of vertical force transferring rods, the force transferring rods vertically penetrate through the top plate and sliding fit with the top plate, lower ends of the force transferring rods are provided with a tensile base, a top of the tensile base is provided with a lower clamp holder, a bottom of the top plate is provided with an upper clamp holder, and a clamp center of the upper clamp holder overlaps with a clamp center of the lower clamp holder. An acoustic component and a seepage component are provided in the upper clamp holder and the lower clamp holder.

Abstract: An integrated acoustic detection and rock direct tensile test machine includes a support frame. A top of the support frame is provided with a top plate and a bearing plate is provided above the top plate. The bearing plate is provided with force transferring rods, lower ends of which are provided with a tensile base. A top of the tensile base is provided with a lower clamp holder and a bottom of the top plate is provided with an upper clamp holder. An upper channel is provided inside the upper clamp holder. The upper channel is provided with an acoustic transmitting probe. A lower channel is provided inside the lower clamp holder. One end of the lower channel is communicated with the outside, the other end is provided with an acoustic receiving probe. The lower channel extends to a bottom of a clamping chamber of the lower clamp holder.

Abstract: This invention relates to an insect detection device comprising a sensing device. The sensing device comprises an optical source configured to emit an optical beam; a first lens group configured to collimate the optical beam to form a beam width of a first predetermined range and a beam height of a second predetermined range; a second lens group configured to collect the optical beam from the first lens group and arranged apart from the first lens group defining a sensing zone; an optical detector configured to receive the beam from the second lens group and translate the beam to electrical signals; and a processing unit configured to switch on the optical source and receive the electrical signals from the optical detector.

Abstract: The invention relates to methods and compositions for detecting colorectal cancer and colorectal polyps by measurement of metabolites in bodily fluids such as urine, including diacetylspermine and kynurenine.

Abstract: A larvae counter comprising a first container for receiving water, eggs of insects and/or larvae, a second container in fluid communication with the first container for receiving water and larvae from the first container, and a larvae counting module in fluid communication with the second container for receiving water and larvae from the second container and counting the larvae.

Abstract: A larvae counter comprising a first container for receiving water, eggs of insects and/or larvae, a second container in fluid communication with the first container for receiving water and larvae from the first container, and a larvae counting module in fluid communication with the second container for receiving water and larvae from the second container and counting the larvae.

Abstract: This invention relates to an insect detection device comprising a sensing device. The sensing device comprises an optical source configured to emit an optical beam; a first lens group configured to collimate the optical beam to form a beam width of a first predetermined range and a beam height of a second predetermined range; a second lens group configured to collect the optical beam N from the first lens group and arranged apart from the first lens group defining a sensing zone; an optical detector configured to receive the beam from the second lens group and translate the beam to electrical signals; and a processing unit configured to switch on the optical source and receive the electrical signals from the optical detector.

Abstract: The invention relates to methods and compositions for detecting colorectal cancer and colorectal polyps by measurement of metabolites in bodily fluids such as urine, including diacetylspermine and kynurenine.

Abstract: According to an aspect, a method comprises maintaining, by a cache control unit in a first packet data network, white and black lists of data servers in a second packet data network that are allowed or unable to use a cache server in the first packet data network, respectively; monitoring data traffic to and from data servers in the second packet data network over an interface between the first and second packet data network; comparing the candidate data servers to the data servers in the white and black lists; and in response to a candidate data server being in neither list, performing the following: causing sending a cache request to the candidate data server and in response to receiving an acknowledgement to the cache request within a pre-defined time, adding the candidate data server to the white list, otherwise adding the candidate data server to the black list.

Abstract: According to an aspect, a method comprises maintaining, by a cache control unit in a first packet data network, white and black lists of data servers in a second packet data network that are allowed or unable to use a cache server in the first packet data network, respectively; monitoring data traffic to and from data servers in the second packet data network over an interface between the first and second packet data network; comparing the candidate data servers to the data servers in the white and black lists; and in response to a candidate data server being in neither list, performing the following: causing sending a cache request to the candidate data server and in response to receiving an acknowledgement to the cache request within a pre-defined time, adding the candidate data server to the white list, otherwise adding the candidate data server to the black list.

Abstract: A larvae counter comprising a first container for receiving water, eggs of insects and/or larvae, a second container in fluid communication with the first container for receiving water and larvae from the first container, and a larvae counting module in fluid communication with the second container for receiving water and larvae from the second container and counting the larvae.

Abstract: Particular embodiments described herein provide for an electronic device that can be configured to receive data related to execution of a sandboxed process, determine if a high privileged process was created by the sandboxed process, and block the sandboxed process from executing if the high privileged process was created by the sandboxed process and the data indicates the sandboxed process is attempting a sandbox bypass attack. In an example, the high privileged process was created by the sandboxed process if a resource folder is associated with a sandbox folder. In another example, the high privileged process was created by the sandboxed process if a resource folder was created by a broker process in response to a request by the sandboxed process.

Abstract: Particular embodiments described herein provide for an electronic device that can be configured to identify regions of code to be monitored, probe and lock code pages that include the identified regions of code, and remap the code pages as execute only. The code pages can be remapped as execute only in an alternate extended page table view.