Patents by Inventor Lu-Shiun Her

Lu-Shiun Her has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibition of nucleocytoplasmic transport by vesicular stomatitis virus M protein-like polypeptides
    Patent number: 6653103
    Abstract: A fragment of vesicular stomatitis virus (VSV) matrix protein (M protein) and M proteins of other viral species that can inhibit nucleocytoplasmic transport of RNA, proteins and RNA-protein complexes are disclosed. These polypeptide products and related polypeptides can be used to inhibit nucleocytoplasmic transport. Further disclosed are fragments of the VSV M protein that can enter into the nucleus of a cell. These fragments and the full length of the VSV M protein can be used to introduce other polypeptides into the nucleus of a cell.
    Type: Grant
    Filed: March 29, 2002
    Date of Patent: November 25, 2003
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Jeannine M. Petersen, Lu-Shiun Her, James E. Dahlberg, Doreen R. Glodowski
  • Inhibition of nucleocytoplasmic transport by vesicular stomatitis virus M protein-like polypeptides
    Publication number: 20030086942
    Abstract: A fragment of vesicular stomatitis virus (VSV) matrix protein (M protein) and M proteins of other viral species that can inhibit nucleocytoplasmic transport of RNA, proteins and RNA-protein complexes are disclosed. These polypeptide products and related polypeptides can be used to inhibit nucleocytoplasmic transport. Further disclosed are fragments of the VSV M protein that can enter into the nucleus of a cell. These fragments and the full length of the VSV M protein can be used to introduce other polypeptides into the nucleus of a cell.
    Type: Application
    Filed: March 29, 2002
    Publication date: May 8, 2003
    Inventors: Jeannine M. Petersen, Lu-Shiun Her, James E. Dahlberg, Doreen R. Glodowski
  • Method of inhibition of nucleo-cytoplasmic transport by M protein of vesicular stomatitis virus
    Patent number: 5888727
    Abstract: A method of inhibiting transport of nucleic acids between the nucleus and cytoplasm of a cell is disclosed. In one embodiment, this method comprises the step of exposing a cell to a sufficient amount of vesicular stomatitis virus M protein such that the transport of RNA and protein through the nuclear envelope of the cell is impeded. A chimeric RNA capable of nuclear export is also disclosed.
    Type: Grant
    Filed: May 21, 1997
    Date of Patent: March 30, 1999
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Elsebet Lund, James E. Dahlberg, Lu-Shiun Her, Yan Cheng, Christian Grimm