Abstract: A solid oral dosage form comprising therapeutically effective amounts of acetaminophen and a non-steroidal anti-inflammatory drug (NSAID) as active ingredients. The dosage form may contain binder material to cohesively bind the ingredients. The dosage form may further comprise a disintegrant to ensure effective disintegration in the gastrointestinal tract. For example, the solid oral dosage form may be a single tablet that contains about 1,000 mg of acetaminophen and about 400 mg of ibuprofen. In another example, the solid oral dosage form may be a single tablet that contains about 650 mg of acetaminophen and about 400 mg of ibuprofen. This invention may be particularly suitable in the management of dental pain.