Patents by Inventor Luc Agnes Louis Jean Bosco Regniers

Luc Agnes Louis Jean Bosco Regniers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant nucleic acid sequences and methods for determining both genotoxicity and mutagenicity of a sample and the kinetics of the genotoxicity
    Patent number: 6602666
    Abstract: A recombinant nucleic acid sequence comprising an SOS regulated promoter with an induction ratio higher than 40, said promoter being operatively linked to a reporter encoding nucleic acid sequence encoding a reporter resulting in a signal that can be assayed as light production. A biosensor comprising such a nucleic acid sequence and methods for determining genotoxicity and the presence of multiple genotoxic compounds using such a biosensor are disclosed.
    Type: Grant
    Filed: April 25, 2001
    Date of Patent: August 5, 2003
    Assignee: Vlaamse Instelling Technologisch Onderzoek (V.I.T.O.)
    Inventors: Daniel Van Der Lelie, Brigitte Marie Francoise Borremans, Ann Irma Alice Provoost, Luc Agnes Louis Jean Bosco Regniers, Luc Philipinne Edouard Verschaeve
  • Recombinant nucleic acid sequences and methods for determining both genotoxicity and mutagenicity of a sample and the kinetics of the genotoxicity
    Patent number: 6521751
    Abstract: A recombinant nucleic acid sequence comprising an SOS regulated promoter with an induction ratio higher than 40, said promoter being operatively linked to a reporter encoding nucleic acid sequence encoding a reporter resulting in a signal that can be assayed as light production. A biosensor compromising such a nucleic acid sequence and methods for determining genotoxicity and the presence of multiple genotoxic compounds using such a biosensor are disclosed.
    Type: Grant
    Filed: December 2, 1998
    Date of Patent: February 18, 2003
    Assignee: Vlaamse Instelling voor Technologisch Onderzoek (VITO)
    Inventors: Daniel Van Der Lelie, Brigitte Marie Francoise Borremans, Ann Irma Alice Provoost, Luc Agnes Louis Jean Bosco Regniers, Luc Philipinne Edouard Verschaeve
  • Recombinant nucleic acid sequences and methods for determining both genotoxicity and mutagenicity of a sample and the kinetics of the genotoxicity
    Publication number: 20030003578
    Abstract: A recombinant nucleic acid sequence comprising an SOS regulated promoter with an induction ratio higher than 40, said promoter being operatively linked to a reporter encoding nucleic acid sequence encoding a reporter resulting in a signal that can be assayed as light production. A biosensor comprising such a nucleic acid sequence and methods for determining genotoxicity and the presence of multiple genotoxic compounds using such a biosensor are disclosed.
    Type: Application
    Filed: April 25, 2001
    Publication date: January 2, 2003
    Applicant: Vlaamse Instelling Technologisch Onderzoek
    Inventors: Daniel Van Der Lelie, Brigitte Marie Francoise Borremans, Ann Irma Alice Provoost, Luc Agnes Louis Jean Bosco Regniers, Luc Philipinne Edouard Verschaeve
  • Diagnostic systems and method for determining the presence of a genotoxic and/or toxic compound in a sample
    Patent number: 6472152
    Abstract: This invention concerns a diagnostic system made of: a transformed microorganism capable of an increased reporter activity upon exposure to an environmental insult, said microorganism having a stress inducible promoter sequence being operatively linked to a reported encoding nucleic acid sequence encoding a reporter molecule resulting in a signal that can be assayed, and of a transformed microorganism having a constitutive and non stress inducible promoter sequence being operatively linked to a reporter encoding nucleic acid sequence encoding a reporter molecule resulting in a signal that can be assayed.
    Type: Grant
    Filed: January 27, 2000
    Date of Patent: October 29, 2002
    Assignee: Vlaamse Instelling Voor Technologish Onderzoek (VITO)
    Inventors: Daniel Van Der Lelie, Luc Agnes Louis Jean Bosco Regniers, Safiyh Taghavi, Philippe Gilbert Ghislain Corbisier, Luc Philippine Edouard Verschaeve