Abstract: A system for measuring (200) a sample (2) by deflectometry comprising: a source (10) for generating a light beam in a source plane (105); an illumination module (19) for forming an illumination beam (9) comprising: a first converging optical element (18); a first selection optical element (16) with a first aperture (160); reflective matrix optical modulation means (30) to form a pattern (7), said first aperture (160) being configured to control the angles of said illumination beam (9) on said reflective matrix optical modulation means (30); a Schlieren lens (20) for obtaining an angle-intensity encoding of said pattern (7) on the sample (2); imaging (40) and detecting means (50) for detecting an image of said sample (2).

Abstract: A method of performing a plurality of synthesis processes of preparing a radiopharmaceutical in series, which method includes carrying out a first synthesis run comprising the steps of: a) providing water containing 18F; b) trapping the 18F from the water provided in step a) on an anion exchange material; c) eluting the trapped 18F from the anion exchange material to a reaction vessel of first radiopharmaceutical synthesis cassette; d) preparing a radiopharmaceutical incorporating the eluted 18F using the first radiopharmaceutical synthesis cassette; where steps a)-d) are repeated in at least one subsequent run using another radiopharmaceutical synthesis cassette; and where the method includes a reconditioning step of treating the anion exchange material with water between two consecutive runs. Other aspects of the invention relate to a device for performing this method, and a cassette for use in the device.

Abstract: A cassette for performing a plurality of synthesis processes of preparing a radiopharmaceutical in series in a synthesizer, includes: at least one manifold provided with a plurality of valves connectable to and operable by the synthesizer; an anion-exchanger comprising an anionic exchange material; an eluent container comprising an eluent; and a recondition container comprising a reconditioning agent.

Abstract: Method for connecting, in a fluid manner, a system (100) for fluid communication comprising a first (10) and a second (20) fluid valve and comprising the following steps:—providing a first (10) and a second (20) fluid valve, —providing a first pipe (60), —inserting each of the ends (61, 62) of the first pipe (60) into each of the fluid valves (10, 20) in order to form a fluid assembly (100), —providing a compression means (1) comprising two ends (2, 3), —positioning said two ends (2, 3) of said compression means (1) on either side of said fluid assembly (100), —applying a compression force onto said fluid assembly (100) via the compression means (1).

Abstract: Method for connecting, in a fluid manner, a system (100) for fluid communication comprising a first (10) and a second (20) fluid valve and comprising the following steps:—providing a first (10) and a second (20) fluid valve,—providing a first pipe (60),—inserting each of the ends (61, 62) of the first pipe (60) into each of the fluid valves (10, 20) in order to form a fluid assembly (100),—providing a compression means (1) comprising two ends (2, 3),—positioning said two ends (2, 3) of said compression means (1) on either side of said fluid assembly (100),—applying a compression force onto said fluid assembly (100) via the compression means (1).

Abstract: A cassette for performing a plurality of synthesis processes of preparing a radiopharmaceutical in series in a synthesizer, includes: at least one manifold provided with a plurality of valves connectable to and operable by the synthesizer; an anion-exchanger comprising an anionic exchange material; an eluent container comprising an eluent; and a recondition container comprising a reconditioning agent.

Abstract: A method of performing a plurality of synthesis processes of preparing a radiopharmaceutical in series includes carrying out a first synthesis run including the steps of: a) providing water containing fluorine-18; b) trapping the fluorine-18 from the water provided in step a) on an anion exchange material; c) eluting the trapped fluorine-18 from the anion exchange material to a reaction vessel of first radiopharmaceutical synthesis cassette; d) preparing a radiopharmaceutical incorporating the eluted fluorine-18 using the first radiopharmaceutical synthesis cassette; where steps a)-d) are repeated in at least one subsequent run using another radiopharmaceutical synthesis cassette; and where the method includes a reconditioning step of the anion exchange material between two consecutive runs. A device for performing this method and a cassette for use in the device are also disclosed.

Abstract: A method of performing a plurality of synthesis processes of preparing a radiopharmaceutical in series includes carrying out a first synthesis run including the steps of: a) providing water containing fluorine-18; b) trapping the fluorine-18 from the water provided in step a) on an anion exchange material; c) eluting the trapped fluorine-18 from the anion exchange material to a reaction vessel of first radiopharmaceutical synthesis cassette; d) preparing a radiopharmaceutical incorporating the eluted fluorine-18 using the first radiopharmaceutical synthesis cassette; where steps a)-d) are repeated in at least one subsequent run using another radiopharmaceutical synthesis cassette; and where the method includes a reconditioning step of the anion exchange material between two consecutive runs. A device for performing this method and a cassette for use in the device are also disclosed.

Abstract: The invention relates to a compressed-air device for controlling valves comprising, in a longitudinal direction, a first vane-type rotary cylinder (1) having a front face (2) as well as a back face (4), said front face (2) being provided with a rotatable head (3), and a second vane-type rotary cylinder (10) having a front face (11) and a back face, said first (1) and second (10) cylinders each being supplied with compressed air by means of a compressed air valve connected to two ports (7, 8; 14, 15) on each of said first and second cylinders.

Abstract: The invention relates to a compressed-air device for controlling valves comprising, in a longitudinal direction, a first vane-type rotary cylinder (1) having a front face (2) as well as a back face (4), said front face (2) being provided with a rotatable head (3), and a second vane-type rotary cylinder (10) having a front face (11) and a back face, said first (1) and second (10) cylinders each being supplied with compressed air by means of a compressed air valve connected to two ports (7, 8; 14, 15) on each of said first and second cylinders.

Abstract: In one embodiment, an apparatus includes an interface and a queue generator. The interface obtains a plurality of submissions associated with a conference call. The submissions include at least one text-based submission and at least one audio-based submission. The queue generator manages a queue that has representations of at least some of the submissions, and is accessible to a speaker associated with the conference call. The representations include a first representation of the text-based submission and a second representation of the audio-based submission.

Abstract: Disclosed are processes for resolving chiral (2S) and (2R) benzopyrans, racemizing benzopyrans, and recycling racemized benzopyrans to increase yield of a desired enantiomer to provide purified or substantially purified bicyclic amino substituted benzopyran derivatives. Such benzopyran derivatives are preferably chromans which can be coupled with benzoyl derivatives via an amide bond to produce potent platelet aggregation inhibitors.

Abstract: Disclosed are processes for producing benzopyran compounds, reduced 2-(chroman-2-yl) acetic acid compounds and 2-(6-aminochroman-2-yl)acetic acid esters which are intermediates for producing platelet aggregation inhibitors and/or are themselves potent platelet aggregation inhibitors.