Patents by Inventor Luc Cynober

Luc Cynober has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11957652
    Abstract: Compositions contain citrulline and leucine or a metabolite thereof, such as hydroxyisocaproic acid (HICA) or beta-hydroxy-beta-methylbutyrate (HMB), including, for example, a synergistic amount of citrulline and leucine. Such compositions may be used in methods for treatment of pre-diabetes, metabolic syndrome, or diabetes.
    Type: Grant
    Filed: July 22, 2022
    Date of Patent: April 16, 2024
    Assignee: Societe des Produits Nestle S.A.
    Inventors: Christophe Moinard, Gabrielle Ventura, Denis Breuille, Christian Darimont-Nicolau, Luc Cynober
  • Publication number: 20220354814
    Abstract: Compositions contain citrulline and leucine or a metabolite thereof, such as hydroxyisocaproic acid (HICA) or beta-hydroxy-beta-methylbutyrate (HMB), including, for example, a synergistic amount of citrulline and leucine. Such compositions may be used in methods for treatment of pre-diabetes, metabolic syndrome, or diabetes.
    Type: Application
    Filed: July 22, 2022
    Publication date: November 10, 2022
    Inventors: Christophe Moinard, Gabrielle Ventura, Denis Breuille, Christian Darimont-Nicolau, Luc Cynober
  • Patent number: 11419838
    Abstract: Compositions contain citrulline and leucine or a metabolite thereof including, for example, a synergistic amount of citrulline and leucine. Such compositions may be used in methods for the treatment of pre-diabetes, metabolic syndrome, hyperglycemia, or diabetes.
    Type: Grant
    Filed: February 8, 2018
    Date of Patent: August 23, 2022
    Assignee: Societe des Produits Nestle S.A.
    Inventors: Christophe Moinard, Gabrielle Ventura, Denis Breuille, Christian Darimont-Nicolau, Luc Cynober
  • Publication number: 20180338942
    Abstract: Compositions contain citrulline and leucine or a metabolite thereof including, for example, a synergistic amount of citrulline and leucine. Such compositions may be used in methods for the treatment of pre-diabetes, metabolic syndrome, hyperglycemia, or diabetes.
    Type: Application
    Filed: February 8, 2018
    Publication date: November 29, 2018
    Inventors: Christophe Moinard, Gabrielle Ventura, Denis Breuille, Christian Darimont-Nicolau, Luc Cynober
  • Patent number: 9913818
    Abstract: The present disclosure relates generally to compositions that comprise citrulline and leucine or a metabolite thereof including, for example, a synergistic amount of citrulline and leucine. Such compositions may be used in methods for the treatment of metabolic syndrome, hyperglycemia, and/or hyperinsulinemia.
    Type: Grant
    Filed: October 3, 2014
    Date of Patent: March 13, 2018
    Assignee: Nestec S.A.
    Inventors: Christophe Moinard, Gabrielle Ventura, Denis Breuille, Christian Darimont-Nicolau, Luc Cynober
  • Publication number: 20170340587
    Abstract: The present invention relates to the field of food supplement and medicament supporting muscle metabolism, more precisely muscle protein synthesis. In particular, the invention relates to a composition comprising N-carbamoylputrescine (NCP). The invention further relates to the non-therapeutic use of N-carbamoylputrescine (NCP) to enhance muscle protein synthesis in a subject. Moreover, the invention also relates to N-carbamoylputrescine for its use as a medicament.
    Type: Application
    Filed: November 23, 2016
    Publication date: November 30, 2017
    Inventors: Jean-Pascal DE BANDT, Luc CYNOBER, David RAMANI, Christiane GARBAY
  • Patent number: 9533946
    Abstract: The present invention relates to the field of food supplement and medicament supporting muscle metabolism, more precisely muscle protein synthesis. In particular, the invention relates to a composition comprising N-carbamoylputrescine (NCP). The invention further relates to the non-therapeutic use of N-carbamoylputrescine (NCP) to enhance muscle protein synthesis in a subject. Moreover, the invention also relates to N-carbamoylputrescine for its use as a medicament.
    Type: Grant
    Filed: May 25, 2016
    Date of Patent: January 3, 2017
    Assignee: CITRAGE
    Inventors: Jean-Pascal De Bandt, Luc Cynober, David Ramani, Christiane Garbay
  • Publication number: 20160235699
    Abstract: The present disclosure relates generally to compositions that comprise citrulline and leucine or a metabolite thereof including, for example, a synergistic amount of citrulline and leucine. Such compositions may be used in methods for the treatment of metabolic syndrome, hyperglycemia, and/or hyperinsulinemia.
    Type: Application
    Filed: October 3, 2014
    Publication date: August 18, 2016
    Inventors: Christophe Moinard, Gabrielle Ventura, Denis Breuille, Christian Darimont-Nicolau, Luc Cynober
  • Publication number: 20150017203
    Abstract: A combination product includes as active substances, at least an inhibitor of the HMG-CoA-reductase enzyme and citrulline, or a bioequivalent compound thereof, for treating excess weight or obesity and/or the accumulation of body fat. A cosmetic treatment method for improving or slimming the figure and/or for stimulating the loss of excess weight and/or of cellulite and/or for limiting the accumulation thereof, includes the administration of a combination product including as active substances, at least an inhibitor of the HMG-CoA-reductase enzyme or a physiologically acceptable salt thereof, and citrulline, or a bioequivalent compound thereof, or one of theirs analogues, and the renewal of the administration until the expected cosmetic effect is obtained. The combination product such as previously defined for improving or slimming the figure and/or for stimulating the loss of excess weight and/or of cellulite and/or for limiting the accumulation thereof is also described.
    Type: Application
    Filed: February 28, 2013
    Publication date: January 15, 2015
    Applicants: UNIVERSITE PARIS DESCARTES, ASSISTANCE PUBLIQUE HOPITAUX DE PARIS, INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - INRA
    Inventors: Beatrice Morio-Liondore, Frederic Capel, Jean-Pascal De Bandt, Christophe Moinard, Luc Cynober
  • Publication number: 20140018424
    Abstract: L-citrulline or a nutraceutically or pharmaceutically acceptable salt thereof for reducing the kinetics of tumour development or reduce the incidence of tumours in aged humans and animals.
    Type: Application
    Filed: January 10, 2012
    Publication date: January 16, 2014
    Applicant: UNIVERSITE PARIS DESCARTES
    Inventors: Christophe Moinard, Servane Le Plenier, Agathe Raynaud-Simon, Vickie Baracos, Luc Cynober
  • Publication number: 20130296234
    Abstract: The present invention provides methods of providing long-term and tube-fed nutrition to patients requiring same. More specifically, the present invention provides methods and compositions for providing long-term nutrition to an elderly patient.
    Type: Application
    Filed: June 10, 2013
    Publication date: November 7, 2013
    Inventors: Herve Le-Henand, Francois Murbach, Michael Jedwab, Claudia Roessle, Luc Cynober, Agathe Raynaud-Simon
  • Patent number: 8409592
    Abstract: The present invention generally relates to the field of nutrition and health. In particular, the present invention provides a composition that can be used to maintain or improve thymus health. One embodiment of the present invention is the use of whey or at least one protein fraction thereof for the preparation of a composition to maintain or improve thymus function.
    Type: Grant
    Filed: September 14, 2009
    Date of Patent: April 2, 2013
    Assignee: Nestec S.A.
    Inventors: Karine Vidal, Eric Delpierre, Cecile Loi, Christophe Moinard, Christine Charrueau, Denis Breuille, Luc Cynober
  • Publication number: 20120039944
    Abstract: The present invention generally relates to the field of nutrition and health. In particular, the present invention provides a composition that can be used to maintain or improve thymus health. One embodiment of the present invention is the use of whey or at least one protein fraction thereof for the preparation of a composition to maintain or improve thymus function.
    Type: Application
    Filed: September 14, 2009
    Publication date: February 16, 2012
    Applicant: NESTEC S.A.
    Inventors: Karine Vidal, Eric Delpierre, Cecile Loi, Christophe Moinard, Christine Charrueau, Denis Breuille, Luc Cynober
  • Publication number: 20110201128
    Abstract: The present invention relates to a method for detecting bowel transplant rejection. The detection method according to the invention is a method for the in vitro detection of bowel transplant rejection comprising steps for measuring the concentration at markers in a fluid sample, calculating the difference for each marker with a reference concentration, comparing for each marker the difference with a discriminatory threshold variation and assigning a score. The present invention is particularly applicable in the medical field, more specifically in the field of transplantations and transplant rejection detection.
    Type: Application
    Filed: November 27, 2008
    Publication date: August 18, 2011
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE- CNRS
    Inventors: Thierry Yandza, Nathalie Neveux, Luc Cynober
  • Publication number: 20100298437
    Abstract: The invention relates to the use of L-citrulline (I) or of one of its pharmaceutically acceptable salts in the preparation of a drug for the treatment of states or undernutrition as linked to a lowering of protein synthesis within the framework of pathologies which do not result from an intestinal insufficiency.
    Type: Application
    Filed: August 29, 2007
    Publication date: November 25, 2010
    Applicants: UNIVERSITE RENE DESCARTES-PARIS 5, BIOCODEX
    Inventors: Christophe Moinard, Marion Jourdan, Stephane Walrand, Luc Cynober
  • Publication number: 20100093863
    Abstract: A method of using L-citrulline of the formula (I) for preparing a cosmetic composition, a food or nutraceutic composition or a pharmaceutical composition for treating diseases related to an increase in protein carbonylation, in particular for treating neurodegenerative diseases such as Alzheimer's or Parkinson's disease.
    Type: Application
    Filed: March 20, 2008
    Publication date: April 15, 2010
    Applicants: UNIVERSITE PARIS DESCARTESURE, INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE, ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS, UNIVERSITE D' AUVERGNE
    Inventors: Christophe Moinard, Stephane Walrand, Yves Boirie, Luc Cynober
  • Publication number: 20100094246
    Abstract: The present invention provides methods of providing long-term and tube-fed nutrition to patients requiring same. More specifically, the present invention provides methods and compositions for providing long-term nutrition to an elderly patient.
    Type: Application
    Filed: October 17, 2007
    Publication date: April 15, 2010
    Inventors: Herve Le-Henand, François Murbach, Michael Jedwab, Claudia Roessle, Luc Cynober, Agathe Raynaud-Simon
  • Publication number: 20100055197
    Abstract: The present invention provides methods and compositions for providing long-term tube-fed nutrition. More specifically, the present invention provides methods and compositions for providing long-term tube-fed maintenance to a patient.
    Type: Application
    Filed: October 17, 2007
    Publication date: March 4, 2010
    Inventors: Hervé Le-Henand, Francois Murbach, Michael Jedwab, Claudia Roessle, Luc Cynober, Burde Alain, Herbert Lochs
  • Publication number: 20080312263
    Abstract: The present invention relates to the use, of at least one statin, or of a pharmaceutically acceptable salt thereof, in combination with at least one compound of the following formula (I): in which R represents, —H, or a pharmaceutically acceptable salt thereof, for the preparation of a medicament intended for the prevention or treatment of atherosclerosis, in particular of primary or secondary atherosclerosis, hypertension, diabetes, or neurodegenerative diseases, in particular Alzheimer's disease.
    Type: Application
    Filed: July 14, 2008
    Publication date: December 18, 2008
    Applicant: UNIVERSITE RENE DESCARTES-PARIS 5
    Inventors: REMY COUDERC, Carole Rasmusen, Chantal Martin, Viviane Tricottei, Luc Cynober, Christophe Moinard
  • Publication number: 20070219225
    Abstract: The present invention relates to the use, of at least one statin, or of a pharmaceutically acceptable salt thereof, in combination with at least one compound of the following formula (I): in which R represents, —H, or a pharmaceutically acceptable salt thereof, for the preparation of a medicament intended for the prevention or treatment of atherosclerosis, in particular of primary or secondary atherosclerosis, hypertension, diabetes, or neurodegenerative diseases, in particular Alzheimer's disease.
    Type: Application
    Filed: April 29, 2005
    Publication date: September 20, 2007
    Applicant: UNIVERSITE RENE DESCARTES-PARIS 5
    Inventors: Remy Couderc, Carole Rasmusen, Chantal Martin, Viviane Tricottet, Luc Cynober, Christophe Moinard