Patents by Inventor Luc Grondard

Luc Grondard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and intermediates for the preparation of derivatives of N-(1-benzhydrylazetidin-3-yl)-N-phenylmethylsulfonamide
    Patent number: 8071788
    Abstract: The invention relates to a novel method for the synthesis of N-{1-[bis(4-chlorophenyl)methyl]azetidin-3-yl}-N-(3,5 -difluorophenyl)methylsulfonamide.
    Type: Grant
    Filed: December 11, 2009
    Date of Patent: December 6, 2011
    Assignee: Sanofi-Aventis
    Inventors: Philippe Boffelli, Michel Delthil, Luc Grondard, Maxime Lampilas, Joel Malpart, Stephane Mutti, Lahlou Nait-Bouda, Joerg Reike-Zapp
  • Mixtures of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
    Patent number: 8071570
    Abstract: The present invention relates to mixtures of polysaccharides derived from heparin having a mean molecular weight of 1500 to 3000 Daltons and an anti-Xa/anti-IIa ratio greater than 30, their method of preparation and pharmaceutical compositions containing them.
    Type: Grant
    Filed: May 9, 2011
    Date of Patent: December 6, 2011
    Assignee: Aventis Pharma S.A.
    Inventors: Christian Viskov, Vesna Biberovic, Pierre Mourier, Luc Grondard
  • MIXTURES OF POLYSACCHARIDES DERIVED FROM HEPARIN, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
    Publication number: 20110212915
    Abstract: The present invention relates to mixtures of polysaccharides derived from heparin having a mean molecular weight of 1500 to 3000 Daltons and an anti-Xa/anti-IIa ratio greater than 30, their method of preparation and pharmaceutical compositions containing them.
    Type: Application
    Filed: May 11, 2011
    Publication date: September 1, 2011
    Applicant: AVENTIS PHARMA S.A.
    Inventors: Vesna Biberovic, Luc Grondard, Pierre Mourier, Christian VISKOV
  • Mixtures of sulfated oligosaccharides
    Patent number: 8003623
    Abstract: The present invention relates to mixtures of polysaccharides derived from heparin having a mean molecular weight of 1500 to 3000 Daltons and an anti-Xa/anti-IIa ratio greater than 30, their method of preparation and pharmaceutical compositions containing them.
    Type: Grant
    Filed: August 2, 2007
    Date of Patent: August 23, 2011
    Assignee: Aventis Pharma S.A.
    Inventors: Vesna Biberovic, Luc Grondard, Pierre Mourier, Christian Viskov
  • MIXTURES OF POLYSACCHARIDES DERIVED FROM HEPARIN, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
    Publication number: 20110201573
    Abstract: The present invention relates to mixtures of polysaccharides derived from heparin having a mean molecular weight of 1500 to 3000 Daltons and an anti-Xa/anti-IIa ratio greater than 30, their method of preparation and pharmaceutical compositions containing them.
    Type: Application
    Filed: May 9, 2011
    Publication date: August 18, 2011
    Applicant: AVENTIS PHARMA S.A.
    Inventors: Vesna Biberovic, Luc Grondard, Pierre Mourier, Christian VISKOV
  • METHOD AND INTERMEDIATES FOR THE PREPARATION OF DERIVATIVES OF N (1-BENZHYDRYLAZETIDIN-3-YL)-N-PHENYLMETHYLSULFONAMIDE
    Publication number: 20100087414
    Abstract: The invention relates to a novel method for the synthesis of N-{1-[bis(4-chlorophenyl)methyl]azetidin-3-yl}-N-(3,5 -difluorophenyl)methylsulfonamide.
    Type: Application
    Filed: December 11, 2009
    Publication date: April 8, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Philippe BOFFELLI, Michel DELTHIL, Luc GRONDARD, Maxime LAMPILAS, Joel MALPART, Stephane MUTTI, Lahlou NAIT-BOUDA, Joerg RIEKE-ZAPP
  • Product, method and intermediates for the preparation of azetidine derivatives
    Patent number: 7687493
    Abstract: The present invention relates to a novel method for the preparation of azetidine derivatives such as N-{1-[bis(4-chlorophenyl)methyl]azetidin-3-yl}-N-quinol-6-ylmethylsulfonamide and the dihydrochloride thereof and N-{1-[bis(4-chlorophenyl)methyl]azetidin-3-yl}-N-(3,5-difluorophenyl)methylsulfonamide.
    Type: Grant
    Filed: March 22, 2007
    Date of Patent: March 30, 2010
    Assignee: Aventis Pharma SA
    Inventors: Stephane Mutti, Michel Lavigne, Luc Grondard, Joel Malpart, Joerg Rieke-Zapp, Veronique Crocq-Stuerga
  • Method and intermediates for the preparation of derivatives of N (1-benzhydrylazetidin-3-yl)-N-phenylmethylsulfonamide
    Patent number: 7652154
    Abstract: The invention relates to a novel method for the synthesis of N-{1-[bis(4-chlorophenyl)methyl]azetidin-3-yl}-N-(3,5-difluorophenyl)methylsulfonamide.
    Type: Grant
    Filed: August 20, 2008
    Date of Patent: January 26, 2010
    Assignee: Sanofi-Aventis
    Inventors: Philippe Boffelli, Michel Delthil, Luc Grondard, Maxime Lampilas, Joel Malpart, Stephane Mutti, Lahlou Nait-Bouda, Joerg Reike-Zapp
  • METHOD AND INTERMEDIATES FOR THE PREPARATION OF DERIVATIVES OF N (1-BENZHYDRYLAZETIDIN-3-YL)-N-PHENYLMETHYLSULFONAMIDE
    Publication number: 20080312205
    Abstract: The invention relates to a novel method for the synthesis of N-{1-[bis(4-chlorophenyl)methyl]azetidin-3-yl}-N-(3,5-difluorophenyl)methylsulfonamide.
    Type: Application
    Filed: August 20, 2008
    Publication date: December 18, 2008
    Applicant: SANOFI-AVENTIS
    Inventors: Philippe BOFFELLI, Michel DELTHIL, Luc GRONDARD, Maxime LAMPILAS, Joel MALPART, Stephane MUTTI, Lahlou NAIT-BOUDA, Joerg RIEKE-ZAPP
  • Method and intermediates for the preparation of derivatives of N-(1-benzhydrylazetidin-3-yl)-N-phenylmethylsulfonamide
    Patent number: 7429668
    Abstract: The invention relates to a novel method for the synthesis of N-{1-[bis(4-chlorophenyl)methyl]azetidin-3-yl}-N-(3,5-difluorophenyl)methylsulfonamide.
    Type: Grant
    Filed: March 28, 2007
    Date of Patent: September 30, 2008
    Assignee: Sanofi-Aventis
    Inventors: Philippe Boffelli, Michel Delthil, Luc Grondard, Maxime Lampilas, Joel Malpart, Stephane Mutti, Lahlou Nait-Bouda, Joerg Rieke-Zapp
  • NOVEL PRODUCT, METHOD AND INTERMEDIATES FOR THE PREPARATION OF AZETIDINE DERIVATIVES
    Publication number: 20070270463
    Abstract: The present invention relates to a novel method for the preparation of azetidine derivatives such as N-{1-[bis(4-chlorophenyl)methyl]azetidin-3-yl}-N-quinol-6-ylmethylsulfonamide and the dihydrochloride thereof and N-{1-[bis(4-chlorophenyl)methyl]azetidin-3-yl}-N-(3,5-difluorophenyl)methylsulfonamide.
    Type: Application
    Filed: March 22, 2007
    Publication date: November 22, 2007
    Applicant: SANOFI-AVENTIS
    Inventors: Stephane Mutti, Michel Lavigne, Luc Grondard, Joel Malpart, Joerg Rieke-Zapp, Veronique Crocq-Stuerga
  • METHOD AND INTERMEDIATES FOR THE PREPARATION OF DERIVATIVES OF N (1-BENZHYDRYLAZETIDIN-3-YL)-N-PHENYLMETHYLSULFONAMIDE
    Publication number: 20070244084
    Abstract: The invention relates to a novel method for the synthesis of N-{1-[bis(4-chlorophenyl)methyl]azetidin-3-yl}-N-(3,5-difluorophenyl)methylsulfonamide.
    Type: Application
    Filed: March 28, 2007
    Publication date: October 18, 2007
    Applicant: AVENTIS PHARMA SA
    Inventors: Philippe Boffelli, Michel Delthil, Luc Grondard, Maxime Lampilas, Joel Malpart, Stephane Mutti, Lahlou Nait-Bouda, Joerg Rieke-Zapp
  • Steroespecific preparation of chiral 1-aryl- and 1-heteroaryl-2-substituted ethyl-2-amines
    Patent number: 6433172
    Abstract: This invention is directed to methods for stereospecifically preparing [(1-optionally substituted aryl)- or (1-optionally substituted heteroaryl)]-2-substituted ethyl-2-amines, having chirality at the 2-position, and to intermediates to the substituted ethyl-2-amines.
    Type: Grant
    Filed: October 25, 1999
    Date of Patent: August 13, 2002
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: Luc Grondard, Jean-Paul Casimir, Patrick Leon, Michael K. O'Brien, Matthew R. Powers, Daniel Robin
  • Process for preparing N6-substituted adenosine derivatives
    Patent number: 6429315
    Abstract: This invention is directed to a process for preparing N6-substituted adenosine derivatives, to intermediates useful therefor and to methods of preparing these intermediates.
    Type: Grant
    Filed: January 21, 2000
    Date of Patent: August 6, 2002
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: Adam W. Sledeski, Luc Grondard, Matthew R. Powers, Tory H. Powner, Michael K. O'Brien, Ching T. Tsuei, Patrick Leon, Gregory G. Kubiak, Laurence Pailleres-Hubert, Benoit Viguier
  • Stereospecific preparation of chiral 1-aryl-and 1-heteroaryl-2-substituted ethyl-2-amines
    Patent number: 6127550
    Abstract: This invention is directed to methods for stereospecifically preparing [(1-optionally substituted aryl)- or (1-optionally substituted heteroaryl)]-2-substituted ethyl-2-amines, having chirality at the 2-position, and to intermediates to the substituted ethyl-2-amines.
    Type: Grant
    Filed: March 11, 1999
    Date of Patent: October 3, 2000
    Assignee: Rhone-Poulenc Rorer Pharmaceuticals Inc.
    Inventors: Luc Grondard, Jean-Paul Casimir, Patrick Leon, Michael K. O'Brien, Matthew R. Powers, Daniel Robin
  • Method for preparing streptogramins
    Patent number: 5789537
    Abstract: A method for preparing streptogramins of the formula (I): ##STR1## wherein R.sub.1 is methyl or ethyl, R.sub.2 is H and X and Y together form an oxo radical, or R.sub.1 is ethyl, R.sub.2 and X are H and Y is H or OH, or else R.sub.1 is ethyl, R.sub.2 is OH and X and Y together form an oxo radical, by demethylation of a synergistin derivative of the formula (II): ##STR2## wherein R.sub.1, R.sub.2, X and Y are as defined above, by means of a treatment with a periodate in an acetic medium, followed by a treatment in an aqueous medium.
    Type: Grant
    Filed: October 16, 1997
    Date of Patent: August 4, 1998
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Jean-Claude Barriere, Luc Grondard, Patrick Lefevre, Stephane Mutti