Patents by Inventor Luc Montagnier

Luc Montagnier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9029165
    Abstract: A method for detecting electromagnetic waves derived from bacterial DNA, comprising extracting and purifying nucleic acids from a sample; diluting the extracted purified nucleic acids in an aqueous solvent; measuring a low frequency electromagnetic emission over time from the diluted extracted purified nucleic acids in an aqueous solvent; performing a signal analysis of the low frequency electromagnetic emission over time; and producing an output, based on the signal analysis, in dependence on the DNA in the sample. The DNA may be extracted from at least one of blood, feces, urine, saliva, tears, seminal fluid, sweat, seminal and vaginal fluids of a patient, or water to determine, e.g., potability. The samples may be frozen. The extracting and purifying may comprise diluting the sample with an aqueous buffer and mixing; degrading proteins in the diluted sample; precipitating DNA from the buffer solution; and resuspending the precipitated DNA in an aqueous solution.
    Type: Grant
    Filed: May 9, 2014
    Date of Patent: May 12, 2015
    Inventor: Luc Montagnier
  • Patent number: 8736250
    Abstract: A method for detecting electromagnetic waves derived from bacterial DNA, comprising extracting and purifying nucleic acids from a sample; diluting the extracted purified nucleic acids in an aqueous solvent; measuring a low frequency electromagnetic emission over time from the diluted extracted purified nucleic acids in an aqueous solvent; performing a signal analysis of the low frequency electromagnetic emission over time; and producing an output, based on the signal analysis, in dependence on the DNA in the sample. The DNA may be extracted from at least one of blood, feces, urine, saliva, tears, seminal fluid, sweat, seminal and vaginal fluids of a patient, or water to determine, e.g., potability. The samples may be frozen. The extracting and purifying may comprise diluting the sample with an aqueous buffer and mixing; degrading proteins in the diluted sample; precipitating DNA from the buffer solution; and resuspending the precipitated DNA in an aqueous solution.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: May 27, 2014
    Inventor: Luc Montagnier
  • Publication number: 20130217000
    Abstract: A method for characterizing a biologically active biochemical element in a sample by prefiltering the sample and analyzing low frequency electromagnetic signals transmitted by the prefiltered solution. The prefiltering may be through a 150 nm or less filter. The prefiltering may be subsequent to a dilution, e.g., between 10?2 and 10?20 in water. The filtered sample may be stirred and/or centrifuged. During the analyzing, the solution may be excited using white noise. The analyzing may comprise comparing a signature with previously recorded signatures.
    Type: Application
    Filed: March 18, 2013
    Publication date: August 22, 2013
    Inventor: Luc Montagnier
  • Patent number: 8507196
    Abstract: This invention is in the field of lymphadenopathy virus. This invention relates to a diagnostic means and method to detect the presence of DNA, RNA, or antibodies of the lymphadenopathy retrovirus associated with the acquired immune deficiency syndrome or of the lymphadenopathy syndrome by the use of DNA fragments or the peptides encoded by said DNA fragments. The invention further relates to the DNA fragments, vectors comprising them, and the proteins expressed.
    Type: Grant
    Filed: April 23, 1993
    Date of Patent: August 13, 2013
    Assignees: Institut Pasteur, Centre National de la Recherche Scientifique
    Inventors: Marc Alizon, Francoise Barre Sinoussi, Pierre Sonigo, Pierre Tiollais, Jean-Claude Chermann, Luc Montagnier, Simon Wain-Hobson
  • Publication number: 20130196939
    Abstract: A method for identifying a risk factor for diseases, disorders or conditions, such as those caused by human immunodeficiency virus, using the polymerase chain reaction and specific primers. Methods for treating patients having these diseases, disorders or conditions by antimicrobial treatment of the risk factor by combined antiviral and antibacterial treatment or by sustaining or stimulating the subject's immune system. Methods for screening biological products including red blood cell preparations. Primers and methods for detecting nucleic acids or microbial agents associated with red blood cells, such as those associated with red blood cells in subjects infected with HIV and undergoing antiretroviral therapy.
    Type: Application
    Filed: January 28, 2013
    Publication date: August 1, 2013
    Inventor: Luc MONTAGNIER
  • Publication number: 20130143205
    Abstract: Methods for detecting polynucleotides, especially the DNA replicated from samples obtained from subjects infected with pathogenic viruses such as human immunodefiency virus, by detecting electromagnetic signals (“EMS”) emitted by such polynucleotides, and methods for improving the sensitivity of the polymerase chain reaction (“PCR”).
    Type: Application
    Filed: December 31, 2012
    Publication date: June 6, 2013
    Inventor: Luc MONTAGNIER
  • Patent number: 8405379
    Abstract: A method for detecting electromagnetic waves derived from bacterial DNA, comprising extracting and purifying nucleic acids from a sample; diluting the extracted purified nucleic acids in an aqueous solvent; measuring a low frequency electromagnetic emission over time from the diluted extracted purified nucleic acids in an aqueous solvent; performing a signal analysis of the low frequency electromagnetic emission over time; and producing an output, based on the signal analysis, in dependence on the DNA in the sample. The DNA may be extracted from at least one of blood, feces, urine, saliva, tears, seminal fluid, sweat, seminal and vaginal fluids of a patient, or water to determine, e.g., potability. The samples may be frozen. The extracting and purifying may comprise diluting the sample with an aqueous buffer and mixing; degrading proteins in the diluted sample; precipitating DNA from the buffer solution; and resuspending the precipitated DNA in an aqueous solution.
    Type: Grant
    Filed: September 16, 2009
    Date of Patent: March 26, 2013
    Inventor: Luc Montagnier
  • Patent number: 8329396
    Abstract: This invention is in the field of lymphadenopathy virus. This invention relates to a diagnostic means and method of detecting lymphadenopathy associated virus or related viruses or DNA pro-viruses with cloned DNA sequences which are hybridizable to genomic RNA and DNA of lymphadenopathy associated virus. It further relates to the cloned DNA sequences and a process for their preparation.
    Type: Grant
    Filed: April 27, 1993
    Date of Patent: December 11, 2012
    Assignees: Institut Pasteur, Centre National de la Recherche Scientifique
    Inventors: Marc Alizon, Francoise Barre Sinoussi, Pierre Sonigo, Pierre Tiollais, Jean-Claude Chermann, Luc Montagnier, Simon Wain-Hobson
  • Patent number: 8236324
    Abstract: An HIV-1 type (or subtype) O retrovirus protein, or a natural or synthetic polypeptide or peptide including at least a part of said protein, which is capable of being recognized by antibodies isolated from a serum resulting from infection by an HIV-1 type O VAU strain or an HIV-1 type (or subtype) O DUR strain.
    Type: Grant
    Filed: November 2, 2006
    Date of Patent: August 7, 2012
    Assignee: Institut Pasteur
    Inventors: Pierre Charneau, François Clavel, Andrew Borman, Caroline Quillent, Denise Guetard, Luc Montagnier, Jacqueline Donjon de Saint-Martin, Jacques Cohen
  • Publication number: 20120024701
    Abstract: A general method for producing EMS positive samples or samples containing nanostructures characteristic of self-replicating molecules like DNA by dilution and agitation. Methods of transduction into DNA information or for inducing EMS in an originating sample and transducing the EMS signal once induced into a naïve receiving sample. Diagnostic methods using this technology.
    Type: Application
    Filed: June 24, 2011
    Publication date: February 2, 2012
    Inventors: LUC MONTAGNIER, Claude Lavallee, Jamal Aissa
  • Publication number: 20110076710
    Abstract: The invention relates to a method for characterising a biologically active biochemical element by analysing low-frequency electromagnetic signals transmitted by a solution prepared from an analysable material sample characterised in that it comprises a pre-filtering stage.
    Type: Application
    Filed: December 14, 2006
    Publication date: March 31, 2011
    Inventor: Luc Montagnier
  • Publication number: 20110027774
    Abstract: Methods for detecting polynucleotides, especially the DNA replicated from samples obtained from subjects infected with pathogenic viruses such as human immunodefiency virus, by detecting electromagnetic signals (“EMS”) emitted by such polynucleotides, and methods for improving the sensitivity of the polymerase chain reaction (“PCR”).
    Type: Application
    Filed: June 10, 2010
    Publication date: February 3, 2011
    Inventor: Luc MONTAGNIER
  • Publication number: 20100323391
    Abstract: This invention concerns a process for preparing reagents intended for a microorganism detection test and notably an infection in humans or animals, wherein the following steps are included: a) Centrifuging a biological or artificial liquid medium containing a selected specific microorganism; b) Filtrating the supernatant obtained in step (a); c) Preparing a series of diluted samples corresponding to increasing dilutions of the filtrate obtained in step (b), down to a filtrate dilution of at least a factor of 10?15; d) Submitting said diluted samples obtained in step (c) to an electrical, magnetic, and/or electromagnetic exciting field; e) Analyzing the electrical signals detected using a solenoid, as well as digitally recording said electrical signal after analog/digital conversion of said signal; f) Selecting diluted samples with which the characteristic electrical signals were obtained in (e), i.e. signals whose amplitude is at least 1.
    Type: Application
    Filed: June 22, 2007
    Publication date: December 23, 2010
    Inventors: Luc Montagnier, Jamal Aissa
  • Patent number: 7777020
    Abstract: This invention encompasses an env nucleic acid product produced by a process comprising providing a sample containing HIV-1 nucleic acid and amplifying the nucleic acid using primer pairs.
    Type: Grant
    Filed: August 15, 2005
    Date of Patent: August 17, 2010
    Assignees: Institut Pasteur, Institut National de la Sante et de la Recherche Medicale
    Inventors: Maurice Moncany, Luc Montagnier
  • Patent number: 7767800
    Abstract: A variant of a LAV virus, designated LAVMAL and capable of causing AIDS. The cDNA and antigens of the LAVMAL virus can be used for the diagnosis of AIDS and pre-AIDS.
    Type: Grant
    Filed: April 17, 2003
    Date of Patent: August 3, 2010
    Assignee: Institut Pasteur
    Inventors: Marc Alizon, Pierre Sonigo, Simon Wain-Hobson, Luc Montagnier
  • Patent number: 7759477
    Abstract: The invention relates to polypeptide fragments of HIV-1, HIV-2, and SIV, antibodies that bind to the polypeptides of the invention, methods of using the antibodies, and kits containing the antibodies. The invention also relates to polynucleotides that encode the polypeptide fragments of the invention.
    Type: Grant
    Filed: June 8, 2004
    Date of Patent: July 20, 2010
    Assignees: Institut Pasteur, Institut National de la Sante et de la Recherche Medicale
    Inventors: Maurice Moncany, Luc Montagnier
  • Patent number: 7626013
    Abstract: The inventors have isolated cloned cDNA encoding the RNA genome of Human Immunodeficiency Virus type 1 (HIV-1). Various clones are described, which encode different regions of the genome, including those regions encoding viral antigens or proteins. Hybridization results indicate the difference between the HIV-1 clones and those of HTLV-I and HTLV-II. The inventors have also produced a restriction map of the entire cloned genomic sequence in order to facilitate further subcloning and using the restriction fragments in other hybridization tests and in methods to express encoded sequences.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: December 1, 2009
    Assignees: Institut-Pasteur, Centre National de la Recherche Scientifique
    Inventors: Marc Alizon, Francoise Barre Sinoussi, Pierre Sonigo, Pierre Tiollais, Jean-Claude Chermann, Luc Montagnier, Simon Wain-Hobson
  • Patent number: 7585619
    Abstract: This invention is in the field of lymphadenopathy virus. This invention relates to a diagnostic means and method of detecting lymphadenopathy associated virus or related viruses or DNA pro-viruses with cloned DNA sequences which are hybridizable to genomic RNA and DNA of lymphadenopathy associated virus. It further relates to the cloned DNA sequences and a process for their preparation.
    Type: Grant
    Filed: February 6, 1995
    Date of Patent: September 8, 2009
    Assignees: Institut Pasteur, Centre National de la Recherche Scientifique
    Inventors: Marc Alizon, Francoise Barre Sinoussi, Pierre Sonigo, Pierre Tiollais, Jean-Claude Chermann, Luc Montagnier, Simon Wain-Hobson
  • Patent number: 7507417
    Abstract: Four glycoproteins of apparent molecular weights 300,000, 140,000, 125,000, and 36,000 (gp300, gp140, gp125, and gp36) are detectable in human immunodeficiency virus type 2 (HIV-2) infected cells. The gp125 and gp36 are the external and transmembrane components, respectively, of the envelope glycoproteins of HIV-2 mature virions. The gp300, which is a dimeric form of gp140, the precursor of HIV-2 envelope glycoprotein, is probably formed by a pH dependent fusion in the endoplasmic reticulum. Such a doublet is also observed in cells infected with simian immunodeficiency virus (SIV), a virus closely related to HIV-2. On the other hand, the envelope glycoprotein precursor of HIV-1 does not form a dimer during its processing. Experiments carried out with various inhibitors of oligosaccharide trimming enzymes suggest that transient dimerization of the glycoprotein precursor is required for its efficient transport to the Golgi apparatus and for its processing.
    Type: Grant
    Filed: September 27, 2005
    Date of Patent: March 24, 2009
    Assignees: Institut Pasteur, Centre National de la Recherche Scientifique
    Inventors: Luc Montagnier, Anne G. Laurent-Crawford, Bernard Krust, Ara G. Hovanessian, Marie-Anne Rey-Cuillé
  • Publication number: 20080261197
    Abstract: An HIV-1 type (or subtype) O retrovirus protein, or a natural or synthetic polypeptide or peptide including at least a part of said protein, which is capable of being recognised by antibodies isolated from a serum resulting from infection by an HIV-1 type O VAU strain or an HIV-1 type (or subtype) O DUR strain.
    Type: Application
    Filed: November 2, 2006
    Publication date: October 23, 2008
    Inventors: Pierre Charneau, Francois Clavel, Andrew Borman, Caroline Quillent, Denise Guetard, Luc Montagnier, Jacqueline Donjon De Saint-Martin, Jacques H.M. Cohen